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<h5 class="sidebartitle">Tetrahedron Construction</h5>
 
<h5 class="sidebartitle">Tetrahedron Construction</h5>
 
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<img src="images/settings.png" class="pics" alt=""> ADD DESCRIPTION...............................................................
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<img src="https://static.igem.org/mediawiki/2015/3/37/WarwickSelf_assembly.jpg" class="pics" alt=""> The aim of this model is to design a 3D, self-assembling structure which forms a shape which allows E-coli cells to be bonded to the outside. One of the shapes we decided to use is a geodesic sphere made up of multiple tetrahedron ‘bricks’. Tetrahedrons are the strongest 3D structure and would allow any sized scaffold to be made. A sphere is the best 3D structure as it has the largest surface area to volume ratio which will allow the largest number of E.coli cells to bond to it.
 
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Revision as of 15:01, 5 August 2015

Warwick iGEM 2015

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Binding E.coli to a DNA Structure

Concept and Use

ADD DESCRIPTION...............................................................

Cube Construction

This shows how the DNA strands come together. Three double stranded strings of DNA are denatured and then when slowly cooled will come together to form the Y shape. However after the denaturing each strand of DNA has an equal chance of bonding to the original piece of DNA as it does to the correct origami side. Therefore the more complex the structure the less likely it is that that structure will fully form.

Tetrahedron Construction

The aim of this model is to design a 3D, self-assembling structure which forms a shape which allows E-coli cells to be bonded to the outside. One of the shapes we decided to use is a geodesic sphere made up of multiple tetrahedron ‘bricks’. Tetrahedrons are the strongest 3D structure and would allow any sized scaffold to be made. A sphere is the best 3D structure as it has the largest surface area to volume ratio which will allow the largest number of E.coli cells to bond to it.


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