Welcome to CGU_Taiwan Wik page

Oral squamous cell carcinoma(OSCC)is a common cancer worldwide.One of the major problems of OSCC is that early malignancy could only be detected by clinical oral examination from health care professionals, and there are on clinical tests at the molecular level. Recently, there are several RNAs and proteins reported as promising potential noninvasive biomarkers in saliva for OSCC. Our team plans to establish simple and quantifiable detection methods for those biomarkers. Our system includes two arms:
1)synthetic toehold switch gene regulators as RNA sensors to detect specific mRNA biomarkers
2)engineered yeasts that express a reporter activated by IL-8, which is one of the most statistically significant protein biomarkers in OSCC saliva samples
These efforts will provide the groundwork for new molecular diagnoses in OSCC.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~