Difference between revisions of "Team:EPF Lausanne/Practices"

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       <p>As we wanted them to understand all the aspect of what a "classic iGEM summer" felt like we prepared three different activities :
 
       <p>As we wanted them to understand all the aspect of what a "classic iGEM summer" felt like we prepared three different activities :
       <h5>mini iGEM</h5>
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       <h4>mini iGEM</h4>
As we wanted them to truly understand the iGEM competition we held a mini iGEM competition. In this activity, small groups of students worked together to create igem projects they would present to other teams. They were asked to think about feasability, utility, safety and ethics. During the brainstorming, each team was coached by one of our team. We introduced them to concepts of kill switch, biobricks, motility, transcription pathways, transporters and bio-informatics. We found that the ideas they brought were very smart and imaginative. Some teams even came up with projects that had already been realised in previous iGEM competitions.<h5>Lab immersion<h5><p>Even the most renownd scientist started by pipetting water, this is why we prepared a few activites in the lab to let the students see how it is to work in the world of synthetic biology.[insert activities]</p><h5>Ethics debate<h5><p>Lastly, ethics is really important in the field of Sciences. The missuse of novel technologies is a matter that every scientist with integrity has to think about. To make the students reflect about actions and consequences we prepared an ethics debate during which we gave the students a role to defend. We gave them these roles because we wanted them to be able to think about another opinion and it was great to see them get into the role and having fun doing so. At the end of the debate we exited the roles and were pleased to see that what we did opened their eyes on different aspects concerning the responsability that we have concerning the research. [maybe talk about swiss votation system?]</p>
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As we wanted them to truly understand the iGEM competition we held a mini iGEM competition. In this activity, small groups of students worked together to create igem projects they would present to other teams. They were asked to think about feasability, utility, safety and ethics. During the brainstorming, each team was coached by one of our team. We introduced them to concepts of kill switch, biobricks, motility, transcription pathways, transporters and bio-informatics. We found that the ideas they brought were very smart and imaginative. Some teams even came up with projects that had already been realised in previous iGEM competitions.<h4>Lab immersion<h4><p>Even the most renownd scientist started by pipetting water, this is why we prepared a few activites in the lab to let the students see how it is to work in the world of synthetic biology.[insert activities]</p><h4>Ethics debate<h4><p>Lastly, ethics is really important in the field of Sciences. The missuse of novel technologies is a matter that every scientist with integrity has to think about. To make the students reflect about actions and consequences we prepared an ethics debate during which we gave the students a role to defend. We gave them these roles because we wanted them to be able to think about another opinion and it was great to see them get into the role and having fun doing so. At the end of the debate we exited the roles and were pleased to see that what we did opened their eyes on different aspects concerning the responsability that we have concerning the research. [maybe talk about swiss votation system?]</p>
  
 
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Revision as of 16:41, 11 September 2015

EPFL 2015 iGEM bioLogic Logic Orthogonal gRNA Implemented Circuits EPFL 2015 iGEM bioLogic Logic Orthogonal gRNA Implemented Circuits

Practices

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Highschool students' visit

Start of the day

Since iGEM is encouraging young students to get into the lab, think about innovative ideas using Synthetic Biology we wanted to get this thinking into highschool students. To do so, we contacted three different highschools in our reagion. [insert name of highshcool], [insert name of highshcool] and [insert name of highshcool] gladly sent us students interested in biology and eager to find out about synthetic biology.

Indeed, we found out that, even if the level of biology is fairly high in Switzerland, the learned material doesn't include synthetic biology. Our goal for that day was that these students would have a new view of the field of biology and that even engineers should be interested in this field, that we can hack life!

Joseph_Cyril_Nina depart
Cyril Presentation

Presentation

We welcomed the students with a presentation that had three parts. The first one was about iGEM, the modalities and principles of the competition, the number of participating teams, the contribution of each team, etc. The second part was about synthetic biology and, after introducing them about common lab techniques and procedures, we talked about the third part, our « BioLOGIC » project.

After the presentation we dispatched them into three groups for three different activities


mini_iGEM
mini_iGEM
mini_iGEM

As we wanted them to understand all the aspect of what a "classic iGEM summer" felt like we prepared three different activities :

mini iGEM

As we wanted them to truly understand the iGEM competition we held a mini iGEM competition. In this activity, small groups of students worked together to create igem projects they would present to other teams. They were asked to think about feasability, utility, safety and ethics. During the brainstorming, each team was coached by one of our team. We introduced them to concepts of kill switch, biobricks, motility, transcription pathways, transporters and bio-informatics. We found that the ideas they brought were very smart and imaginative. Some teams even came up with projects that had already been realised in previous iGEM competitions.

Lab immersion

Even the most renownd scientist started by pipetting water, this is why we prepared a few activites in the lab to let the students see how it is to work in the world of synthetic biology.[insert activities]

Ethics debate

Lastly, ethics is really important in the field of Sciences. The missuse of novel technologies is a matter that every scientist with integrity has to think about. To make the students reflect about actions and consequences we prepared an ethics debate during which we gave the students a role to defend. We gave them these roles because we wanted them to be able to think about another opinion and it was great to see them get into the role and having fun doing so. At the end of the debate we exited the roles and were pleased to see that what we did opened their eyes on different aspects concerning the responsability that we have concerning the research. [maybe talk about swiss votation system?]

mini_iGEM
mini_iGEM
mini_iGEM

Mini iGEM projects

Name Description
Famousse Famousse ("Mousse" means foam in french) is a gun that sprays an isolating material to fill walls. The fluid consists of bacterias that produce foam once in contact with oxygen and of yeasts that make CO2 holes in the foam. After a while, the foam solidifies and bacterias and yeasts die by apoptosis: the isolating material is finished.
RIDG pill The RIDG pill (Régulateur intelligent Des Graisses or Intelligent Fat Regulator, IFR pill) is made out of bacteria that detect, once in the intestine, if the person suffers of obesity or anorexia thanks to hormone receptors. In case of obesity, the bacteria would respond to that input by secreting proteins that block lipid transporters in epithelial cells. In case of anorexia, the bacteria would secrete hormones that would make epithelial cells create more lipid transporters.
PestiBac Bacteria substituting pesticides. These bacteria live on the leaves of the plants and secrete repelling substances. These bacteria have sensor in order to die if not in contact with the target plant or if they came in contact with animal's saliva. In addition they are modified to have a shorter lifetime, in order to limit population growth.
Luciolight Luciolight is a Street Lamp made out of bacteria that imit biological circuit of fireflies.
Bacteriolavage Bacteriolavage is a bacterial washing system to clean clothes with less water waste. Bacteria synthesize enzymes that degrade lipids and sugars in smaller particles that are more water-soluble, so that less water is consumed. Students used the concept of magnetic bacteria developed by the 2014 iGEM Berlin team to efficiently remove bacterias from clothes once the wash was finished.
Killpilus Killpilus is a permanent hair removal cream. Bacterias contained in the preparation kill hair follicle stem cells. The team looked up on the internet for receptors specifically expressed in those stem cells to avoid off targets. For safety reasons, bacterias would commit suicide by apoptosis after one hour.
ConchitaColi ConchitaColi cells digest dust and produce scented molecules. After the washing is finished, bacterias move towards a luminous bin where they die by apoptosis.
Healing+ "Healing+" is a system to repair wounds. Mammalian cells circulating in the blood detect intrusion of pathogens and respond by mobilisation of collagen and platelets in wounds.
easyFer "easyFer" ("easyIron") is a system that uses an iron detecting biosensor to simplify the iron detection in the blood.

EPFL 2015 iGEM bioLogic Logic Orthogonal gRNA Implemented Circuits

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