Difference between revisions of "Team:TU Dresden/Modeling"

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<ul>
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<a href="https://2015.igem.org/Team:TU_Dresden"><li>HOME</li></a>
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<a href="#"><li>TEAM
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            <ul>
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<a href="https://2015.igem.org/Team:TU_Dresden/About_us"><li>About us</li></a> 
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<a href="https://2015.igem.org/Team:TU_Dresden/Acknowledgements"><li>Acknowledgements</li></a> 
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<a href="https://2015.igem.org/Team:TU_Dresden/Contact us"><li>Contact us</li></a>
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</ul>
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</li></a>
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<a href="#"><li>PROJECT
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            <ul>
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<a href="https://2015.igem.org/Team:TU_Dresden/Description"><li>Description</li></a>
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<a href="https://2015.igem.org/Team:TU_Dresden/Methods"><li>Methods</li></a> 
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<a href="https://2015.igem.org/Team:TU_Dresden/Results"><li>Results</li></a> 
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<a href="https://2015.igem.org/Team:TU_Dresden/Design"><li>Design</li></a>
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</ul>
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</li></a>
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<a href="#"><li>PARTS
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            <ul>
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<a href="https://2015.igem.org/Team:TU_Dresden
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/Parts"><li>Team Parts</li></a>
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<a href="https://2015.igem.org/Team:TU_Dresden/Basic_Part"><li>Basic Parts</li></a> 
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<a href="https://2015.igem.org/Team:TU_Dresden/Composite_Part"><li>Composite Parts</li></a>
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<a href="https://2015.igem.org/Team:TU_Dresden/Part_Collection"><li>Part Collection</li></a> 
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</ul>
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</li></a>
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<a href="https://2015.igem.org/Team:TU_Dresden/Notebook"><li>NOTEBOOK</li></a>
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<a href="https://2015.igem.org/Team:TU_Dresden/Attributions"><li>ATTRIBUTIONS</li></a>
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<a href="https://2015.igem.org/Team:TU_Dresden/Collaborations"><li>COLLABORATIONS</li></a>
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<a href="https://2015.igem.org/Team:TU_Dresden/Practices"><li>HUMAN PRACTICES</li></a>
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<a href="https://2015.igem.org/Team:TU_Dresden/Safety"><li>SAFETY</li></a>
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<a href="https://2015.igem.org/Team:TU_Dresden/Modeling"><li>MODELING</li></a>
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<a href="https://2015.igem.org/Team:TU_Dresden/Measurement"><li>MEASUREMENT</li></a>
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<a href="https://2015.igem.org/Team:TU_Dresden/Software"><li>SOFTWARE</li></a>
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<a href="https://2015.igem.org/Team:TU_Dresden/Entrepreneurship"><li>ENTREPRENEURSHIP</li></a>
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</ul>
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</div>
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</html>
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<h2> Modeling</h2>
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<div class="highlightBox">
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<h4>Note</h4>
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<p>In order to be considered for the <a href="https://2015.igem.org/Judging/Awards#SpecialPrizes">Best Model award</a>, you must fill out this page.</p>
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</div>
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<body>
  
<p>Mathematical models and computer simulations provide a great way to describe the function and operation of BioBrick Parts and Devices. Synthetic Biology is an engineering discipline, and part of engineering is simulation and modeling to determine the behavior of your design before you build it. Designing and simulating can be iterated many times in a computer before moving to the lab. This award is for teams who build a model of their system and use it to inform system design or simulate expected behavior in conjunction with experiments in the wetlab.</p>
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<div id="TueContent">
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<p></p>
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<h1>Models</h1>
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<p></p>
  
<p>
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<h4>Structure analysis of our targets and their interactions</h4>
Here are a few examples from previous teams:
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  <p style="line-height:1.8">In order to better understand the interaction between the affibody and HER2, we created a subproject that aimed to analyse it. As results the following video was obtained. In this simulation, the interaction can be observed in a detailed manner. To read more about the video, please refer to <a style="text-decoration:none;" href="https://2015.igem.org/Team:TU_Dresden/Project/Results#structure"><font color="#045FB4">Results</font></a>.</p>
</p>
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<ul>
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<li><a href="https://2014.igem.org/Team:ETH_Zurich/modeling/overview">ETH Zurich 2014</a></li>
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<li><a href="https://2014.igem.org/Team:Waterloo/Math_Book">Waterloo 2014</a></li>
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</ul>
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    <div align="center"><video poster="https://static.igem.org/mediawiki/2015/2/2a/TU_Dresden_start_video_interactions.png" controls>
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    <source src="https://static.igem.org/mediawiki/2015/8/83/TU_Dresden_Structure_interaction_mp4.mp4" type='video/mp4'/>
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    <source src="https://static.igem.org/mediawiki/2015/5/5b/TU_Dresden_Structure_interaction_ogg.ogg" type='video/ogg; codecs="theora, vorbis"'/>
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    <source src="https://2015.igem.org/File:TU_Dresden_structure_interaction_webm.webm" type='video/webm; codecs="vp8, vorbis"'/>
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    <a href="https://www.youtube.com/watch?v=hywgKEGoZJ0&feature=youtu.be"><img border="0" src="https://static.igem.org/mediawiki/2015/2/2a/TU_Dresden_start_video_interactions.png" alt="Click to view on Youtube" width="500" height="281.25"></a>
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    <p style="font-style:italic;color:red;border-style:solid;border-width:2px;border-color:red">Your browser either does not support HTML5 or cannot handle MediaWiki open video formats. Please consider upgrading your browser, installing the appropriate plugin or switching to another browser.</p>
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    </video>
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    </div>
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<p></p>
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<h4>Set up of flow system</h4>
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<p style="line-height:1.8">The second model we needed to design was the set up of the flow system. It was necessary to create a working setup in order to make the whole project work. More information can be found in <a style="text-decoration:none;" href="https://2015.igem.org/Team:TU_Dresden/Project/Description#setup"><font color="#045FB4">Description</font></a>.</p>
  
</div>
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<figure align="center">
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<a href="https://static.igem.org/mediawiki/2015/b/b2/TU_Dresden_PACE_setup.jpg" title="View">
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  <IMG SRC="https://static.igem.org/mediawiki/2015/b/b2/TU_Dresden_PACE_setup.jpg" style="width: 80%;"/></a>
  
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Revision as of 21:43, 16 September 2015


Models

Structure analysis of our targets and their interactions

In order to better understand the interaction between the affibody and HER2, we created a subproject that aimed to analyse it. As results the following video was obtained. In this simulation, the interaction can be observed in a detailed manner. To read more about the video, please refer to Results.

Set up of flow system

The second model we needed to design was the set up of the flow system. It was necessary to create a working setup in order to make the whole project work. More information can be found in Description.