Team:Harvard BioDesign
NAME OF PROJECT
Welcome to the Harvard BioDesign 2015 wiki!
The "official" place where flocculation happens and llamas are appreciated.
About Our Project
Our team is engineering E. coli to bind to colon cancer cells through the use of their type I pili, which are hair-like appendages
that have an adhesive domain. Naturally, the strains in E. coli that produce pili bind to alpha-D-mannose, which can cause urinary track infections.
However, our team is altering a non-harmful strain to produce pili using a modified Fim gene in order to localize the bacteria as a tool. For treatment of cancer,
once the bacteria are localized on the cells, the next step is to make the
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About Me
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Contact
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