Difference between revisions of "Team:TCU Taiwan/Project/Overview"
Line 72: | Line 72: | ||
<td> | <td> | ||
<p align="justify" ><span style="font-family:Levenim MT;line-height: 150%;"><font size="4"> | <p align="justify" ><span style="font-family:Levenim MT;line-height: 150%;"><font size="4"> | ||
− | <a href="https://2015.igem.org/Team:TCU_Taiwan/Project/Our_Design"> Antimicrobial peptide</a> | + | <p><a href="https://2015.igem.org/Team:TCU_Taiwan/Project/Our_Design"> Antimicrobial peptide</a> |
− | < | + | </p> |
− | • Epinecidin-1: | + | |
− | + | <p> • Epinecidin-1:</p> | |
− | 1. from the skin mucus of Epinephelus coioides a kind of fish. | + | |
− | + | <p> 1. from the skin mucus of Epinephelus coioides a kind of fish. | |
+ | </p> | ||
+ | <p> | ||
2. has function of killing bacteria. | 2. has function of killing bacteria. | ||
− | + | </p> | |
+ | <p> | ||
3. In addition, it has the ability to help wounds healing and has been proven by animal studies. | 3. In addition, it has the ability to help wounds healing and has been proven by animal studies. | ||
− | + | </p> | |
<br> | <br> | ||
<br> | <br> | ||
− | • Signiferin: | + | <p> • Signiferin: |
− | + | </p> | |
+ | <p> | ||
1. from the skin mucus of Crinia signifera a kind of tree frog. | 1. from the skin mucus of Crinia signifera a kind of tree frog. | ||
− | + | </p> | |
+ | <p> | ||
2. have function of killing bacteria. | 2. have function of killing bacteria. | ||
− | + | </p> | |
+ | <p> | ||
3. have great ability in disinfect Methicillin-Resistant Staphylococcus aureus (MRSA). | 3. have great ability in disinfect Methicillin-Resistant Staphylococcus aureus (MRSA). | ||
− | + | </p> | |
+ | <p> | ||
4. had already been kindly proved by the 2013 TU-Delft iGEM team. | 4. had already been kindly proved by the 2013 TU-Delft iGEM team. | ||
+ | </p> | ||
<br> | <br> | ||
<br> | <br> | ||
− | < | + | <p> |
<a href="https://2015.igem.org/Team:TCU_Taiwan/Project/Experimental"> • Signal peptide: </a> | <a href="https://2015.igem.org/Team:TCU_Taiwan/Project/Experimental"> • Signal peptide: </a> | ||
− | < | + | </p> |
1. helps AMPs to secret out of E. coli. | 1. helps AMPs to secret out of E. coli. | ||
− | < | + | <p> |
2. from Streptomyces lividans to trasport chitinase C to secretion system, which has been proven to work in E.coli by reference. | 2. from Streptomyces lividans to trasport chitinase C to secretion system, which has been proven to work in E.coli by reference. | ||
+ | </p> | ||
<br> | <br> | ||
<br> | <br> | ||
− | + | ||
− | < | + | <p> |
<a href="https://2015.igem.org/Team:TCU_Taiwan/Project/Reference"> • Wound dressing:</a> | <a href="https://2015.igem.org/Team:TCU_Taiwan/Project/Reference"> • Wound dressing:</a> | ||
− | < | + | </p> |
+ | <p> | ||
Based on AMPs to develop into a potential material of wound dressing. | Based on AMPs to develop into a potential material of wound dressing. | ||
− | < | + | </p> |
Revision as of 05:47, 6 August 2015
AMP. coli |
AMPs have an extensive ability in disinfect. Unlike antibiotics, AMPs can puncture the cell membrane to kill the bacteria therefore by passing bacterial antibiotic drug resistance mechanisms. Two kinds of AMPs were selected as our reagents: Epinecidin-1 and Signiferin.
|
• Epinecidin-1: 1. from the skin mucus of Epinephelus coioides a kind of fish.
2. has function of killing bacteria.
3. In addition, it has the ability to help wounds healing and has been proven by animal studies.
• Signiferin:
1. from the skin mucus of Crinia signifera a kind of tree frog.
2. have function of killing bacteria.
3. have great ability in disinfect Methicillin-Resistant Staphylococcus aureus (MRSA).
4. had already been kindly proved by the 2013 TU-Delft iGEM team.
2. from Streptomyces lividans to trasport chitinase C to secretion system, which has been proven to work in E.coli by reference.
Based on AMPs to develop into a potential material of wound dressing.
|
![]() ![]() ![]() ![]() ![]() |
|
Contact us tcutaiwan@gmail.com No.701, Sec. 3, Zhongyang Rd. Hualien 97004, Taiwan |