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Our team's aim is to create a tool box allowing the selective allocation of specific cell types to an engineered DNA scaffold, using zinc finger binding proteins on an E. coli model. Our research would allow for the self assembly of complex multi-type cell structures. The project will advance in progressive bands of complexity: designing and cloning the zinc finger coated E. coli cells, constructing DNA structure to allow for the cells to bind, further development of the zinc finger binding proteins allowing for multiple cell types to coexist on the DNA structure, and finally designing complex 3-D structures that the cells will be able to self assemble into. This has possible applications throughout medicine. Our research would contribute potentially to 3-D printing organic tissues, allowing for customised living tissues to be engineered.
 
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Revision as of 15:04, 24 July 2015

Warwick iGEM 2015

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Brixcells

Our team's aim is to create a tool box allowing the selective allocation of specific cell types to an engineered DNA scaffold, using zinc finger binding proteins on an E. coli model. Our research would allow for the self assembly of complex multi-type cell structures. The project will advance in progressive bands of complexity: designing and cloning the zinc finger coated E. coli cells, constructing DNA structure to allow for the cells to bind, further development of the zinc finger binding proteins allowing for multiple cell types to coexist on the DNA structure, and finally designing complex 3-D structures that the cells will be able to self assemble into. This has possible applications throughout medicine. Our research would contribute potentially to 3-D printing organic tissues, allowing for customised living tissues to be engineered.

E.Coli
DNA Origami
Our Idea

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