Team:Paris Bettencourt/Protocols/PCR

PCR protocol (Phusion)
  • Thaw PCR mastermix on ice for 10min.
  • add 2µL of each primers in a PCR tube.
  • add 1uL of the DNA you want to amplify in the same tube.
  • add 25uL of PCR master mix (Phusion).
  • add 20uL of water to the tube.
  • Thermocycling conditions
    • initial denaturation 98°C for 30 seconds
    • 35 cycles
      • 94°C for 30 seconds
      • 57°C for 30 seconds
      • 72°C 30 seconds/kb
    • final extension of 72°C for 10 minutes
    • infinite hold 12°C