Team:Oxford/Team
team
Kyle
Bennett
Biochemistry
I’ve been responsible for the designs behind the kill switches. I’ve contributed in the wet lab, mainly in molecular cloning, and in particular, with the Synbiota parts. Additionally, I’ve been active in our outreach part of the project, making presentations for GCSE students, and writing our blog.
Helen
Brown
Biochemistry
I’ve been working on considerations of project safety, including physical containment and kill switch options, as well as ensuring that lab practices follow the safety protocols outlined by our demonstrator. I’ve also been in the wet lab, focussing mainly on molecular cloning. I’ve helped in outreach as well, helping to create presentations for summer schools, and helping to promote our project on social media. Finally, I’ve helped to code up the wiki.
Ria
Dinsdale
Chemistry
As chief chemist I have been in charge of making beads to encapsulate the bacteria (and vodka) as well as having far too much fun making up litres and litres of fluorescent solutions. I have been part of the interface between the wet-lab and the modeling by producing experimental data on the diffusion rates out of the beads. Along with my time in the wet-lab I have contributed to ensuring all of our content is coded up for the wiki; as well as taking artsy pictures for the headers.
George
Driscoll
Biochemistry
Silas
Elliot
Biology
I've been involved mostly with outreach and public engagement. This has been through the production of videos and visits to a local hospital. I've also been part of the day to day work in the wetlab, as well as helping design assets for the poster, presentation and wiki.
James
Fage
Biology
As our friendly neighbourhood biologist I’ve been looking into how our final product might interact with the ecology of the urinary tract microbiome and the immune system, as well as whether such problems might be tractable within the scope of our project. I have also been working regularly in the wet-lab, with my focus being on toxicity and biofilm assays.
June Juyeon
Han
Biochemistry
I’ve been mainly working on culture and image taking of interlab fluorescence microscopy, as well as loading fluorescence and toxicity 96 well assay and retrieving data for them. I have helped in policy & practice section of our project by contacting and meeting synthetic biology experts to comment on our project.
Henry
Howard-Jenkins
Engineering
I am a member of the modeling duo and have designed and built our team's wiki. Working in the shadow of Will, star of viral sensation; Modeling with Will, I have been producing gene-expression and diffusion models. Additionally, I have helped with outreach and interviews for our practices section.
Raphaella
Hull
Biochemistry
Leon
Kong
Chemistry
Lychee
Lu
Biochemistry
When not growing on trees, I am usually somewhere in the lab running microscopy and plate reader experiments for the interlab study and processing the subsequent data. Have also attempted to make contact with teams in other countries for collaboration efforts; these attempts bore fruits on a few occasions as can be viewed on our collaborations page.
Duke
Quinton
Biochemistry
Over the summer I have been working regularly in the wet lab, particularly on cloning procedure and Western Blotting. I have been writing articles for our blog page, including a piece on the first GM human embryo. I have designed our project poster, as well as coded various elements of the wiki. My favourite outreach experience was talking to UNIQ summer school, and seeing what they thought of our project!
Will
Van Duzer
Physics
Mabel
Wong
Biochemistry
Thanks to lab experience prior to iGEM, I was the team’s chief molecular cloner. In between wet lab commitments, I made initial contact with local hospitals, helped teach 17 year-olds about synthetic biology at the UNIQ summer school workshop and successfully avoided learning how to code. This inability to code however did culminate in being on BBC Radio for a grand total of 7 minutes on the day of the lab’s electrical shutdown.
Advisors
Dr George
Wadhams
Supervisor
George Wadhams’ research interests lie in how bacteria sense and integrate environmental information. His group focuses on understanding in a quantitative manner how multiple, homologous pathways operate in individual cells and how the components of these pathways can be used to create synthetic pathways.
Dr Chris
Jones
Supervisor
For optimum growth bacteria must adapt to their environment, one way to do this is by moving towards advantageous conditions. To do this they must be able to both move and to control the direction of that movement. The signaling pathways that control this directionality form into large arrays of receptors and kinases. The best studied arrays contain transmembrane receptors, however many species also contain arrays that are non-transmembrane and therefore in the cytoplasm. My work focuses on the cytoplasmic chemoreceptor array of Rhodobacter sphaeroides. Looking at both how the array is formed and stabilised without the presence of a membrane and how the array is split and segregated prior to cell division insuring faithful inheritance of the complete chemotaxis pathway.
Professor Judy
Armitage
Advisor
Judy Armitage is interested in the dynamics of bacterial sensory transduction and the control of bacterial motility. In particular, her research group focuses on the communication between the sensory and adaption mechanisms of the two pathways as a model for sensory network integration in general..
Professor Anthony
Watts
Advisor
Anthony Watts’ group is devising solid state NMR methods for determining high-resolution details of information-rich sites within membrane receptors. Recent focus has been on the neurotensin receptor (NTS1), which is now available highly purified and monodispersed in detergent as well as in a ligand-binding form.
Professor Antonis
Papachristodoulou
Advisor
Antonis Papachristodoulou’s research interests include systems and synthetic biology, network systems, aerospace systems and flow control, and convex optimisation. Furthermore, he works on modern control theory, robust stability analysis and design, as well as nonlinear dynamical systems and Lyapunov stability.
Andreas
Harris
Advisor
Andreas Harris works on the design and implementation of gene regulatory networks harnessing feedback to increase robustness and tunability. The designs are based around transcriptional networks and attempt to translate well-understood control modules, such as proportional and integral controllers, to biological systems.
