Difference between revisions of "Template:Heidelberg/project/standardization/HRP"
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HRP-mimicking DNAzyme folds into a G-quadruplex and binds hemin into it. Upon binding of the hemin to the G-quadruplex the DNAzyme catalyzes the reduction of H<sub>2</sub>O<sub>2</sub> to H<sub>2</sub>O and a reactive oxygen species and thus result to the activation of a classical HRP substrate like luminol. | HRP-mimicking DNAzyme folds into a G-quadruplex and binds hemin into it. Upon binding of the hemin to the G-quadruplex the DNAzyme catalyzes the reduction of H<sub>2</sub>O<sub>2</sub> to H<sub>2</sub>O and a reactive oxygen species and thus result to the activation of a classical HRP substrate like luminol. | ||
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Revision as of 19:58, 18 September 2015
HRP-mimicking DNAzyme
HRP-mimicking DNAzyme folds into a G-quadruplex and binds hemin into it. Upon binding of the hemin to the G-quadruplex the DNAzyme catalyzes the reduction of H2O2 to H2O and a reactive oxygen species and thus result to the activation of a classical HRP substrate like luminol.
HRP-micking DNAzyme
HRP-mimicking DNAzyme folds into a G-quadruplex and binds hemin into it. Upon binding of the hemin to the G-quadruplex the DNAzyme catalyzes the reduction of H2O2 to H2O and a reactive oxygen species and thus result to the activation of a classical HRP substrate like luminol.