Team:Evry

Hacking the immune system.

EVRY-GENOPOLE IGEM 2015 PROJECT

Our immune system can be seen as a balance between immunity and tolerance. This mechanism sometimes fails and lead to deleterious effects: a too important immune response can lead to food allergies or IBD. Absence of an immune response, in the other hand, plays a role in the spread of cancer cells.

Dentrictic cells can orchestrate the immune response. By acting on them using engineered micro-organisms, we want to induce or repress the immune response when the immune system fails.

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