Difference between revisions of "Team:WHU-China/DentalCP"
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<span style="margin-bottom:40%">When the concentration of S.mutans in mouth increases, the pH of the micro-environment decreases as well, and reaching to certain level it will activate promoter AsR and induce the reaction downstream in different intensity. The signal intensity will be processed by our criticality detector and an final output signal containing the information whether the antimicrobial peptide gene should or should not be expressed will transfer to the peptide expression circuit to control the expression of antimicrobial peptide. Only when the concentration of S.mutans reaches certain level, can the peptide expression circuit be activated, so that the targeted antimicrobial peptide can inhibit the growth of S.mutans, reducing its population to a lower and healthy level. | <span style="margin-bottom:40%">When the concentration of S.mutans in mouth increases, the pH of the micro-environment decreases as well, and reaching to certain level it will activate promoter AsR and induce the reaction downstream in different intensity. The signal intensity will be processed by our criticality detector and an final output signal containing the information whether the antimicrobial peptide gene should or should not be expressed will transfer to the peptide expression circuit to control the expression of antimicrobial peptide. Only when the concentration of S.mutans reaches certain level, can the peptide expression circuit be activated, so that the targeted antimicrobial peptide can inhibit the growth of S.mutans, reducing its population to a lower and healthy level. | ||
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− | <img src="https://static.igem.org/mediawiki/2015/b/b3/WHU-China_KJT3.png"></img></span> | + | <img src="https://static.igem.org/mediawiki/2015/b/b3/WHU-China_KJT3.png" width="600"></img></span> |
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Revision as of 16:53, 11 September 2015