Team:NRP-UEA-Norwich/Modeling/3D

3D Modelling Overview

3D models are a fantastic way to show the structure of molecules. We built these models using the SWEET software.

Glycogen

Glycogen is a polysaccharide composed of glucose units linked by alpha 1-4 glycosidic bonds. Each linear chain contains approximately 13 glucose residues and, except of course for the outermost tier of the molecule, carries two branches of the same length that are attached 3–4 residues apart.

Recent studies have suggested that high dietary intake of resistant starch may reduce colon cancer and inflammatory bowel disease. Resistant starches escape digestion in the small intestine and are fermented by microbiota in the colon. A small proportion of these colonic bacteria produce short chain fatty acids including butyrate, which can activate apoptosis in colon cancer cells.

Our project is focused on increasing the amount of butyrate in the colon.

Amylose

Colon cancer is the second most common cause of cancer death with 30,000 new cases diagnosed every year in England and Wales and a registered cause of death in half that number.

Recent studies have suggested that high dietary intake of resistant starch may reduce colon cancer and inflammatory bowel disease. Resistant starches escape digestion in the small intestine and are fermented by microbiota in the colon. A small proportion of these colonic bacteria produce short chain fatty acids including butyrate, which can activate apoptosis in colon cancer cells.

Our project is focused on increasing the amount of butyrate in the colon.

Amylopectin

Colon cancer is the second most common cause of cancer death with 30,000 new cases diagnosed every year in England and Wales and a registered cause of death in half that number.

Recent studies have suggested that high dietary intake of resistant starch may reduce colon cancer and inflammatory bowel disease. Resistant starches escape digestion in the small intestine and are fermented by microbiota in the colon. A small proportion of these colonic bacteria produce short chain fatty acids including butyrate, which can activate apoptosis in colon cancer cells.

Our project is focused on increasing the amount of butyrate in the colon.

References

http://www.biotopics.co.uk/jsmol/glycogen.html

http://watcut.uwaterloo.ca/webnotes/Metabolism/glycogenStructure.html.

"Photonic" and "spintronic" computing is the principle of transferring information by light or electron spin.

Currently, copper wires transfer information in a computer; the process is slowed down as the wires heat up. "Photonic" and "spintronic" computing is the principle of transferring information by light or electron spin.