Difference between revisions of "Team:Stockholm/Description"

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<h2> Project Description </h2>
 
<h2> Project Description </h2>
  
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<p>Tell us about your project, describe what moves you and why this is something important for your team.</p>
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<p>Synthetic biology offers many potential cost-effective healthcare technologies. One of those could be new ways to diagnose and treat disease at an early stage. Current techniques for biomarker detection (e.g. ELISA, RIA) are time consuming, expensive and require specialised equipment. <br />
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<h5>What should this page contain?</h5>
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We intend to design a microbiological system for the detection of low quantities of biomarkers. This assay aims to be easier and more cost efficient than existing techniques and possible to perform in modestly equipped settings. Initially, we will focus on the expression of a receptor for the desired biomarker. Depending on the nature of the biomarker, the receptor will be either be native or designed. <br />
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<li> A clear and concise description of your project.</li>
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<li>A detailed explanation of why your team chose to work on this particular project.</li>
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<li>References and sources to document your research.</li>
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Upon biomarker detection, signal amplification will be triggered by our receptor system to activate a read out/detection system (e.g. Luciferase, GFP) inside the microorganism to artificially amplify the extracellular signal. In the next stage, the team will go on to design a read-out system to measure the concentration of biomarkers in body samples. Finally we want to investigate if we can make this system transferable to other biomarkers, changing only the receptor part of the system. <br />
  
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The system would be cheap, fast and possible to distribute without advanced equipment. Our motivation is to improve patient prognosis and quality of life and to improve efficiency and reduce costs within the healthcare system. </p>
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<h4>Advice on writing your Project Description</h4>
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We encourage you to put up a lot of information and content on your wiki, but we also encourage you to include summaries as much as possible. If you think of the sections in your project description as the sections in a publication, you should try to be consist, accurate and unambiguous in your achievements.
 
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Judges like to read your wiki and know exactly what you have achieved. This is how you should think about these sections; from the point of view of the judge evaluating you at the end of the year.
 
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<h4>References</h4>
 
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<p>iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you though about your project and what works inspired you.</p>
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<p>I'm a little placeholder short and stout... <p>
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<h4>Inspiration</h4>
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<p>See how other teams have described and presented their projects: </p>
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<li><a href="https://2014.igem.org/Team:Imperial/Project"> Imperial</a></li>
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<li><a href="https://2014.igem.org/Team:UC_Davis/Project_Overview"> UC Davis</a></li>
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<li><a href="https://2014.igem.org/Team:SYSU-Software/Overview">SYSU Software</a></li>
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Revision as of 18:45, 29 May 2015

Temporary Banner Stockholm

Project Description

Synthetic biology offers many potential cost-effective healthcare technologies. One of those could be new ways to diagnose and treat disease at an early stage. Current techniques for biomarker detection (e.g. ELISA, RIA) are time consuming, expensive and require specialised equipment.
We intend to design a microbiological system for the detection of low quantities of biomarkers. This assay aims to be easier and more cost efficient than existing techniques and possible to perform in modestly equipped settings. Initially, we will focus on the expression of a receptor for the desired biomarker. Depending on the nature of the biomarker, the receptor will be either be native or designed.
Upon biomarker detection, signal amplification will be triggered by our receptor system to activate a read out/detection system (e.g. Luciferase, GFP) inside the microorganism to artificially amplify the extracellular signal. In the next stage, the team will go on to design a read-out system to measure the concentration of biomarkers in body samples. Finally we want to investigate if we can make this system transferable to other biomarkers, changing only the receptor part of the system.
The system would be cheap, fast and possible to distribute without advanced equipment. Our motivation is to improve patient prognosis and quality of life and to improve efficiency and reduce costs within the healthcare system.


References

I'm a little placeholder short and stout...