Difference between revisions of "Team:Cairo Egypt"

 
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<link rel="stylesheet" href="https://2015.igem.org/Team:Cairo_Egypt/css/igem_toolbar_style?action=raw&ctype=text/css" type="text/css">
 
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<link rel="stylesheet" href="https://2015.igem.org/Team:Cairo_Egypt/css/custom?action=raw&ctype=text/css" type="text/css">
 
 
<link rel="stylesheet" href="https://2015.igem.org/Team:Cairo_Egypt/css/home_style?action=raw&ctype=text/css" type="text/css">
 
<link rel="stylesheet" href="https://2015.igem.org/Team:Cairo_Egypt/css/home_style?action=raw&ctype=text/css" type="text/css">
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<link rel="stylesheet" href="https://2015.igem.org/Team:Cairo_Egypt/css/custom?action=raw&ctype=text/css" type="text/css">
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<link rel="stylesheet" href="//maxcdn.bootstrapcdn.com/font-awesome/4.3.0/css/font-awesome.min.css">
 
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<link href="http://fonts.googleapis.com/css?family=Source+Sans+Pro:300,400,700,300italic,400italic,700italic" rel="stylesheet" type="text/css">
  
 
<!-- Navigation -->
 
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            <li class="sidebar-brand">
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                 <a href="#top"  onclick = $("#menu-close").click(); >Project ABC</a>
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                 <span class="icon-bar"></span>
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            </li>
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                 <span class="icon-bar"></span>
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            <li>
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                 <a href="#top" onclick = $("#menu-close").click(); >Home</a>
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             </button>
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            </li>
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             <a class="navbar-brand" href="#page-top">Cairo | Egypt</a>
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            <li>
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         </div>
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                 <a href="#about" onclick = $("#menu-close").click(); >About</a>
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            </li>
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            <li>
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                 <a href="#services" onclick = $("#menu-close").click(); >What we have</a>
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             </li>
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             <li>
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                <a href="#contact" onclick = $("#menu-close").click(); >Contact</a>
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    </nav>
  
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            <h1>Project ABC</h1>
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                    <a href="#page-top"></a>
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            <h3>Cairo | Egypt Team</h3>
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                </li>
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            <br>
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                <li class="page-scroll">
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            <a href="#about" class="btn btn-dark btn-lg">Find Out More</a>
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                    <a href="#portfolio">Portfolio</a>
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                </li>
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                <li class="page-scroll">
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                    <a href="#about">About</a>
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                </li>
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                <li class="page-scroll">
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                    <a href="#contact">Contact</a>
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     <!-- About -->
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    <section id="about" class="about">
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                <img class="img-responsive" src="https://static.igem.org/mediawiki/2015/4/49/Profile.png" alt="">
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                <br>
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                <div class="intro-text">
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                    <span class="name">Cairo | Egypt</span>
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                    <br>
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                    <hr class="star-light">
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                    <span class="skills">We are in trying to win</span>
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                     <h2>Portfolio</h2>
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                     <h2>Brief Description</h2>
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                     <hr class="star-primary">
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                     <p class="lead">Breast cancer is the most common malignancy in women and constitutes 18% of all female cancers (Jemal et al., 2002) Although there has been a slight decrease in mortality in breast cancer patients (Schiffman et al., 2002), it is not uncommon for even early-stage breast cancer to metastasize. Therefore, novel therapeutic strategies are constantly being pursued (Bange et al., 2001). It has been reported that some bacterial species preferentially replicate and accumulate within tumors. At critical cell densities, the binding of a regulator protein to the signal leads to the switch on of genes controlled by QS and therefore a coordinated population response Moreover, they possess certain advantageous features such as motility, capacity to simultaneously carry and express multiple therapeutic proteins. Its elimination by antibiotics makes it a promising new strategy in cancer treatment. Azurin is a copper-containing redox protein with low molecular Weight which can efficiently induce cell apoptosis by raising the intracellular levels of p53 and Bax. It has been found that Azurin receptors are hyper expressed on the surfaces of cancer cells relative to their expression on the surfaces of normal cells. We do intend to modify genetic material of bacteria species that localize and induce expression of Azurin in presence of tumor only.</p>
 
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            <!-- /.row -->
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                 <div class="col-sm-4 portfolio-item">
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        <!-- /.container -->
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                                 <i class="fa fa-search-plus fa-3x"></i>
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    <!-- Services -->
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    <!-- The circle icons use Font Awesome's stacked icon classes. For more information, visit http://fontawesome.io/examples/ -->
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    <section id="services" class="services bg-primary">
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        <div class="container">
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             <div class="row text-center">
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                 <div class="col-lg-10 col-lg-offset-1">
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                     <h2>What we have</h2>
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                    <hr class="small">
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                    <div class="row">
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                         <div class="col-md-3 col-sm-6">
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                             <div class="service-item">
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                                <span class="fa-stack fa-4x">
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                                 <i class="fa fa-circle fa-stack-2x"></i>
 +
                                <i class="fa fa-group fa-stack-1x text-primary"></i>
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                            </span>
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                                <h4>
 +
                                    <strong>Team</strong>
 +
                                </h4>
 +
                                <p>Learn more about the team and the instructors.</p>
 +
                                <a class="btn btn-light" href="https://2015.igem.org/Team:Cairo_Egypt/Team">Learn More</a>
 
                             </div>
 
                             </div>
 
                         </div>
 
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                                <span class="fa-stack fa-4x">
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                                <i class="fa fa-circle fa-stack-2x"></i>
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                    <a href="#portfolioModal2" class="portfolio-link" data-toggle="modal">
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                                 <i class="fa fa-file-text-o fa-stack-1x text-primary"></i>
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                                <h4>
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                                 <i class="fa fa-search-plus fa-3x"></i>
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                                    <strong>Description</strong>
 +
                                </h4>
 +
                                <p>Learn more about project and results.</p>
 +
                                <a href="https://2015.igem.org/Team:Cairo_Egypt/Description" class="btn btn-light">Learn More</a>
 
                             </div>
 
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                                <span class="fa-stack fa-4x">
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                <div class="col-sm-4 portfolio-item">
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                                <i class="fa fa-circle fa-stack-2x"></i>
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                    <a href="#portfolioModal3" class="portfolio-link" data-toggle="modal">
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                                 <i class="fa fa-flask fa-stack-1x text-primary"></i>
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                        <div class="caption">
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                            </span>
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                            <div class="caption-content">
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                                <h4>
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                                 <i class="fa fa-search-plus fa-3x"></i>
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                                    <strong>Experiments</strong>
 +
                                </h4>
 +
                                <p>Learn more about project and experiments and protocols.</p>
 +
                                <a href="https://2015.igem.org/Team:Cairo_Egypt/Experiments" class="btn btn-light">Learn More</a>
 
                             </div>
 
                             </div>
 
                         </div>
 
                         </div>
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                         <img src="https://static.igem.org/mediawiki/2015/7/73/Safe.png" class="img-responsive" alt="">
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                            <div class="service-item">
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                                <span class="fa-stack fa-4x">
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                <div class="col-sm-4 portfolio-item">
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                                <i class="fa fa-circle fa-stack-2x"></i>
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                    <a href="#portfolioModal4" class="portfolio-link" data-toggle="modal">
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                                 <i class="fa fa-bar-chart fa-stack-1x text-primary"></i>
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                        <div class="caption">
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                            </span>
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                            <div class="caption-content">
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                                <h4>
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                                 <i class="fa fa-search-plus fa-3x"></i>
+
                                    <strong>Results</strong>
 +
                                </h4>
 +
                                <p>Learn more about project and results.</p>
 +
                                <a href="https://2015.igem.org/Team:Cairo_Egypt/Results" class="btn btn-light">Learn More</a>
 
                             </div>
 
                             </div>
 
                         </div>
 
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                                <span class="fa-stack fa-4x">
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                <div class="col-sm-4 portfolio-item">
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                                <i class="fa fa-circle fa-stack-2x"></i>
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                    <a href="#portfolioModal5" class="portfolio-link" data-toggle="modal">
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                                 <i class="fa fa-gears fa-stack-1x text-primary"></i>
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                        <div class="caption">
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                            </span>
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                            <div class="caption-content">
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                                <h4>
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                                 <i class="fa fa-search-plus fa-3x"></i>
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                                    <strong>Parts</strong>
 +
                                </h4>
 +
                                <p>Know more about parts here used in the project.</p>
 +
                                <a href="https://2015.igem.org/Team:Cairo_Egypt/Parts" class="btn btn-light">Learn More</a>
 
                             </div>
 
                             </div>
 
                         </div>
 
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                    </a>
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                            <div class="service-item">
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                                <span class="fa-stack fa-4x">
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                <div class="col-sm-4 portfolio-item">
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                                <i class="fa fa-circle fa-stack-2x"></i>
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                    <a href="#portfolioModal6" class="portfolio-link" data-toggle="modal">
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                                 <i class="fa fa-futbol-o fa-stack-1x text-primary"></i>
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                        <div class="caption">
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                            </span>
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                            <div class="caption-content">
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                                <h4>
−
                                 <i class="fa fa-search-plus fa-3x"></i>
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                                    <strong>Practices</strong>
 +
                                </h4>
 +
                                <p>Learn more about human practice here.</p>
 +
                                <a href="https://2015.igem.org/Team:Cairo_Egypt/Practices" class="btn btn-light">Learn More</a>
 
                             </div>
 
                             </div>
 
                         </div>
 
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                         <img src="https://static.igem.org/mediawiki/2015/7/73/Safe.png" class="img-responsive" alt="">
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                         <div class="col-md-3 col-sm-6">
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                     </a>
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                            <div class="service-item">
 +
                                <span class="fa-stack fa-4x">
 +
                                <i class="fa fa-circle fa-stack-2x"></i>
 +
                                <i class="fa fa-book fa-stack-1x text-primary"></i>
 +
                            </span>
 +
                                <h4>
 +
                                    <strong>Notebook</strong>
 +
                                </h4>
 +
                                <p>Know more about agenda and what was done.</p>
 +
                                <a href="https://2015.igem.org/Team:Cairo_Egypt/Notebook" class="btn btn-light">Learn More</a>
 +
                            </div>
 +
                        </div>
 +
                        <div class="col-md-3 col-sm-6">
 +
                            <div class="service-item">
 +
                                <span class="fa-stack fa-4x">
 +
                                <i class="fa fa-circle fa-stack-2x"></i>
 +
                                <i class="fa fa-smile-o fa-stack-1x text-primary"></i>
 +
                            </span>
 +
                                <h4>
 +
                                    <strong>Attributions</strong>
 +
                                </h4>
 +
                                <p>Know who did what in this project from the beginning</p>
 +
                                <a href="https://2015.igem.org/Team:Cairo_Egypt/Attributions" class="btn btn-light">Learn More</a>
 +
                            </div>
 +
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                    <p>Breast cancer is the most common malignancy in women and constitutes 18% of all female cancers (Jemal et al., 2002) Although there has been a slight decrease in mortality in breast cancer patients (Schiffman et al., 2002), it is not uncommon for even early-stage breast cancer to metastasize. Therefore, novel therapeutic strategies are constantly being pursued (Bange et al., 2001). It has been reported that some bacterial species preferentially replicate and accumulate within tumors. At critical cell densities, the binding of a regulator protein to the signal leads to the switch on of genes controlled by QS and therefore a coordinated population response Moreover, they possess certain advantageous features such as motility, capacity to simultaneously carry and express multiple therapeutic proteins. Its elimination by antibiotics makes it a promising new strategy in cancer treatment. Azurin is a copper-containing redox protein with low molecular Weight which can efficiently induce cell apoptosis by raising the intracellular levels of p53 and Bax. It has been found that Azurin receptors are hyperexpressed on the surfaces of cancer cells relative to their expression on the surfaces of normal cells. We do intend to modify genetic material of bacteria specie that localize and induce expression of Azurin in presence of tumor only.
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Latest revision as of 03:52, 19 September 2015

Project ABC

Cairo | Egypt Team


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Brief Description

Breast cancer is the most common malignancy in women and constitutes 18% of all female cancers (Jemal et al., 2002) Although there has been a slight decrease in mortality in breast cancer patients (Schiffman et al., 2002), it is not uncommon for even early-stage breast cancer to metastasize. Therefore, novel therapeutic strategies are constantly being pursued (Bange et al., 2001). It has been reported that some bacterial species preferentially replicate and accumulate within tumors. At critical cell densities, the binding of a regulator protein to the signal leads to the switch on of genes controlled by QS and therefore a coordinated population response Moreover, they possess certain advantageous features such as motility, capacity to simultaneously carry and express multiple therapeutic proteins. Its elimination by antibiotics makes it a promising new strategy in cancer treatment. Azurin is a copper-containing redox protein with low molecular Weight which can efficiently induce cell apoptosis by raising the intracellular levels of p53 and Bax. It has been found that Azurin receptors are hyper expressed on the surfaces of cancer cells relative to their expression on the surfaces of normal cells. We do intend to modify genetic material of bacteria species that localize and induce expression of Azurin in presence of tumor only.

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Team

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Description

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IGEM | Egypt


Copyright © IGEM | Egypt 2015