Difference between revisions of "Team:Columbia NYC"

 
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<h2> Project Overview </h2>
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<a href= "https://2015.igem.org/Team:Columbia_NYC"> <img src="https://static.igem.org/mediawiki/2015/c/ca/Columbia_NYC_Logo.jpg" alt="Columbia iGEM Logo" style="width:100%"> </a>
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<a href = "#"> <li> THE PROJECT
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<a href = "https://2015.igem.org/Team:Columbia_NYC/Description"> <li> DESCRIPTION </li></a>
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<a href = "https://2015.igem.org/Team:Columbia_NYC/Design"> <li> DESIGN </li></a>
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<a href = "https://2015.igem.org/Team:Columbia_NYC/Experiments"> <li> EXPERIMENTS </li></a>
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<a href = "https://2015.igem.org/Team:Columbia_NYC/Results"> <li> RESULTS </li></a>
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<a href = "https://2015.igem.org/Team:Columbia_NYC/Team"> <li> TEAM MEMBERS </li></a>
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<a href = "https://2015.igem.org/Team:Columbia_NYC/Parts"> <li> TEAM PARTS </li></a>
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<a href="https://2015.igem.org/Team:Columbia_NYC/Notebook"><li> THE NOTEBOOK </li></a>
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<a href = "https://2015.igem.org/Team:Columbia_NYC/Attributions"> <li> ATTRIBUTIONS </li></a>
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<a href = "https://2015.igem.org/Team:Columbia_NYC/Collaborations"><li> COLLABORATIONS </li></a>
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<a href = "https://2015.igem.org/Team:Columbia_NYC/Practices"><li> HUMAN PRACTICE </li></a>
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<a href="https://2015.igem.org/Team:Columbia_NYC/Safety"><li> LAB SAFETY </li></a>
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<a href = "https://2015.igem.org/Team:Columbia_NYC/Sponsors"> <li> OUR SPONSORS </a>
  
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<p> Our ultimate goal is to design a template for the establishment of a consortia of engineered bacteria whose individual component can effectively communicate with one another. From an abstract perspective, this collection of biological parts and circuits is essentially a biological computer that can perform algorithms by processing information and generating an output. From a practical perspective, such a system will allow individual cell types to have specific roles that allow for the division of labor, much like the specialization of cells in multi-cellular organisms. However, such a broad goal is quite expansive and not appropriate for the time frame of an iGEM project; as such, we narrowed the scope of the project to focus on establishing such a consortia of bacteria for the organized secretion of gut-peptides in probiotic cells that will work in tandem with the natural gut-flora to help modulate and regulate hormonal activities in humans - thereby providing a therapeutic system that is adaptive to the environment of the host. </p>
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<p> The key components to such a system are inter- & intra- cellular communications and a platform for the release of peptides from the cell. In order to design a system with a practical purpose and further refine our goals, the team focused on a design that could potentially combat obesity and diabetes by utilizing the following gut peptides: </p>  
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<h4 style = "font-size: 50px; top: 10%; left: 25%; color: white; width: 1000px;"> Welcome to Columbia iGEM </h4>
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<li> Glucagon-Like Peptide-1 (GLP-1): Enhances the secretion of insulin  </li>
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<li> Peptide YY (PYY): Down-regulates appetite  </li>
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<li> Ghrelin: Up-regulates appetite </li>
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Latest revision as of 02:48, 19 September 2015