Team:MIT/ModelingCHutch
Project
Dynamic Flux Balance Analysis
C. Hutchinsonii Model Development
E. Coli Model Development
Coculture Simulations and Conclusions
C. Hutchinsonii Model Development
E. Coli Model Development
Coculture Simulations and Conclusions
C. hutchinsonii Model Development
In order to implement a dFBA model for $$\textit{C. hutchinsonii}$$, we obtained a valid whole-genome scale model with its central metabolism, inserted reactions for cellulose degradation into it, fitted parameters for cellulose degradation and nutrient uptake to get more realistic behavior, and ran pure culture simulations.
Obtaining a whole-genome scale metabolic model for C. hutchinsonii
$$
\ce{C6H5-CHO}
$$
$$\textit{C. hutchinsonii}$$
Modeling Cellulose Degradation
Parameter Fitting
dFBA Simulation of a Pure Culture of C. hutchinsonii
