Team:NJAU China

IGEM

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Abstract

Project Description

In this project, we try to complete a simulation of memorizer. Nowadays, the most cellular memories are limited to protein levels, which are transient, instantaneous and inapparent. We designed a system to achieve the storage of information by a transient stimulation but use a long-lasting response. The two processes are divided into two bacterial community, the “Recorder” and the “Saver”, which complete their information exchange by conjugation. And in order to realize the memory erasure, we use the CRISPR-Cas9 system in the “Saver” when they receive a specific signal. By design such a cellular memory technology, we make a bacterial memory storage device. And together with biological transistor and other bio-electronic component, we can preview the prototype of the biological computer ^[1] .

Description [Figure 2.1.2].

Chemical reactions:

Process:

2FeS₂(s) = 2Fe²⁺(aq) + 4SO₄²⁻(aq)

Refrences:

[1] Rensing, C., & Grass, G. (2003). Escherichia coli mechanisms of copper homeostasis in a changing environment. FEMS microbiology reviews,27(2‐3), 197-213.