Introduction
1 Resistance
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At first, it will be acid ressistant, to survive in stomach’s acidic microenvironment!
2 Repellency
Secondly, as Wile E. coli needed to find its way properly, he now has a part for targeting Helico
Runner; chemotaxis part!
3 Motility
Thirdly, we had to make sure Wile E. Coli reached to Helico Runner, so now it can penetrate into the
mucos layer with its faster flagellas!
4 Sensing
The fourth part And gate, is designed to make Wile E. Coli sensing Helico Runner. Look! It’s not
chasing the fake Helico Runner anymore!
5 Killing
Thanks to our fifth part, Wile E. Coli can destroy Helico Runner with the antimicrobial peptide
Pexiganan. Revenge time!
Cancer
Oh wait, what if gastric ulcer causes gastric cancer? How will we open this cancer door to reach and
cure it?
miRNA Switch
Here is the solution; miRNA switch! Mr. exosome has a key to open the door now. Just like key
matches the lock, if miRNAs match the switch we can target cancer more specifically now!
-the end-