Difference between revisions of "Team:Warwick/Modeling"
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<p><a href="BindingAffinity"><h5>Binding Affinity Modelling</h5><p style="float: left;"><img src="https://static.igem.org/mediawiki/2015/6/66/Warwickmodeling5.png" align="right" height="100px" width="100px" border="1px"></p></p> </a> | <p><a href="BindingAffinity"><h5>Binding Affinity Modelling</h5><p style="float: left;"><img src="https://static.igem.org/mediawiki/2015/6/66/Warwickmodeling5.png" align="right" height="100px" width="100px" border="1px"></p></p> </a> | ||
| − | A big problem biologists encounter is the uncertainty of bonding especially in our design where zinc fingers bind to cells. Therefore it is important to come up with a model which can calculate the number of cell and zinc finger binding sites required for a given output. This page discusses this and shows a program designed to dictate concentrations for the biologists to use.<br> | + | A big problem biologists encounter is the uncertainty of bonding especially in our design where zinc fingers bind to cells. Therefore it is important to come up with a model which can calculate the number of cell and zinc finger binding sites required for a given output. This page discusses this and shows a program designed to dictate concentrations for the biologists to use.<br><br> |
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Once we had a method of calculating the concentration of cells needed we had to model the number of cells required to make a certain shape. We also needed to invent a novel approach to creating 2D shapes using cells, this page discusses bonding them to a longer string of DNA to form a pattern. | Once we had a method of calculating the concentration of cells needed we had to model the number of cells required to make a certain shape. We also needed to invent a novel approach to creating 2D shapes using cells, this page discusses bonding them to a longer string of DNA to form a pattern. | ||
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<p><a href="Modelling2"><h5>DNA Origami Glue Modelling</h5><p style="float: left;"><img src="https://static.igem.org/mediawiki/2015/7/74/WarwickE.coli_Bonded_to_Origami.png" align="right" height="100px" width="100px" border="1px"></p></p> </a> | <p><a href="Modelling2"><h5>DNA Origami Glue Modelling</h5><p style="float: left;"><img src="https://static.igem.org/mediawiki/2015/7/74/WarwickE.coli_Bonded_to_Origami.png" align="right" height="100px" width="100px" border="1px"></p></p> </a> | ||
| − | + | After the inherent problems and issues found from using the first model of 2D shapes we came up with a second, which discusses the use of DNA as an oligonucleotide adhesive to create 2D and 3D structures and shapes.<br> | |
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Revision as of 09:26, 17 September 2015
