Difference between revisions of "Team:RHIT"
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| − | With manufacturing applications in mind, our team aims to affect production of yeast secondary metabolites through the regulation of aerobic respiration. Our project accomplishes this task by disabling translation in the mitochondria, which necessitates fermentation. Specifically, we aim to control the expression of the mitochondrial ribosomal protein S12 gene <span style="font-style:italic">(MRPS12) </span>. This protein is essential for mitochondrial translation. To control this gene, the copper sensitive promoter, CTR1, will be | + | With manufacturing applications in mind, our team aims to affect production of yeast secondary metabolites through the regulation of aerobic respiration. Our project accomplishes this task by disabling translation in the mitochondria, which necessitates fermentation. Specifically, we aim to control the expression of the mitochondrial ribosomal protein S12 gene <span style="font-style:italic">(MRPS12) </span>. This protein is essential for mitochondrial translation. To control this gene, the copper sensitive promoter, CTR1, will be utilized. This system should allow us to turn aerobic respiration on and off by manipulating copper levels in the medium. |
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Revision as of 15:55, 5 August 2015
Welcome to Rose-Hulman's MitochONdriOFF project!
We're excited you're here! feel free to look around, but this website is still under construction, so there are a lot of glitches. The construction of this website will end on September 18th, 2015. Thanks!
Click here to edit this page!Project Description
Saccharomyces cerevisiae is widely utilized in various industries in the production of alcoholic beverages, biofuel, and other organic compounds. Many of these products are secondary metabolites. Novel ways of controlling fermentation could lead to more efficient and effective methods for the industrial production of these products.
With manufacturing applications in mind, our team aims to affect production of yeast secondary metabolites through the regulation of aerobic respiration. Our project accomplishes this task by disabling translation in the mitochondria, which necessitates fermentation. Specifically, we aim to control the expression of the mitochondrial ribosomal protein S12 gene (MRPS12) . This protein is essential for mitochondrial translation. To control this gene, the copper sensitive promoter, CTR1, will be utilized. This system should allow us to turn aerobic respiration on and off by manipulating copper levels in the medium.