Difference between revisions of "Team:USTC-Software"

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     GENE CIRCUIT<br>See the detailed structure of a designed gene circuit
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     Gene Network<br>See the detailed structure of a designed gene circuit
 
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     A single click on “?” button will bring you to another tab<br>
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     A simple click on “Gene network” button will lead you to another tab where the detailed structure of your designed gene circuit is shown. When a gene circuit consists of many Boolean gates, it is crucial to understand the internal substances and mechanisms. In this tab, you can see how substances react with each other clearly, such as inhibition and activation in or between Boolean gates.
    where the detailed structure of your designed gene circuit<br>
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    is shown. If you want to see the abstract structure, just<br>
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    click “?” button and you will see configuration of every<br>
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    Boolean gate hidden behind gate symbols.
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     Given a designed gene circuit, such as a simple serial circuit<br>
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     Given a designed gene circuit, such as a simple serial circuit composed of an AND gate and an OR gate, you can use our default parameters and change initial concentration of reactants to get simulation results.
    composed of an AND gate and a OR gate, you only need to input<br>
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If you want to get different results, you just need to change system parameters such as the rate of reactions, namely, to fill constants into the dialog boxes on our canvas.  
    parameters to confirm the initial concentration of reactants<br>
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What’s more, simulation time slot is necessary as well to give concentration-time figures of the inputs and outputs of a given gene circuit. You are free to see the concentration-time evolution of every substance in designed gene circuits individually.
    and the rate of reactions, namely, to fill constant into the<br>
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    dialog boxes corresponding to designed gene circuits on our<br>
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    canvas. Simulation time slot is needed as well to give<br>
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    concentration-time figures of the inputs and outputs of a<br>
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    given gene circuit.
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     While offering various functions, BioBLESS also serves as<br>
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     Given a designed gene circuit, such as a simple serial circuit composed of an AND gate and an OR gate, you can use our default parameters and change initial concentration of reactants to get simulation results.  
    analysis tool for designed gene circuit. When you have<br>
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If you want to get different results, you just need to change system parameters such as the rate of reactions, namely, to fill constants into the dialog boxes on our canvas.
    designed a gene circuit, you can click the “analysis”<br>
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What’s more, simulation time slot is necessary as well to give concentration-time figures of the inputs and outputs of a given gene circuit. You are free to see the concentration-time evolution of every substance in designed gene circuits individually.
    button to reset robustness analysis parameters. Meanwhile,<br>
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    BioBLESS will set simulation slots and carry the simulation<br>
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    task automatically. According to the<br>
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    perturbation-to-background ratio you input, such as 20%<br>
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    or 30%, the concentration-time curves of inputs and<br>
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    outputs will be shown together to give<br>
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    a visualized intuition on the robustness<br>
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    of a designed gene circuit.
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Revision as of 00:00, 19 September 2015

GoTo

Bio
B
L
E
S
S

Logic
From a truth table to abstract logic circuits

In BioBLESS, a truth table dialog box will be displayed for users to input Boolean numbers 0/1. All you need to do is to click Boolean buttons and then “Create”. The corresponding designed logic circuits with different predicted performances will be automatically generated and displayed in order. You can immediately and clearly see the configuration of a designed logic circuit, which in most cases is supposed to be a complicated multi-input circuit. Besides the function above, gates list will provide many Boolean gates, and users can drag them freely to our canvas to design logic circuits.

Gene Network
See the detailed structure of a designed gene circuit

A simple click on “Gene network” button will lead you to another tab where the detailed structure of your designed gene circuit is shown. When a gene circuit consists of many Boolean gates, it is crucial to understand the internal substances and mechanisms. In this tab, you can see how substances react with each other clearly, such as inhibition and activation in or between Boolean gates.

SIMULATION
Get concentration-time simulation results

Given a designed gene circuit, such as a simple serial circuit composed of an AND gate and an OR gate, you can use our default parameters and change initial concentration of reactants to get simulation results. If you want to get different results, you just need to change system parameters such as the rate of reactions, namely, to fill constants into the dialog boxes on our canvas. What’s more, simulation time slot is necessary as well to give concentration-time figures of the inputs and outputs of a given gene circuit. You are free to see the concentration-time evolution of every substance in designed gene circuits individually.

ANALYSIS
Get robustness and sensitivity analysis

Given a designed gene circuit, such as a simple serial circuit composed of an AND gate and an OR gate, you can use our default parameters and change initial concentration of reactants to get simulation results. If you want to get different results, you just need to change system parameters such as the rate of reactions, namely, to fill constants into the dialog boxes on our canvas. What’s more, simulation time slot is necessary as well to give concentration-time figures of the inputs and outputs of a given gene circuit. You are free to see the concentration-time evolution of every substance in designed gene circuits individually.

DNA
Get the DNA sequence!

Users have the freedom to drag specific BioBricks on our canvas and
combine them into a functional gene circuit. Then the DNA sequence
and other information of the designed circuit are available for users
to check and download. Wet lab protocols are partly incorporated into
our DNA sequences which may make the design better and applicable in
laboratories.

University of Science and Technology of China
No.96, Jinzhai Road, Hefei, Anhui, P.R.China
USTC-Software 2015

University of Science and Technology of China

We are here for you

Sponsered by

University of Science and Technology of China
No.96, Jinzhai Road, Hefei, Anhui, P.R.China
USTC-Software 2015

University of Science and Technology of China

We are here for you

Sponsered by