Difference between revisions of "Team:Leicester/Description"

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<h2> Project Description </h2>
 
<h2> Project Description </h2>
  
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<p>Tell us about your project, describe what moves you and why this is something important for your team.</p>
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<p> We are The University of Leicester iGEM team. The first part of our project is generating genetically modified bacteria that can colonise the gut without disrupting the bacteria already there. We are proposing to do this by binding the bacteria to surface proteins that are on the bacteria that is already in the gut. </p>
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<p> The second part of our project is to use this bacteria as a delivery system which excretes an enzyme called NMNAT. This enzyme is part of the NAD+ pathway and increasing NMNAT concentrations in the human body (via the bacteria) should increase NAD+ production. More NAD+ in the human body, according to some literature, aid in the treatment of neurodegenerative disorders like Parkinson's disease and Alzheimer's disease as well as helping to combat muscle fatigue. </p>
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<h5>What should this page contain?</h5>
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<li> A clear and concise description of your project.</li>
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<li>A detailed explanation of why your team chose to work on this particular project.</li>
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<li>References and sources to document your research.</li>
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<li>Use illustrations and other visual resources to explain your project.</li>
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<h4>Advice on writing your Project Description</h4>
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We encourage you to put up a lot of information and content on your wiki, but we also encourage you to include summaries as much as possible. If you think of the sections in your project description as the sections in a publication, you should try to be consist, accurate and unambiguous in your achievements.  
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Judges like to read your wiki and know exactly what you have achieved. This is how you should think about these sections; from the point of view of the judge evaluating you at the end of the year.
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<h4>References</h4>
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<p>iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you though about your project and what works inspired you.</p>
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<h4>Inspiration</h4>
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<p>See how other teams have described and presented their projects: </p>
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<li><a href="https://2014.igem.org/Team:Imperial/Project"> Imperial</a></li>
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<li><a href="https://2014.igem.org/Team:UC_Davis/Project_Overview"> UC Davis</a></li>
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<li><a href="https://2014.igem.org/Team:SYSU-Software/Overview">SYSU Software</a></li>
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Revision as of 22:47, 14 July 2015

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Project Description

We are The University of Leicester iGEM team. The first part of our project is generating genetically modified bacteria that can colonise the gut without disrupting the bacteria already there. We are proposing to do this by binding the bacteria to surface proteins that are on the bacteria that is already in the gut.

The second part of our project is to use this bacteria as a delivery system which excretes an enzyme called NMNAT. This enzyme is part of the NAD+ pathway and increasing NMNAT concentrations in the human body (via the bacteria) should increase NAD+ production. More NAD+ in the human body, according to some literature, aid in the treatment of neurodegenerative disorders like Parkinson's disease and Alzheimer's disease as well as helping to combat muscle fatigue.