Team:UNAM-CU/Collaborations

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Collaborations

We made a collaboration with the UNAH iGEM team from Honduras, they are working on a project to fight Dengue, so we decided to help them with their project in the modeling and wetlab parts; for this purpose we designed a working plan to help a part of their team to get started. We also gave them the opportunity to present their project to researchers of the UNAM from physiology, biotechnology, genomic science and medicine areas. They came to Mexico and worked 4 weeks in June in the institutes of chemistry, physiology and in the faculties of science and medicine.

Modeling area.

The section of our team who was more devoted to board mathematical modeling decided to give a course to our guests on the general ideas for developing a mathematical model, in order to do this, a 5-days system was implemented.

• The first day was devoted to general problem solving, presenting some problems of mathematical logic, while trying to maintain a biological related subject in the problems, some of the listeners seemed enthusiastic with this idea and even used some extra time to discuss more problems. The computing part focused on principles of programing and getting to know the commands.
• The second day was used to present a general idea on how functions work, in order to avoid confusions while working on derivatives and forming a solid basis for next few days.The computing part focused on first problems and starting to make their own programs.
• We began the third day with a demonstration on derivatives and how they express change, which is a powerful weapon on biological systems modeling.The computing part focused on how to program the derivatives and some basic biological problems.
• Once the listeners were comfortable with this kind of equations, some general models of this kind were discussed, for this purpose, we asked for systems that they thought that could be analyzed under this perspective.The computing part focused on how to program models using our own as an example, after that we started programing the first drafts of their model.
• On the last day, it was decided to present some other branches of mathematics that are also useful in actual biology, like game theory or graph theory, with useful examples on how they work in different biological systems. We continued programing their model draft and trying different simulations to get the best results.

Wetlab work

They were taught on the basics of molecular biology, competent cells, growing mediums, pcr, transformations and bioinformatics on how to design their biobrick. The focus here was on the direct wet lab work, we use space in the Chemistry institute for this classes.

The feedback was good and they felled confident on being able to continue their work back on their home country.

Project presentation

The team got a space to present their project on the IBT ( Institute of Biothecnology), CCG ( Center of Genomic Science), IQ ( Chemistry Institute), IFC (Institue of Celullar Physiology. They present it in group seminar or in special apointments with the researchers, they got feedback and learned of ways to improve their project and biobricks. The researchers where

• Dr. Rafael Peña

• Dra. Laura Palomares

• Dr. Julio Freyre

• Dr. Gerardo Corzo.

• Dr. Ayari Fuentes

• Dr. Maximino Aldana

• M in B. Jose Alonso.

• Dr. Enrique Amador Guzmán

• Dra. Gloria Gutiérrez Venegas.

• Dr. David Romero.