Team:ETH Zurich/Modeling/AHL Module

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• Modeling
  • Overview
  • Lactate Module
  • AHL Module
  • Compartment Model
  • Reaction-Diffusion
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• About Us
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• Project
  • Project Description
  • Design
  • Applications
  • Achievements
  • Collaborations
  • Glossary
  • References
• Modeling
  • Overview
  • Lactate Module
  • AHL Module
  • Compartment Model
  • Reaction-Diffusion
  • Experiments Meet Modeling
  • Parameters
• Lab
  • Overview
  • Results
  • Chip Design
  • Experiments
  • Interlab Study
  • Safety
  • Notebook
  • Materials
• Human
  Practices
  • Overview
  • Medicine
  • Education
  • Awareness
  • Ethics
  • Business
  • Patents
• Parts
  • Overview
  • Basic
  • Composite
  • Part Collection
  • Characterization
• About Us
  • Team
  • Attributions
  • iGEM Team Roster

"What I cannot create I do not understand."
- Richard Feynmann

AHL Module

Introduction

Chemical species

Name	Description
AHL	Signaling protein, Acyl homoserine lactone (30C6-HSL)
LuxR	Regulator protein, that can bind to AHL to form a complex
LuxRAHL	Complex of LuxR and AHL, activates transcription of LuxI
LuxI	Autoinducer synthase
Aiia	AHL-lactonase, N-Acyl Homoserine Lactone Lactonase

Reactions

Equations

The equations are based on mass action kinetics and basic rate laws such as Hill equation.

Assumptions

Simplified equations