Team:Birkbeck/InterLab Study/supplementary info

iGEM Westminster Logo




Birkbeck iGEM

The Owligos are the first-ever team entered into the international Genetically Engineered Machine (iGEM) Competition by Birkbeck, University of London. We’re a varied group of students who reflect the diversity and unique character of our institution: many of us have chosen science as a second career, having already spent some time in full-time work. For most of us, this has meant making our way through a degree while continuing to work full-time. Hopefully this kind of dedication will help us successfully navigate our way through our iGEM project.

Project Aim

Our project aims to create a new diagnostic solution that will be low-tech and cost-effective enough to allow its usage in deprived and remote communities. We’re attempting to engineer a bacteriophage lambda chassis to change its host affinity, while simultaneously adding a marker that will facilitate easy detection of a target bacterial pathogen in patient samples.

To demonstrate this approach as a proof of concept for the competition, we plan to change this affinity between different strains of E.coli; however, ultimately we hope to demonstrate that this principle could also be applied to alter the phage’s host range to other bacterial species. We could then provide a modular system capable of diagnosing a range of diseases. Of course, we haven’t chosen a simple goal. But as Birkbeck pioneers, we are determined to prove ourselves by making our project a success. We can’t wait to present the results of our work at the Giant Jamboree in September!




under construction

FluorescenceFluorescence, table, Tukey HSD, 1 layers, 2 levels of column headers and 1 levels of row headers, table with 6 columns and 13 rows
Tukey HSDa
Organism N Subset for alpha = 0.05
1 2 3 4
E. coli DH5 alpha 9 4713.00      
E. coli DH5 alpha negative control 9 6418.56      
E. coli DH5 alpha + P3 9 9511.89      
E. coli DH5 alpha Positive control 9   26818.56    
E. coli DH5 alpha + P2 9     40126.89  
E. coli DH5 alpha + P1 9       74270.33
Sig.   .243 1.000 1.000 1.000
Means for groups in homogeneous subsets are displayed.
a. Uses Harmonic Mean Sample Size = 9.000.