Difference between revisions of "Team:NRP-UEA-Norwich/Practices"

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<h2> Human Practices </h2>
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<p>iGEM teams are unique and leading the field because they "go beyond the lab" to imagine their projects in a social/environmental context, to better understand issues that might influence the design and use of their technologies.</p>
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<p>Teams work with students and advisors from the humanities and social sciences to explore topics concerning ethical, legal, social, economic, safety or security issues related to their work. Consideration of these Human Practices is crucial for building safe and sustainable projects that serve the public interest. </p>
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<p>For more information, please see the <a href="https://2015.igem.org/Practices_Hub">Practices Hub</a>.</p>
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<h4>Note</h4>
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                        <a href="/Team:NRP-UEA-Norwich" class="navbar-brand hidden-lg hidden-md hidden-sm" ><img src="https://static.igem.org/mediawiki/2015/d/d0/TeamNRP-UEA-Norwich-HoC-Logo-White.png" class="img-responsive"></a>
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<p>You must fill out this page in order to be considered for all <a href="https://2015.igem.org/Judging/Awards">awards</a> for Human Practices:</p>
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                    </div>
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<li>Human Practices silver medal criterion</li>
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<li>Human Practices gold medal criterion</li>
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<li>Best Integrated Human Practices award</li>
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<li>Best Education and Public Engagement award</li>
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                                <li><a href="/Team:NRP-UEA-Norwich"  class="logo"><img src="https://static.igem.org/mediawiki/2015/d/d0/TeamNRP-UEA-Norwich-HoC-Logo-White.png" class="img-responsive"></a></li>
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                                    <li  ><a href="/Team:NRP-UEA-Norwich">Home</a></li>
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                                        <li ><a href="/Team:NRP-UEA-Norwich/Project">Background</a></li>
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                                        <li ><a href="/Team:NRP-UEA-Norwich/Modeling/Glyco2D">Glyco2D</a></li>
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                                        <li ><a href="/Team:NRP-UEA-Norwich/Modeling/3DPrinting">How to 3D Print Molecules</a></li>                                   
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                                    <li  ><a href="/Team:NRP-UEA-Norwich/Attributions">Attributions</a></li>
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                                    <li  ><a href="/Team:NRP-UEA-Norwich/Practices">Practices</a></li>
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                                    <li ><a href="/Team:NRP-UEA-Norwich/Collaborations">Collaborations</a></li>                                    
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    <h1 class="title1">Practices Overview</h2>
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    <p class="space20">We built these models to see how changing the parameters such as branching degree and the number of tiers affect the overall structure of the molecule in a more chemically accurate way.</p>
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    <h3 class="title">Glycogen</h2>
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    <p class="space20"> Glycogen is a polysaccharide composed of glucose units linked by alpha 1-4 glycosidic bonds. Each linear chain contains approximately 13 glucose residues and, except of course for the outermost tier of the molecule, a number of alpha 1-6 glycosidic bonds, which allow branching, that are 3–4 residues apart.</p>
  
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        <p class="space20">This simple model - created for our wiki by the SWEET software - shows a small section of a glycogen molecule consisting of 91 glucose units which are contained within 7 branches and 3 tiers. The 1-4 linked sections can be seen to coil into a helical shape, and the 1-6 linkages form helical branches away from the centre of the molecule.</p>
  
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<h5>Some Human Practices topic areas </h5>
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<p class="space20">You can interact with the model using your mouse.</p>
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<li>Philosophy</li>
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<li>Public Engagement / Dialogue</li>
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<li>Education</li>
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<li>Product Design</li>
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<li>Scale-Up and Deployment Issues</li>
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<li>Environmental Impact</li>
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<li>Ethics</li>
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<li>Safety</li>
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<li>Security</li>
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<li>Public Policy</li>
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<li>Law and Regulation</li>
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<li>Risk Assessment</li>
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</ul>
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<h5>What should we write about on this page?</h5>
 
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<p>On this page, you should write about the Human Practices topics you considered in your project, and document any special activities you did (such as visiting experts, talking to lawmakers, or doing public engagement).</p>
 
  
  
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<h5>Inspiration</h5>
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    </div>
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<p>Read what other teams have done:</p>
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    <div class="col-md-5 col-md-offset-1  col-sm-offset-1 space30 text-center">
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<ul>
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                    <div class="success-work science">
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<li><a href="https://2014.igem.org/Team:Dundee/policypractice/experts">2014 Dundee </a></li>
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                        <div class="success-work-desc">
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<li><a href="https://2014.igem.org/Team:UC_Davis/Policy_Practices_Overview">2014 UC Davis </a></li>
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                        <img src="https://static.igem.org/mediawiki/2015/0/0f/TeamNRP-UEA-Norwich-Section-2-Photo.png" class="img-responsive ">
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<li><a href="https://2013.igem.org/Team:Manchester/HumanPractices">2013 Manchester </a></li>
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<li><a href="https://2013.igem.org/Team:Cornell/outreach">2013 Cornell </a></li>
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                          <a title="Lightbox Example" href="#" class="btn outlinebtn  space50">
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                            Read More
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                          </a>
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<h3>Integrated Human Practices</h3>
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    <h3 class="title">Amylose</h2>
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    <p class="space20"> <b>Colon cancer is the second most common cause of cancer death </b> with 30,000 new cases diagnosed every year in England and Wales and a registered cause of death in half that number. </p>
  
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<p>Do you want to be considered for the <a href="https://2015.igem.org/Judging/Awards#SpecialPrizes">Best Integrated Human Practices award</a>? Make it easy for the judges to find any wiki content that is relevant to this prize. Highlight this content with a header or separate section.</p>
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        <p class="space20">Recent studies have suggested that <b>high dietary intake of resistant starch</b> may reduce colon cancer and inflammatory bowel disease. Resistant starches escape digestion in the small intestine and are fermented by microbiota in the colon. A small proportion of these colonic bacteria produce <b>short chain fatty acids including butyrate</b>, which can activate apoptosis in colon cancer cells.</p>
  
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<h3>Education and Public Engagement</h3>
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<p class="space20">Our project is focused on increasing the amount of butyrate in the colon.</p>
  
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<p>Do you want to be considered for the <a href="https://2015.igem.org/Judging/Awards#SpecialPrizes">Best Education and Public Outreach award</a>? Make it easy for the judges to find any wiki content that is relevant to this prize. Highlight this content with a header or separate section.</p>
 
  
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                    <div class="success-work science">
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                        <div class="success-work-desc">
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                        <img src="https://static.igem.org/mediawiki/2015/0/0f/TeamNRP-UEA-Norwich-Section-2-Photo.png" class="img-responsive ">
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                          <a title="Lightbox Example"  href="#" class="btn outlinebtn  space50">
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                            Read More
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<div class="row">
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    <h3 class="title">Amylopectin</h2>
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    <p class="space20"> <b>Colon cancer is the second most common cause of cancer death </b> with 30,000 new cases diagnosed every year in England and Wales and a registered cause of death in half that number. </p>
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        <p class="space20">Recent studies have suggested that <b>high dietary intake of resistant starch</b> may reduce colon cancer and inflammatory bowel disease. Resistant starches escape digestion in the small intestine and are fermented by microbiota in the colon. A small proportion of these colonic bacteria produce <b>short chain fatty acids including butyrate</b>, which can activate apoptosis in colon cancer cells.</p>
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<p class="space20">Our project is focused on increasing the amount of butyrate in the colon.</p>
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                    <div class="success-work science">
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                        <div class="success-work-desc">
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                        <img src="https://static.igem.org/mediawiki/2015/0/0f/TeamNRP-UEA-Norwich-Section-2-Photo.png" class="img-responsive ">
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                          <a title="Lightbox Example"  href="#" class="btn outlinebtn  space50">
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                            Read More
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<div class="space30"></div>
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    <h2 class="title1">References</h2>
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    <p class="space20">http://www.biotopics.co.uk/jsmol/glycogen.html</p>
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<p class="space20">http://watcut.uwaterloo.ca/webnotes/Metabolism/glycogenStructure.html. </p>
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<p class="space20">"Photonic" and "spintronic" computing is the principle of transferring information by light or electron spin.</p>
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            <p class="space20">Currently, copper wires transfer information in a computer; the process is slowed down as the wires heat up. "Photonic" and "spintronic" computing is the principle of transferring information by light or electron spin.</p>
 
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                    <h2 class="gray">MANY THANKS TO OUR SPONSORS</h2>
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Revision as of 13:41, 10 September 2015

House of Carbs

Practices Overview

We built these models to see how changing the parameters such as branching degree and the number of tiers affect the overall structure of the molecule in a more chemically accurate way.

Glycogen

Glycogen is a polysaccharide composed of glucose units linked by alpha 1-4 glycosidic bonds. Each linear chain contains approximately 13 glucose residues and, except of course for the outermost tier of the molecule, a number of alpha 1-6 glycosidic bonds, which allow branching, that are 3–4 residues apart.

This simple model - created for our wiki by the SWEET software - shows a small section of a glycogen molecule consisting of 91 glucose units which are contained within 7 branches and 3 tiers. The 1-4 linked sections can be seen to coil into a helical shape, and the 1-6 linkages form helical branches away from the centre of the molecule.

You can interact with the model using your mouse.

Read More

Amylose

Colon cancer is the second most common cause of cancer death with 30,000 new cases diagnosed every year in England and Wales and a registered cause of death in half that number.

Recent studies have suggested that high dietary intake of resistant starch may reduce colon cancer and inflammatory bowel disease. Resistant starches escape digestion in the small intestine and are fermented by microbiota in the colon. A small proportion of these colonic bacteria produce short chain fatty acids including butyrate, which can activate apoptosis in colon cancer cells.

Our project is focused on increasing the amount of butyrate in the colon.

Read More

Amylopectin

Colon cancer is the second most common cause of cancer death with 30,000 new cases diagnosed every year in England and Wales and a registered cause of death in half that number.

Recent studies have suggested that high dietary intake of resistant starch may reduce colon cancer and inflammatory bowel disease. Resistant starches escape digestion in the small intestine and are fermented by microbiota in the colon. A small proportion of these colonic bacteria produce short chain fatty acids including butyrate, which can activate apoptosis in colon cancer cells.

Our project is focused on increasing the amount of butyrate in the colon.

Read More

References

http://www.biotopics.co.uk/jsmol/glycogen.html

http://watcut.uwaterloo.ca/webnotes/Metabolism/glycogenStructure.html.

"Photonic" and "spintronic" computing is the principle of transferring information by light or electron spin.

Currently, copper wires transfer information in a computer; the process is slowed down as the wires heat up. "Photonic" and "spintronic" computing is the principle of transferring information by light or electron spin.

MANY THANKS TO OUR SPONSORS

Useful Links

Contact Us

  • nrpuea.igem2015@gmail.com

  • Norwich Research Park,
  • Colney,
  • Norwich, NR4 7UH, UK.

We are the NRP-UEA-Norwich 2015 iGEM Team.

Designed and developed by the NRP-UEA-Norwich iGEM Team