Difference between revisions of "Team:NTU-LIHPAO-Taiwan/Entrepreneurship"

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<div class="Text1">Overview</div>
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<div class="Text1">Entrepreneurship</div>
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<div class="Text2" id="First1">Pigout Versus Stay in Shape</div>
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<div class="Text2" id="First1">Motivation</div>
 
<div class="Text3">
 
<div class="Text3">
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This year, iGEM team of NTU-LIHPAO-Taiwan take note of the problem that the obesity condition in Taiwan has deteriorated. Moreover, the market is flooded with those unverified slimming drugs that harm the public health simultaneously. Therefore, we hope to initiate our project from the key peptide “Peptide YY (PYY)” which can control appetite, and take advantage of the probiotic characteristic of <i>Lactobacillus casei</i>, with cell penetrating peptides which contain large developmental potential in oral peptide drugs. We hope that we can make <i>Lactobacillus casei</i> secret CPP-PYY complex which can be another newly created oral peptide drugs.
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According to the World Health Organization research, unhealthy diet, physical inactivity and obesity, accounting for 30 percent of cancer death! Obese people suffer from the risk of colorectal cancer, also 1-2 times higher than normal people.
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</div>
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<div class="Text3">
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Also Taiwan ministry of health and welfare reveals that the prevalence of obesity in Taiwanese people is the highest among Asian. About 1/2 adult male, 1/3 female, 1/4 of children are overweight or obesity. Furthermore, obesity related chronic disease also cost 500 billion NTD expense each year. Among all kinds of factor casing obesity, the biggest culprit is overeating and lack of exercising. Therefore, the first step in a healthy weight loss diet must first learn how to eat smart. To tackle this situation, we design appetite control tonic using the new development technique- oral peptide drug for absorbing directly in the gastrointestinal and peptide YY to reduce the appetite, but does not affect insulin, glucagon secretion and heath.
 
</div>
 
</div>
  
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<div class="Text2" id="First1">Product</div>
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<div class="Text3">
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We take note of the problem that the obesity condition in Taiwan has deteriorated. Therefore, we hope to initiate our project from the key peptide “Peptide YY (PYY)” which can control appetite, and take advantage of the probiotic characteristic of <i>Lactobacillus casei</i>, with cell penetrating peptides (CPP) which is prospective in oral peptide drugs. We hope that we can make Lactobacillus casei secret CPP-PYY complex becoming another newly created oral peptide drugs that help us to lose weight in a healthier way.
 +
</div>
 +
<div class="Text3">
 +
Our product- Healthin comprises of 2 factor, Health and Thin. We hope that once the customer take our oral peptide drug, they will regain their health can become thin rather than sacrifice their good health and ruin their body.
 +
</div>
 +
<div class="Text3">
 +
Just as the famous probiotic beverage Yakult, we design our product in the same way. In the product, it looks like and function like the Yakult. However, once our lactobacillus reaches intestine and senses the bile salt, it will start producing CPP-PYY complex. Besides, our lactobacillus will also have the probiotic effect just as the Yakult’s does. CPP-PYY complex will then absorb by the epidermal cell of the villi and approach blood vessel. PYY will circulate with the blood and finally bind to the Y2 receptor in the hypothalamus. Once binding, you will feel a sense of fulfillment and lessen your food intake.
 +
</div>
 +
<div class="Text3">
 +
We hope that our product can reduce appetite and finally achieve our goal- a healthier life which make the customer health and thin.
 +
</div>
  
 +
<div class="Text1">Market Analysis</div>
  
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<div class="Text2" id="First1">Globesity</div>
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<div class="Text3">
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Globesity, a new word from global and obesity, was born in these years, which represents the problem of worldwide obesity problem has been more and more serious.
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</div>
  
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<div class="Text2" id="First1">What is OBESITY and OVERWEIGHT?</div>
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<div class="Text3">
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Overweight and obesity are defined as abnormal or excessive fat accumulation that may impair health. The WHO definition is:
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</div>
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<div class="Text3">
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<ol class="part1">
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        <li>A BMI greater than or equal to 30 is obesity</li>
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        <li>A BMI greater than or equal to 25 is overweight</li>
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</ol>
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</div>
  
  

Revision as of 17:12, 13 September 2015

NTU-LIHPAO-Taiwan

Entrepreneurship
Motivation
According to the World Health Organization research, unhealthy diet, physical inactivity and obesity, accounting for 30 percent of cancer death! Obese people suffer from the risk of colorectal cancer, also 1-2 times higher than normal people.
Also Taiwan ministry of health and welfare reveals that the prevalence of obesity in Taiwanese people is the highest among Asian. About 1/2 adult male, 1/3 female, 1/4 of children are overweight or obesity. Furthermore, obesity related chronic disease also cost 500 billion NTD expense each year. Among all kinds of factor casing obesity, the biggest culprit is overeating and lack of exercising. Therefore, the first step in a healthy weight loss diet must first learn how to eat smart. To tackle this situation, we design appetite control tonic using the new development technique- oral peptide drug for absorbing directly in the gastrointestinal and peptide YY to reduce the appetite, but does not affect insulin, glucagon secretion and heath.
Product
We take note of the problem that the obesity condition in Taiwan has deteriorated. Therefore, we hope to initiate our project from the key peptide “Peptide YY (PYY)” which can control appetite, and take advantage of the probiotic characteristic of Lactobacillus casei, with cell penetrating peptides (CPP) which is prospective in oral peptide drugs. We hope that we can make Lactobacillus casei secret CPP-PYY complex becoming another newly created oral peptide drugs that help us to lose weight in a healthier way.
Our product- Healthin comprises of 2 factor, Health and Thin. We hope that once the customer take our oral peptide drug, they will regain their health can become thin rather than sacrifice their good health and ruin their body.
Just as the famous probiotic beverage Yakult, we design our product in the same way. In the product, it looks like and function like the Yakult. However, once our lactobacillus reaches intestine and senses the bile salt, it will start producing CPP-PYY complex. Besides, our lactobacillus will also have the probiotic effect just as the Yakult’s does. CPP-PYY complex will then absorb by the epidermal cell of the villi and approach blood vessel. PYY will circulate with the blood and finally bind to the Y2 receptor in the hypothalamus. Once binding, you will feel a sense of fulfillment and lessen your food intake.
We hope that our product can reduce appetite and finally achieve our goal- a healthier life which make the customer health and thin.
Market Analysis
Globesity
Globesity, a new word from global and obesity, was born in these years, which represents the problem of worldwide obesity problem has been more and more serious.
What is OBESITY and OVERWEIGHT?
Overweight and obesity are defined as abnormal or excessive fat accumulation that may impair health. The WHO definition is:
  1. A BMI greater than or equal to 30 is obesity
  2. A BMI greater than or equal to 25 is overweight
Maintained by the iGEM team NTU-LIHPAO-Taiwan    ©2015 NTU-LIHPAO-Taiwan