Difference between revisions of "Team:TCU Taiwan/Project/Overview"
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<p><a href="https://2015.igem.org/Team:TCU_Taiwan/Project/Our_Design"> Antimicrobial peptide</a> | <p><a href="https://2015.igem.org/Team:TCU_Taiwan/Project/Our_Design"> Antimicrobial peptide</a> | ||
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<p> • Epinecidin-1:</p> | <p> • Epinecidin-1:</p> | ||
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<a href="https://2015.igem.org/Team:TCU_Taiwan/Project/Experimental"> • Signal peptide: </a> | <a href="https://2015.igem.org/Team:TCU_Taiwan/Project/Experimental"> • Signal peptide: </a> | ||
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1. helps AMPs to secret out of E. coli. | 1. helps AMPs to secret out of E. coli. | ||
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<a href="https://2015.igem.org/Team:TCU_Taiwan/Project/Reference"> • Wound dressing:</a> | <a href="https://2015.igem.org/Team:TCU_Taiwan/Project/Reference"> • Wound dressing:</a> | ||
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Based on AMPs to develop into a potential material of wound dressing. | Based on AMPs to develop into a potential material of wound dressing. |
Revision as of 00:10, 12 August 2015
AMP. coli |
AMPs have an extensive ability in disinfect. Unlike antibiotics, AMPs can puncture the cell membrane to kill the bacteria therefore by passing bacterial antibiotic drug resistance mechanisms. Two kinds of AMPs were selected as our reagents: Epinecidin-1 and Signiferin.
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• Epinecidin-1: 1. from the skin mucus of Epinephelus coioides a kind of fish.
2. has function of killing bacteria.
3. In addition, it has the ability to help wounds healing and has been proven by animal studies.
• Signiferin:
1. from the skin mucus of Crinia signifera a kind of tree frog.
2. have function of killing bacteria.
3. have great ability in disinfect Methicillin-Resistant Staphylococcus aureus (MRSA).
4. had already been kindly proved by the 2013 TU-Delft iGEM team.
2. from Streptomyces lividans to trasport chitinase C to secretion system, which has been proven to work in E.coli by
reference.
Based on AMPs to develop into a potential material of wound dressing.
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Contact us tcutaiwan@gmail.com No.701, Sec. 3, Zhongyang Rd. Hualien 97004, Taiwan |