Difference between revisions of "Team:Marburg"

 
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+
 
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</style>
 
</style>
  
−
<nav class="fixed-nav-bar">
 
−
<div id="menu" class="menu">
 
−
<div class="menu-items">
 
−
<ul>
 
−
<li><a href="https://2015.igem.org/Team:Marburg">Home</a></li>
 
−
<li><a href="https://2015.igem.org/Team:Marburg/Parts">Parts</a></li>   
 
−
<li><a href="https://2015.igem.org/Team:Marburg/Experiments">Project</a></li> 
 
−
<li><a href="https://2015.igem.org/Team:Marburg/Collaborations">Collaborations</a></li>
 
−
<li><a href="https://2015.igem.org/Team:Marburg/Notebook">Notebook</a></li>
 
−
<li><a href="https://2015.igem.org/Team:Marburg/Team">Team</li>
 
−
<li><a href="https://2015.igem.org/Team:Marburg/HumanPractice">Human Practice</a></li>
 
−
<li><a href="https://2015.igem.org/Team:Marburg/Interlabstudy">InterLab Study</a></li>
 
−
        </ul>
 
−
        </div>
 
−
        </div>
 
−
</nav>
 
  
−
<h1 style="color: #00cdcd" "font-size:200%"><center>This page is in progress!</center></h1><br>
+
<!--JS for Mailus-->
−
<h2 style="font-size:200%">Our Project</h2>
+
<script>
 +
$(document).ready(function() {
 +
$('#maillink').hover(function() {
 +
                    console.log("AAA");
 +
            var link = 'mailto:igemteam!#%synmikro.uni-marburg.de';
 +
      $(this).attr('href',link.replace("!#%","@"));
 +
                });
 +
});
 +
</script>
 +
 
 +
 
 +
<!--HTML-MENU-->
 +
 
 +
<body style="height:100%;min-width:100%;margin:0px; padding:0px;">
 +
<div style="position:fixed;width:100%; min-width:100%; height:100%;min-height:100%; background-image: url('https://static.igem.org/mediawiki/2015/6/6f/MR_pic_bg6.jpg');background-repeat: no-repeat;
 +
    background-attachment: fixed;-webkit-background-size: cover;
 +
  -moz-background-size: cover;
 +
  -o-background-size: cover;
 +
  background-size: cover;
 +
margin:0px; padding:0px;"></div>
 +
<div style="position:absolute;margin-left:-680px;left:50%;width:1360px;min-width:1360px;min-height:100%;background-color:white;padding-bottom:10px;">
 +
<div style="position:fixed;width:1360px;min-width:1360;height:70px;z-index:20;margin-top:0px;">
 +
<div style="display:table;min-width:1360px;height:100%;">
 +
<div style="display:table-row;">
 +
<div style="display:table-cell;width:188px;background:white;">
 +
<a href="https://2015.igem.org/Team:Marburg" style="text-align:center;">
 +
<img src="https://static.igem.org/mediawiki/2015/1/14/MR_pic_Home.png" style="position:relative;height:66px;padding-bottom:11px;padding-left:8px;padding-right:8px;">
 +
</a>
 +
</div>
 +
<div style="display:table-cell;background:#E0E0E0;padding-left:20px;">
 +
<nav id="nav">
 +
<ul id="navigation" style="margin-top:9px;">
 +
<li><a href="https://2015.igem.org/Team:Marburg/Projects" class="first"><img src="https://static.igem.org/mediawiki/2015/5/56/MR_pic_Projects.png" style="height:60px;text-align:center;"></a>
 +
<ul>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Description">Overview</a></li>
 +
                                                                <li><a href="https://2015.igem.org/Team:Marburg/Background">Fact Sheets</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Minicells">NUTRInity - Provide</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Curli">NUTRInity - Pick up</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/CDI">NUTRInity - Cut off</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Design">Future Application</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/InterLab">InterLab Study</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Measurement">Measurement Study</a></li>
 +
</ul>
 +
</li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Practices" class="first"><img src="https://static.igem.org/mediawiki/2015/3/3a/MR_pic_HP.png" style="height:60px;"></a>
 +
<ul>
 +
<li><a href="https://2015.igem.org/Team:Marburg/iGeneration">iGeneration</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Hessentag">Hessentag</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Killswitch">KillSwitch Statistics</a></li>
 +
</ul>
 +
</li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Achievements" class="first"><img src="https://static.igem.org/mediawiki/2015/b/ba/MR_pic_Achievements.png" style="height:60px;"></a>
 +
<ul>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Parts">Parts</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Results">Results</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Medal Fulfillment">Medal Fulfillment</a></li>
 +
</ul>
 +
</li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Collaborations" class="first"><img src="https://static.igem.org/mediawiki/2015/7/71/MR_pic_Collaborations.png" style="height:60px;"></a>
 +
<ul>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Meetup">MeetUp</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Gameofcells">Game of Cells</a></li>
 +
</ul>
 +
</li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Notebook" class="first"><img src="https://static.igem.org/mediawiki/2015/5/53/MR_pic_Notebook.png" style="height:60px;"></a>
 +
<ul>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Labbook">Lab Book</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Protocols">Protocols</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Bibliography">Bibliography</a></li>
 +
</ul>
 +
</li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Team" class="first"><img src="https://static.igem.org/mediawiki/2015/1/1d/MR_pic_Team.png" style="height:60px;"></a>
 +
<ul>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Members">Members</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Acknowledgement">Acknowledgement</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Attributions">Attributions</a></li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Gallery">Gallery</a></li>
 +
</ul>
 +
</li>
 +
<li><a href="https://2015.igem.org/Team:Marburg/Safety" class="first"><img src="https://static.igem.org/mediawiki/2015/6/6a/MR_pic_Safety.png" style="height:60px;"></a>
 +
<ul>
 +
                        <li><a href="https://2015.igem.org/Team:Marburg/Killswitch">KillSwitch Statistics</a></li>
 +
</ul>
 +
</li>
 +
 
 +
</ul>
 +
</nav>
 +
</div>
 +
<div id="socialmedia" style="display:table-cell;background:#E0E0E0;text-align:right;padding-right:5px;vertical-align:middle;">
 +
<span id="smbuttons">
 +
<a href="https://www.facebook.com/igemmarburg" class="second" style="padding:5px;"><img src="https://static.igem.org/mediawiki/2015/7/71/MR_pic_Facebook.png" style="width:30px;"></a>
 +
<a href="https://twitter.com/igem_marburg" class="second" style="padding:5px;"><img src="https://static.igem.org/mediawiki/2015/7/75/MR_pic_Twitter.png" style="width:30px;"></a>
 +
<a id="maillink" href="#" style="padding:5px;" class="second"><img src="https://static.igem.org/mediawiki/2015/a/a0/MR_pic_Mailus.png" style="width:30px;" alt="submit"></a>
 +
<a href="https://2015.igem.org/Main_Page" class="second" style="padding:5px;"><img src="https://static.igem.org/mediawiki/2015/9/9b/MR_pic_Igem.png" style="width:30px;"></a>
 +
</span>
 +
</div><!-- cell -->
 +
</div>
 +
</div>
 +
</div><!-- row -->
 +
 +
<div style="position:fixed;min-height:100%;height:100%;width:195px;background:#E0E0E0;top:115px;z-index:20;vertical-align:middle;">
 +
<span style="margin:0px; padding:0px;display:inline-block;height:100%;vertical-align:middle;">
 +
</span>
 +
<img src="https://static.igem.org/mediawiki/2015/1/1c/MR_pic_Sidebanner_Home.png" style="width:184px;vertical-align:middle;">
 +
</div>
 +
<div style="position:fixed;margin-left:640px;height:100%;min-height:100%;min-width:40px; width:40px; top:115px;background:#E0E0E0; left:50%;z-index:2;"></div>
 +
 
 +
<div>
 +
<div style="position:relative;text-align:justify;z-index:1;background:white;font-size:13pt;line-height:150%;min-width:100%;max-width:100%;padding-top:132px; padding-left:235px; padding-right:80px;padding-bottom:70px;box-sizing: border-box;">
 +
<style>
 +
.subpanel1 { /* Overview */
 +
    float:left;
 +
    width:500px;
 +
    height:550px;
 +
    margin-top:0;
 +
    margin-right:15px;
 +
    margin-bottom:0px;
 +
    border-color:#FF8F45;
 +
    border-style:solid;
 +
    border-width:2px;
 +
    border-radius:7px;
 +
    background:#FFF0DE;
 +
   
 +
}
 +
 
 +
.subpanel2 { /* Projects */
 +
    float:right;
 +
    width:230px;
 +
    text-align:left;
 +
    margin-top:0;
 +
    margin-right:5px;
 +
    border-radius:7px;
 +
    overflow:hidden;
 +
}
 +
 
 +
.subpanel2:hover {
 +
    opacity:0.6;
 +
    filter: alpha(opacity=60);
 +
}
 +
 
 +
.subpanel3 { /* Results */
 +
    height:40px;
 +
    font-size:24px;
 +
    text-align:center;
 +
    line-height:40px;
 +
    background:#FF8F45;
 +
    color:white;
 +
    border-color:#FF8F45;
 +
    border-style:solid;
 +
    border-width:2px;
 +
    border-radius:7px;
 +
    margin-top:30px;
 +
    bottom:5px;
 +
    padding-bottom:5px; 
 +
}
 +
 
 +
.subpanel3:hover {
 +
    opacity:0.6;
 +
    filter: alpha(opacity=60);
 +
}
 +
 
 +
.subpanel4 {
 +
    width: 232px;
 +
    border-radius:10px;
 +
    margin:5px;
 +
 
 +
}
 +
 
 +
.subpanel4:hover {
 +
    opacity:0.6;
 +
    filter: alpha(opacity=60);
 +
}
 +
 
 +
.cont { /* Overview content */
 +
    text-align:justify;
 +
    height:auto;
 +
    margin-left:5%;
 +
    margin-right:5%;
 +
    margin-top:5%;
 +
    max-width:90%;
 +
    background:transparent;
 +
}
 +
.cont p {
 +
    line-height:120%;
 +
}
 +
 
 +
.cont1 { /* Overview content */
 +
    text-align:justify;
 +
    height:auto;
 +
    margin-left:5%;
 +
    margin-right:5%;
 +
    margin-top:5%;
 +
    max-width:90%;
 +
    background:transparent;
 +
}
 +
.cont1 p {
 +
    line-height:150%;
 +
}
 +
 
 +
.spdesc { /* Overview content */
 +
    display:none;
 +
    height:100px;
 +
    color:black;
 +
    border-radius:7px;
 +
    background-color:#FFD698;
 +
    padding:1px;
 +
    margin-top:10px;
 +
}
 +
 
 +
.banner{
 +
    width:980px;
 +
    border-radius:20px;
 +
    margin-bottom:20px;
 +
}
 +
 
 +
.arrow {
 +
    padding:5px;
 +
    text-align:right;
 +
}
 +
 
 +
</style>
 +
 
 +
<div style="margin-bottom:30px;margin-right:1%;margin-left:20px;">
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<img src="https://static.igem.org/mediawiki/2015/1/11/MR_pic_Banner.png" class="banner"/>
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<div class="subpanel1">
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<div style="position:relative;bottom:0px">
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<div class="cont"><p style="font-size:26px;line-height:30px;">MAKE THE GUT A BETTER WORLD!</p></div>
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<div class="cont1">
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<p style="font-size:18px;">
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To tackle malnutrition and overconsumption of food represent one of the major challenges of humankind. The iGEM Team Marburg addresses these issues in a holistic approach by developing modular tools. Engineered, cell-based particles produce dietary supplements to alleviate malnutrition. A cell-free protein matrix with a functionalized surface targets specific nutrients to lower their concentration in the human gut. Furthermore, we engineer a contact-dependent delivery system that modifies the human gut microbial community. Taken together, we provide innovative solutions for improving and balancing nutrition at the interface of the human microbiome and gut.
 +
</p>
 +
<div id="psdesc" class="spdesc">
 +
<div class="cont" style="line-height:120%;">
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<p style="font-size:18px;line-height:120%;">We established minicells as a shuttle and production system as well as designed a modular device that makes bacteria minicell producers.</p>
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</div>
 +
</div>
 +
<div id="dsdesc" class="spdesc">
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<div class="cont" style="line-height:120%;">
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<p style="font-size:18px;line-height:120%;">We built a potentially cell free biofilm matrix that can be functionalized to serve customized purposes.</p>
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</div>  
 +
</div>
 +
<div id="thdesc" class="spdesc">
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<div class="cont" style="line-height:120%;">
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<p style="font-size:18px;line-height:120%;">We characterized promotors in different hosts with various methods to get the best-studied BioBrick.</p>
 +
</div>
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</div>
 +
<div id="tcdesc" class="spdesc">
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<div class="cont" style="line-height:120%;">
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<p style="font-size:18px;line-height:120%;">We built a system to establish a niche to modify the human gut microbiome by inhibiting growth of proteobacteria.</p>
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</div>
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</div>
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</div>
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</div>
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</div>
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<div>
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<a href="https://2015.igem.org/Team:Marburg/Minicells" title="Provide">
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<div id="pspanel" class="subpanel2"  onmouseover="chgtrans(this)">
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<img src="https://static.igem.org/mediawiki/2015/f/f2/MR_pic_FactPro.png" width="200px"/>
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</div>
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</a>
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<a href="https://2015.igem.org/Team:Marburg/Curli" title="Pick-up">
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<div id="dspanel" class="subpanel2">
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<img src="https://static.igem.org/mediawiki/2015/3/3a/MR_pic_FactPick.png" width="200px"/>
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</div>
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</a>
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<a href="https://2015.igem.org/Team:Marburg/CDI" title="Cut-off">
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<div id="tcpanel" class="subpanel2">
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<img src="https://static.igem.org/mediawiki/2015/2/24/MR_pic_FactCut.png" width="200px"/>
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</div>
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</a>
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<a href="https://2015.igem.org/Team:Marburg/Measurement" title="Measurement">
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<div id="thpanel" class="subpanel2">     
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<img src="https://static.igem.org/mediawiki/2015/e/e4/MR_pic_ButM.png" width="200px"/>
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</div>
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</a>
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</div>
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<p style="margin-top:10px;">
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<table>
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<td>
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<a href="https://2015.igem.org/Team:Marburg/Results" title="Results" style="margin-top:50px;">
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<div class="subpanel3" style="width:205px;">
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<p style="padding-bottom:5px;"><i>Go to Results!</i></p>
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</div>
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</a>
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</td>
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<td>
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<a href="https://2015.igem.org/Team:Marburg/Medal Fulfillment" title="Medal" style="margin-top:50px;">
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<div class="subpanel3" style="width:305px;">
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<p style="padding-bottom:5px;"><i>Go to Medal Fulfillment!</i></p>
 +
                                                   
 +
</div>
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</a>
 +
</td>
 +
<td>
 +
<a href="https://2015.igem.org/Team:Marburg/Parts" title="Parts" style="margin-top:50px;">
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<div class="subpanel3" style="width:225px;">
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<p style="padding-bottom:5px;"><i>Go to Parts!</i></p>
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</div>
 +
</a>
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</td>
 +
                                <td>
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<a href="https://2015.igem.org/Team:Marburg/Safety" title="Safety" style="margin-top:50px;">
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<div class="subpanel3" style="width:215px;">
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<p style="padding-bottom:5px;"><i>Go to Safety!</i></p>
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</div>
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</a>
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</td>
 +
</table>
 +
</p>
 +
</div>
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<div style="margin-bottom:30px;margin-left:20px;">
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<a href="https://2015.igem.org/Team:Marburg/InterLab" title="ILS"><img src="https://static.igem.org/mediawiki/2015/a/a4/MR_pic_FactInter.png" class="subpanel4"/></a>
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<a href="https://2015.igem.org/Team:Marburg/Collaborations" title="Col"><img src="https://static.igem.org/mediawiki/2015/0/06/MR_pic_BUTCol.png" class="subpanel4"/></a>
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<a href="https://2015.igem.org/Team:Marburg/Design" title="FA"><img src="https://static.igem.org/mediawiki/2015/4/49/MR_pic_BUTfut.png" class="subpanel4"/></a>
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<a href="https://2015.igem.org/Team:Marburg/Practices" title="HP"><img src="https://static.igem.org/mediawiki/2015/4/47/MR_pic_BUThp.png" class="subpanel4"/></a>
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</div>
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$(document).ready(function(){$('div #pspanel').mouseover(function(){div = $('#psdesc');div.fadeIn(1);}).mouseout(function(){div.fadeOut(1);});});
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$(document).ready(function(){$('div #thpanel').mouseover(function(){div = $('#thdesc');div.fadeIn(1);}).mouseout(function(){div.fadeOut(1);});});
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$(document).ready(function(){$('div #tcpanel').mouseover(function(){div = $('#tcdesc');div.fadeIn(1);}).mouseout(function(){div.fadeOut(1);});});
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<div style="position:absolute;text-align:center;z-index:2;background:#e0e0e0;line-height:150%;bottom:0px;padding-top:3px;margin-bottom:0px; padding-left:235px; padding-right:80px;min-height:60px;min-width:100%;max-width:100%;box-sizing:border-box;clear:both;"><!---->
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<p class=ex>This year the iGEM Team Marburg decided to design, build and test various synthetic biological tools. These systems can be used in the future for different applications, from medical set ups to environmental improvements. In order to achieve a holistic approach, we are working in different subgroups that have different objectives, methods and applications. <br>
+
<div>
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The first subgroup is looking into the possibility of generating non-propagating cell factories that are producing only a beneficial compound. Therefore we are using different systems that encode the genetic information and we are building the cell factories.<br>
+
<span style="margin-right:60px;">
−
The second subgroup is currently working on a system to link our organism into a matrix that can enhance biochemical reactions. The idea is to use this as platform technology to link the organic and inorganic chemistry.<br>
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<img src="https://static.igem.org/mediawiki/2015/1/1d/MR_pic_syn.png" style="height:40px;padding:10px;"/>
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Our third and last subgroup focuses on a delivery system for effector proteins in our model organism. Upon association of the donor strain, the system is activated to expose inhibitors or activators on its surface. These proteins are being absorbed by the recipient cell and generate an event there. <br>
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</span>
−
We are also working on the interlab study within the iGEM competition.
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<span>
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</p><br>
+
<img src="https://static.igem.org/mediawiki/2015/5/58/MR_pic_mpii.png" style="height:40px;padding:10px;"/>
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</span>
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<span style="margin-left:60px;">
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<img src="https://static.igem.org/mediawiki/2015/f/f0/MR_pic_unii.png" style="height:40px;padding:10px;"/>
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</span>
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</div>
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    <span style="font-size:8pt; color:white;"> iGEM Marburg - ZSM Karl-von-Frisch-Straße 16, D - 35043 Marburg</span>
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Latest revision as of 19:24, 18 September 2015

MAKE THE GUT A BETTER WORLD!

To tackle malnutrition and overconsumption of food represent one of the major challenges of humankind. The iGEM Team Marburg addresses these issues in a holistic approach by developing modular tools. Engineered, cell-based particles produce dietary supplements to alleviate malnutrition. A cell-free protein matrix with a functionalized surface targets specific nutrients to lower their concentration in the human gut. Furthermore, we engineer a contact-dependent delivery system that modifies the human gut microbial community. Taken together, we provide innovative solutions for improving and balancing nutrition at the interface of the human microbiome and gut.

We established minicells as a shuttle and production system as well as designed a modular device that makes bacteria minicell producers.

We built a potentially cell free biofilm matrix that can be functionalized to serve customized purposes.

We characterized promotors in different hosts with various methods to get the best-studied BioBrick.

We built a system to establish a niche to modify the human gut microbiome by inhibiting growth of proteobacteria.

Go to Results!

Go to Medal Fulfillment!

Go to Parts!

Go to Safety!

iGEM Marburg - ZSM Karl-von-Frisch-Straße 16, D - 35043 Marburg