Difference between revisions of "Team:Cairo Egypt"

 
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<html>
 
<html>
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<link rel="stylesheet" href="https://2015.igem.org/Team:Cairo_Egypt/core/default_style_remover?action=raw&amp;ctype=text/css" type="text/css">
 
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<h2> Welcome to iGEM 2015! </h2>
 
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<p>Your team has been approved and you are ready to start the iGEM season! </p>
 
  
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<h4>Before you start: </h4>
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<meta http-equiv="cache-control" content="max-age=0" />
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<p> Please read the following pages:</p>
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<meta http-equiv="cache-control" content="no-cache" />
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<ul>
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<meta http-equiv="expires" content="0" />
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<li>  <a href="https://2015.igem.org/Requirements">Requirements page </a> </li>
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<meta http-equiv="expires" content="Tue, 01 Jan 1980 1:00:00 GMT" />
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<li> <a href="https://2015.igem.org/Wiki_How-To">Wiki Requirements page</a></li>
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<meta http-equiv="pragma" content="no-cache" />
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</ul>
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<div class="highlightBox">
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<script>
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<h4> Styling your wiki </h4>
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document.styleSheets[0].disabled = true
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<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
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</script>
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<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>
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</div>
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<h4> Editing your wiki </h4>
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<link rel="stylesheet" href="https://2015.igem.org/Team:Cairo_Egypt/css/igem_toolbar_style?action=raw&ctype=text/css" type="text/css">
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<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>  
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<link rel="stylesheet" href="https://2015.igem.org/Team:Cairo_Egypt/css/bootstrap?action=raw&ctype=text/css" type="text/css">
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<p> <a href="https://2015.igem.org/wiki/index.php?title=Team:Cairo_Egypt&action=edit"> Click here to edit this page! </a></p>
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<link rel="stylesheet" href="https://2015.igem.org/Team:Cairo_Egypt/css/home_style?action=raw&ctype=text/css" type="text/css">
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<p>See tips on how to edit your wiki on the <a href="https://2015.igem.org/TemplatesforTeams_Code_Documentation">Template Documentation</a> page.</p>  
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<link rel="stylesheet" href="https://2015.igem.org/Team:Cairo_Egypt/css/custom?action=raw&ctype=text/css" type="text/css">
  
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<!-- fonts -->
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<link rel="stylesheet" href="//maxcdn.bootstrapcdn.com/font-awesome/4.3.0/css/font-awesome.min.css">
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<link href="http://fonts.googleapis.com/css?family=Source+Sans+Pro:300,400,700,300italic,400italic,700italic" rel="stylesheet" type="text/css">
  
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<h4>Templates </h4>
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<!-- Navigation -->
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<p> This year we have created templates for teams to use freely. More information on how to use and edit the templates can be found on the
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    <a id="menu-toggle" href="#" class="btn btn-dark btn-lg toggle"><i class="fa fa-bars"></i></a>
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<a href="https://2015.igem.org/TemplatesforTeams_Code_Documentation">Template Documentation </a> page.</p>  
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    <nav id="sidebar-wrapper">
 +
        <ul class="sidebar-nav">
 +
            <a id="menu-close" href="#" class="btn btn-light btn-lg pull-right toggle"><i class="fa fa-times"></i></a>
 +
            <li class="sidebar-brand">
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                <a href="#top"  onclick = $("#menu-close").click(); >Project ABC</a>
 +
            </li>
 +
            <li>
 +
                <a href="#top" onclick = $("#menu-close").click(); >Home</a>
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            </li>
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            <li>
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                <a href="#about" onclick = $("#menu-close").click(); >About</a>
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            </li>
 +
            <li>
 +
                <a href="#services" onclick = $("#menu-close").click(); >What we have</a>
 +
            </li>
 +
            <li>
 +
                <a href="#contact" onclick = $("#menu-close").click(); >Contact</a>
 +
            </li>
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        </ul>
 +
    </nav>
  
 +
    <!-- Header -->
 +
    <header id="top" class="header">
 +
        <div class="text-vertical-center">
 +
            <h1>Project ABC</h1>
 +
            <h3>Cairo | Egypt Team</h3>
 +
            <br>
 +
            <a href="#about" class="btn btn-dark btn-lg">Find Out More</a>
 +
        </div>
 +
    </header>
 +
 +
    <!-- About -->
 +
    <section id="about" class="about">
 +
        <div class="container">
 +
            <div class="row">
 +
                <div class="col-lg-12 text-center">
 +
                    <h2>Brief Description</h2>
 +
                    <p class="lead">Breast cancer is the most common malignancy in women and constitutes 18% of all female cancers (Jemal et al., 2002) Although there has been a slight decrease in mortality in breast cancer patients (Schiffman et al., 2002), it is not uncommon for even early-stage breast cancer to metastasize. Therefore, novel therapeutic strategies are constantly being pursued (Bange et al., 2001). It has been reported that some bacterial species preferentially replicate and accumulate within tumors. At critical cell densities, the binding of a regulator protein to the signal leads to the switch on of genes controlled by QS and therefore a coordinated population response Moreover, they possess certain advantageous features such as motility, capacity to simultaneously carry and express multiple therapeutic proteins. Its elimination by antibiotics makes it a promising new strategy in cancer treatment. Azurin is a copper-containing redox protein with low molecular Weight which can efficiently induce cell apoptosis by raising the intracellular levels of p53 and Bax. It has been found that Azurin receptors are hyper expressed on the surfaces of cancer cells relative to their expression on the surfaces of normal cells. We do intend to modify genetic material of bacteria species that localize and induce expression of Azurin in presence of tumor only.</p>
 +
                </div>
 +
            </div>
 +
            <!-- /.row -->
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        </div>
 +
        <!-- /.container -->
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    </section>
 +
 +
    <!-- Services -->
 +
    <!-- The circle icons use Font Awesome's stacked icon classes. For more information, visit http://fontawesome.io/examples/ -->
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    <section id="services" class="services bg-primary">
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        <div class="container">
 +
            <div class="row text-center">
 +
                <div class="col-lg-10 col-lg-offset-1">
 +
                    <h2>What we have</h2>
 +
                    <hr class="small">
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                    <div class="row">
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                        <div class="col-md-3 col-sm-6">
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                            <div class="service-item">
 +
                                <span class="fa-stack fa-4x">
 +
                                <i class="fa fa-circle fa-stack-2x"></i>
 +
                                <i class="fa fa-group fa-stack-1x text-primary"></i>
 +
                            </span>
 +
                                <h4>
 +
                                    <strong>Team</strong>
 +
                                </h4>
 +
                                <p>Learn more about the team and the instructors.</p>
 +
                                <a class="btn btn-light" href="https://2015.igem.org/Team:Cairo_Egypt/Team">Learn More</a>
 +
                            </div>
 +
                        </div>
 +
                        <div class="col-md-3 col-sm-6">
 +
                            <div class="service-item">
 +
                                <span class="fa-stack fa-4x">
 +
                                <i class="fa fa-circle fa-stack-2x"></i>
 +
                                <i class="fa fa-file-text-o fa-stack-1x text-primary"></i>
 +
                            </span>
 +
                                <h4>
 +
                                    <strong>Description</strong>
 +
                                </h4>
 +
                                <p>Learn more about project and results.</p>
 +
                                <a href="https://2015.igem.org/Team:Cairo_Egypt/Description" class="btn btn-light">Learn More</a>
 +
                            </div>
 +
                        </div>
 +
                        <div class="col-md-3 col-sm-6">
 +
                            <div class="service-item">
 +
                                <span class="fa-stack fa-4x">
 +
                                <i class="fa fa-circle fa-stack-2x"></i>
 +
                                <i class="fa fa-flask fa-stack-1x text-primary"></i>
 +
                            </span>
 +
                                <h4>
 +
                                    <strong>Experiments</strong>
 +
                                </h4>
 +
                                <p>Learn more about project and experiments and protocols.</p>
 +
                                <a href="https://2015.igem.org/Team:Cairo_Egypt/Experiments" class="btn btn-light">Learn More</a>
 +
                            </div>
 +
                        </div>
 +
                        <div class="col-md-3 col-sm-6">
 +
                            <div class="service-item">
 +
                                <span class="fa-stack fa-4x">
 +
                                <i class="fa fa-circle fa-stack-2x"></i>
 +
                                <i class="fa fa-bar-chart fa-stack-1x text-primary"></i>
 +
                            </span>
 +
                                <h4>
 +
                                    <strong>Results</strong>
 +
                                </h4>
 +
                                <p>Learn more about project and results.</p>
 +
                                <a href="https://2015.igem.org/Team:Cairo_Egypt/Results" class="btn btn-light">Learn More</a>
 +
                            </div>
 +
                        </div>
 +
                        <div class="col-md-3 col-sm-6">
 +
                            <div class="service-item">
 +
                                <span class="fa-stack fa-4x">
 +
                                <i class="fa fa-circle fa-stack-2x"></i>
 +
                                <i class="fa fa-gears fa-stack-1x text-primary"></i>
 +
                            </span>
 +
                                <h4>
 +
                                    <strong>Parts</strong>
 +
                                </h4>
 +
                                <p>Know more about parts here used in the project.</p>
 +
                                <a href="https://2015.igem.org/Team:Cairo_Egypt/Parts" class="btn btn-light">Learn More</a>
 +
                            </div>
 +
                        </div>
 +
                        <div class="col-md-3 col-sm-6">
 +
                            <div class="service-item">
 +
                                <span class="fa-stack fa-4x">
 +
                                <i class="fa fa-circle fa-stack-2x"></i>
 +
                                <i class="fa fa-futbol-o fa-stack-1x text-primary"></i>
 +
                            </span>
 +
                                <h4>
 +
                                    <strong>Practices</strong>
 +
                                </h4>
 +
                                <p>Learn more about human practice here.</p>
 +
                                <a href="https://2015.igem.org/Team:Cairo_Egypt/Practices" class="btn btn-light">Learn More</a>
 +
                            </div>
 +
                        </div>
 +
                        <div class="col-md-3 col-sm-6">
 +
                            <div class="service-item">
 +
                                <span class="fa-stack fa-4x">
 +
                                <i class="fa fa-circle fa-stack-2x"></i>
 +
                                <i class="fa fa-book fa-stack-1x text-primary"></i>
 +
                            </span>
 +
                                <h4>
 +
                                    <strong>Notebook</strong>
 +
                                </h4>
 +
                                <p>Know more about agenda and what was done.</p>
 +
                                <a href="https://2015.igem.org/Team:Cairo_Egypt/Notebook" class="btn btn-light">Learn More</a>
 +
                            </div>
 +
                        </div>
 +
                        <div class="col-md-3 col-sm-6">
 +
                            <div class="service-item">
 +
                                <span class="fa-stack fa-4x">
 +
                                <i class="fa fa-circle fa-stack-2x"></i>
 +
                                <i class="fa fa-smile-o fa-stack-1x text-primary"></i>
 +
                            </span>
 +
                                <h4>
 +
                                    <strong>Attributions</strong>
 +
                                </h4>
 +
                                <p>Know who did what in this project from the beginning</p>
 +
                                <a href="https://2015.igem.org/Team:Cairo_Egypt/Attributions" class="btn btn-light">Learn More</a>
 +
                            </div>
 +
                        </div>
 +
                        <div class="col-md-3 col-sm-6">
 +
                            <div class="service-item">
 +
                                <span class="fa-stack fa-4x">
 +
                                <i class="fa fa-circle fa-stack-2x"></i>
 +
                                <i class="fa fa- fa-comments-o fa-stack-1x text-primary"></i>
 +
                            </span>
 +
                                <h4>
 +
                                    <strong>Collaborations</strong>
 +
                                </h4>
 +
                                <p>We contacted some teams, see them here</p>
 +
                                <a href="https://2015.igem.org/Team:Cairo_Egypt/Collaborations" class="btn btn-light">Learn More</a>
 +
                            </div>
 +
                        </div>
 +
<div class="col-md-12 col-sm-12">
 +
<div id="carousel-example-generic" class="carousel slide" data-ride="carousel">
 +
  <!-- Indicators -->
 +
  <ol class="carousel-indicators">
 +
    <li data-target="#carousel-example-generic" data-slide-to="0" class="active"></li>
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    <li data-target="#carousel-example-generic" data-slide-to="1"></li>
 +
    <li data-target="#carousel-example-generic" data-slide-to="2"></li>
 +
   
 +
  </ol>
 +
 +
  <!-- Wrapper for slides -->
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  <div class="carousel-inner" role="listbox">
 +
    <div class="item active">
 +
      <img src="https://static.igem.org/mediawiki/2015/d/d7/Team-Cairo_Egypt_hme1.jpg" alt="...">
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    </div>
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 +
    <div class="item">
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      <img src="https://static.igem.org/mediawiki/2015/4/41/Team-Cairo_Egypt_hme5.jpg" alt="...">
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    </div>
 +
    <div class="item">
 +
      <img src="https://static.igem.org/mediawiki/2015/e/e4/Team-Cairo_Egypt_hme6.jpg" alt="...">
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    </div>
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  </div>
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</div>
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</div>
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                    </div>
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                    <!-- /.row (nested) -->
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                </div>
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                <!-- /.col-lg-10 -->
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            </div>
 +
            <!-- /.row -->
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        </div>
 +
        <!-- /.container -->
 +
    </section>
  
−
<h4>Tips</h4>
+
    <!-- Map -->
−
<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
+
    <section id="contact" class="map">
−
<ul>
+
       
−
<li>State your accomplishments! Tell people what you have achieved from the start. </li>
+
      <iframe src="https://www.google.com/maps/d/embed?mid=zjcRgsVp8YzE.kjlWSjKWfOgM" width="100%" height="100%" frameborder="0" scrolling="no" marginheight="0" marginwidth="0"></iframe>
−
<li>Be clear about what you are doing and how you plan to do this.</li>
+
    </section>
−
<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
+
−
<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
+
−
<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
+
−
<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2015.igem.org/Calendar_of_Events">iGEM 2015 calendar</a> </li>
+
−
<li>Have lots of fun! </li>
+
−
</ul>  
+
  
 +
    <!-- Footer -->
 +
    <footer>
 +
        <div class="container">
 +
            <div class="row">
 +
                <div class="col-lg-10 col-lg-offset-1 text-center">
 +
                    <h4><strong>IGEM | Egypt</strong>
 +
                    </h4>
 +
                    <br>
 +
                    <ul class="list-inline">
 +
                        <li>
 +
                            <a href="https://www.facebook.com/iGEMEgypt"><i class="fa fa-facebook fa-fw fa-3x"></i></a>
 +
                        </li>
 +
                        <li>
 +
                            <a href="https://www.youtube.com/channel/UC5Wr8uJESsDN37EQ9QY1sAA"><i class="fa fa-youtube fa-fw fa-3x"></i></a>
 +
                        </li>
 +
                        <li>
 +
                            <a href="mailto:igem.egyptian.lab@gmail.com"><i class="fa fa-envelope fa-fw fa-3x"></i></a>
 +
                        </li>
 +
                        <li>
 +
                            <a href="https://www.facebook.com/groups/714799951953916/"><i class="fa fa-globe fa-fw fa-3x"></i></a>
 +
                        </li>
 +
                        <li>
 +
                            <a href="https://trello.com/b/n2gsYld5/admin"><i class="fa fa-trello fa-fw fa-3x"></i></a>
 +
                        </li>
 +
                    </ul>
 +
                    <hr class="small">
 +
                    <p class="text-muted">Copyright &copy; IGEM | Egypt 2015</p>
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<h4>Inspiration</h4>
 
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<p> You can also view other team wikis for inspiration! Here are some examples:</p>
 
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<ul>
 
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<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
 
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<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
 
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<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
 
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<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
 
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<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
 
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<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
 
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</ul>
 
  
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<h4> Uploading pictures and files </h4>
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<p> You can upload your pictures and files to the iGEM 2015 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
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    <script src="https://2015.igem.org/Team:Cairo_Egypt/js/bootstrap?action=raw&amp;ctype=text/javascript" type="text/javascript"></script>
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When you upload, set the "Destination Filename" to <code>Team:YourOfficialTeamName/NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p>
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<a href="https://2015.igem.org/Special:Upload">CLICK HERE TO UPLOAD FILES</a>
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        $('a[href*=#]:not([href=#])').click(function() {
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Latest revision as of 03:52, 19 September 2015

Project ABC

Cairo | Egypt Team


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Brief Description

Breast cancer is the most common malignancy in women and constitutes 18% of all female cancers (Jemal et al., 2002) Although there has been a slight decrease in mortality in breast cancer patients (Schiffman et al., 2002), it is not uncommon for even early-stage breast cancer to metastasize. Therefore, novel therapeutic strategies are constantly being pursued (Bange et al., 2001). It has been reported that some bacterial species preferentially replicate and accumulate within tumors. At critical cell densities, the binding of a regulator protein to the signal leads to the switch on of genes controlled by QS and therefore a coordinated population response Moreover, they possess certain advantageous features such as motility, capacity to simultaneously carry and express multiple therapeutic proteins. Its elimination by antibiotics makes it a promising new strategy in cancer treatment. Azurin is a copper-containing redox protein with low molecular Weight which can efficiently induce cell apoptosis by raising the intracellular levels of p53 and Bax. It has been found that Azurin receptors are hyper expressed on the surfaces of cancer cells relative to their expression on the surfaces of normal cells. We do intend to modify genetic material of bacteria species that localize and induce expression of Azurin in presence of tumor only.

What we have

Team

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Description

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Experiments

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Results

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Parts

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Practices

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Notebook

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Attributions

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Collaborations

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IGEM | Egypt


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