Team:EPF Lausanne/Test
Bio LOGIC
Logic Orthogonal gRNA Implemented Circuits
Engineering transcriptional logic gates to program cellular behavior remains an important challenge for synthetic biology. Currently, genetic circuits reproducing digital logic are limited in scalability and robustness by output discrepancies and crosstalk between transcriptional pathways. We propose to address these issues using RNA-guided dCas9 fused to a transcription activation domain as a programmable transcription factor.
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Project
Background
Discover the ideas behind our project, from boolean logic to the the complete explanation of a biologic logic gate.
Description
Understand our project in the smallest details and explore the world of CRISPR-dCas9 with us.
Applications
Need a biosensor? Want a bacteria that could depollute a lake? Here are a few examples of how you could apply our technology for your own designs.
Modelling
Having a robust system is the key to devise a new concept and testing it in silico before ordering the expensive parts.
Interlab study
Having a robust system is the key to devise a new concept and testing it in silico before ordering the expensive parts.
Achievements
In Vivo
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In Silico
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Judging
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Parts
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Policy & Practices
Ethics
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Safety
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Human Practices
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Notebook
E. coli
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Yeast
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Protocols
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Team
Meet us
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Timeline
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Aknowledgements
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