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Revision as of 02:30, 5 September 2015
P4= Protein Products Pichia Plants
Our Project
Protein Products from Plants and Pichia: Novel Manufacturing of Analgesics and Cannabinoids
Cannabinoids and opiates are widely used classes of pharmaceuticals; unfortunately, these drugs have strong psychoactive effects or can be addictive. Our project consists of two ideas, both revolving around utilizing bioengineered microorganisms to create non-psychoactive cannabinoids and non-addictive analgesics. To achieve this we developed two projects: (1) Manufacturing a protein expression system to produce CBDA synthase in tobacco plants using agrobacterium, (2) Engineering the pGAPα vector system to express the mambalgin in Pichia Pastoris as a continuation of the 2014 GSU iGEM project. Simultaneously, we developed a proof of concept using horseradish peroxidase. By the end of this project we hope to have produced a synthetic biological system to manufacture pharmaceutical alternatives for patients that suffer from diseases such as epilepsy, cancer, or chronic severe pain.
Sponsor
Address
502, DieSachbearbeiter, Schönhauser Allee, 167c10435 Berlin,Germany.
Call Us
+40 (0) 012 345 6789
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