Difference between revisions of "Team:BostonU/Design"
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| + | Our team was able to demonstrate a split TP901-1 protein prototype. Using the model developed in MATLAB, we were able to identify several different places to rationally split a protein. Both inert protein fragments were fused to dimerization domains, that naturally bind in the presence of an inducer. The protein showed low basal activity, and regained activity in the presence of the inducer. | ||
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Revision as of 16:32, 18 September 2015
Overview
Our team was able to demonstrate a split TP901-1 protein prototype. Using the model developed in MATLAB, we were able to identify several different places to rationally split a protein. Both inert protein fragments were fused to dimerization domains, that naturally bind in the presence of an inducer. The protein showed low basal activity, and regained activity in the presence of the inducer.