Team:Aalto-Helsinki/Kinetics

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Kinetics

General

AtoB

Constant	Value	Source	To note
\( K_{cat}^{AtoB} \)	0.001 jtn	link	Forward reaction
\( K_{M}^{AtoB:Acetyl\text{-}CoA} \)	0.001 jtn	link	Is there something special about this?

FadB2

Constant	Value	Source	To note
\( K_{cat}^{FadB2} \)	0.001 jtn	link	Forward reaction
\( K_{cat}^{FadB2} \)	0.001 jtn	link	Reverse reaction
\( K_{M}^{FadB2:Acetoacetyl\text{-}CoA} \)	0.001 jtn	link	Forward reaction
\( K_{cat}^{FadB2:NADPH} \)	0.001 jtn	link	Forward reaction
\( K_{cat}^{FadB2:3\text{-}Hydroxybutyryl\text{-}CoA} \)	0.001 jtn	link	Reverse reaction
\( K_{cat}^{FadB2:NADP^+} \)	0.001 jtn	link	Reverse reaction

Hdb

Constant	Value	Source	To note
\( K_{cat}^{Hdb} \)	336.4 1/min	link	Forward reaction
\( K_{M}^{Hdb:Acetoacetyl\text{-}CoA} \)	5e-5 mol/l	link	Is there something special about this?
\( K_{M}^{Hdb:NADPH} \)	7e-5 mol/l	link	Is there something special about this?

Crt

Constant	Value	Source	To note
\( K_{cat}^{Crt} \)	1310.8 1/min	link	Forward reaction
\( K_{M}^{Crt:3\text{-}Hydroxybutyryl\text{-}CoA} \)	3e-5 mol/l	link	Is there something special about this?

Ter

Constant	Value	Source	To note
\( K_{cat}^{Ter} \)	1881.6 1/min	link	Forward reaction
\( K_{M}^{Ter:Crotonyl\text{-}CoA} \)	2.7e-06 mol/l	link	Is there something special about this?
\( K_{M}^{Ter:NADH} \)	5.2e-06 mol/l	link	Is there something special about this?
\( K_{I}^{Ter:Butyryl\text{-}CoA} \)	1.98e-07 mol/l	link	Is there something special about this?

YciA

Constant	Value	Source	To note
\( K_{cat}^{YciA} \)	1320 1/min	link	Forward reaction
\( K_{M}^{YciA:Butyryl\text{-}CoA} \)	3.5e-06 mol/l	link	Is there something special about this?

Car

Constant	Value	Source	To note
\( K_{cat}^{Car} \)	150 1/min	link	Forward reaction
\( K_{M}^{Car:Butyrate} \)	0.013 mol/l	link	Is there something special about this?
\( K_{M}^{Car:NADPH} \)	4.8e-05 mol/l	link	Is there something special about this?
\( K_{I}^{Car:ATP} \)	0.000115 mol/l	link	Is there something special about this?

Sfp

Ado

Constant	Value	Source	To note
\( K_{cat}^{Ado} \)	0.215 1/min	link	Forward reaction
\( K_{M}^{Ado:Butyraldehyde} \)	0.0101 mol/l	link	Is there something special about this?

Constants

This is a table of already known typical concentrations in a cell that we use in our model.

Constant	Value	Source	To note
[Acetyl-CoA]	0.00061 mol/l	link	Is there something special about this?
[Acetoacetyl-CoA]	2.2e-05 mol/l	link	Is there something special about this?
[CoA]	0.00014 mol/l	link	Is there something special about this?
[NADPH]	00012 mol/l	link	Is there something special about this?
[NADP\( ^+\)]	2.1e-06 mol/l	link	Is there something special about this?
[NADH]	8.3e-05 mol/l	link	Is there something special about this?
[NAD\( ^+\)]	0.0026 mol/l	link	Is there something special about this?
[ATP]	0.0096 mol/l	link	Is there something special about this?
[AMP]	0.00028 mol/l	link	Is there something special about this?
[H\( _2\)O]	38.85 mol/l	link	Is there something special about this?