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| − | <p> Peking iGEM 2015 Team is trying to develop a new detection method based on the nucleic acid of pathogenic microorganism, with the aim of applying it to the diagnosis of pulmonary tuberculosis. It is worth considering for all the researchers of life sciences that how to put the achivements of the basic study into clinical practice. Human practice of Peking this year pays much attention to the identification of the clinical requirements, discussions on the feasibility of our project, and spread of knoweldge about tuberculosis and synthetic biology. By ultilizing the basic ideas of translational medicine, our team has set up a bridge between fundamental research and clinical practices. </p> | + | <p> This year Peking iGEM Team is trying to develop a brand new method for the detection of pathogenic microorganism. Particularly, we expect this method to be applied to the diagnosis of pulmonary tuberculosis as a proof of principle. To see whether our lab achievements can be really helpful to the clinical practice or not, in our human practice we paid the most attention to the clinical requirements for TB detection and the potential issues in economic and ethic perspectives. Additionally, education for both children and adults about the tuberculosis and synthetic biology was another important part. Overall, by the basic ideas of translational medicine, we have successfully set up a bridge between our technological advance and the clinical practices. </p> |
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| − | <dt style="font-weight:400px"><a href="" style="color:#00afd1">Investigation of the current epidemic situation of TB</a></dt> | + | <dt style="font-weight:400px"><a href="" style="color:#00afd1">Investigations on the current epidemic situation of TB</a></dt> |
| − | <dd style="margin-bottom:15px">We’ve interviewed clinicians both in research institute and basic-level hospitals, and researchers of Beijing Research Institute for TB Control. We’ve learned about the epidemic status of TB in China, front diagnostic techniques and their clinical applications. Besides, we’ve visited the central laboratory of Beijing Research Institute for TB Control, and discussed with their researchers on our project, acquiring valuable improvement suggestions.</dd> | + | <dd style="margin-bottom:15px">We first interviewed several representative clinicians from famous research institutes and primary hospitals, as well as the researchers of Beijing Research Institute for TB Control. Through the interviews, we understand the epidemic situation of TB nowadays (especially in China), the most widely used diagnostic techniques, and their clinical applications. We then visited the central laboratory of Beijing Research Institute for TB Control (BRITC) and discussed our proposal with the clinical researchers to obtain valuable suggestions.</dd> |
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| | <dt style="font-weight:400px"><a href="" style="color:#00afd1">Questionnaire survey</a></dt> | | <dt style="font-weight:400px"><a href="" style="color:#00afd1">Questionnaire survey</a></dt> |
| − | <dd style="margin-bottom:15px">We’ve investigated common people about their awareness of tuberculosis and synthetic biology. Analysis of the results reminds us and the government of the urgency to propagandize knowledge of tuberculosis and synthetic biology. Low awareness rate of TB is the cause of high TB burden in China, and a lack of public understanding of synthetic biology will also be an obstacle for us to promote applications of this new subdiscipline in clinical medicine.</dd> | + | <dd style="margin-bottom:15px">We learnt that the low awareness of TB is one of the main causes of high TB burden in China. On the other hand, a lack of public understanding of synthetic biology will be an obstacle for us to promote its application to clinical practices. Therefore, we investigated common people about their awareness of TB and synthetic biology.</dd> |
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| − | <dt style="font-weight:400px"><a href="" style="color:#00afd1">Team as a platform of we-media, new media and scientific popularization</a></dt> | + | <dt style="font-weight:400px"><a href="" style="color:#00afd1">Knowledge popularization of TB and synthetic biology</a></dt> |
| − | <dd style="margin-bottom:15px">This year our team does a lot of work to propagandize knowledge of TB and synthetic biology to both adults and school students, along with the construction of a network platform with more than ** followers. We’ve adopted various means of popularization such as handing out propagandistic handbooks, giving lectures, showing them around iGEM lab, and giving messages to our Wechat followers.</dd> | + | <dd style="margin-bottom:15px">Questionnaire survey showed that most people don’t know much about either TB or synthetic biology, which reminds us of the urgency to disseminate the knowledge of them. Therefore, we set out to disseminate the knowledge to both adults and school students. Various approaches were taken, including handing out pamphlet, giving lectures, and hosting the student visit to iGEM lab.</dd> |
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| − | <dt style="font-weight:400px"><a href="" style="color:#00afd1">Ethetic discussions with the bioethicist</a></dt> | + | <dt style="font-weight:400px"><a href="" style="color:#00afd1">Ethics discussion with the bioethicist</a></dt> |
| − | <dd style="margin-bottom:15px">We’ve conducted a discussion on the ethical issues in synthetic biology and our project with Doctor Xie Guangkuan of the Institute of Medical Humanities of PKU. A comprehensive assessment on the ethical problems of our project has been achieved after the discussion.</dd> | + | <dd style="margin-bottom:15px">We first discussed with Doctor Xie Guangkuan, a researcher from the Institute of Medical Humanities of Peking University, about the ethical issues of synthetic biology, especially about our project. Then, a comprehensive assessment on the ethical problems of our project was performed after the discussion.</dd> |
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| − | <dt style="font-weight:400px"><a href="" style="color:#00afd1">Organization of CCiC</a></dt> | + | <dt style="font-weight:400px"><a href="" style="color:#00afd1">Economic assessment of our device</a></dt> |
| − | <dd style="margin-bottom:15px">From August 14th to 15th, Conference of China iGEMer Committee (CCiC) was held in Peking University. 34 teams, more than 300 iGEMers from all over China have attended this meeting, making it an excellent academic meet-up in the history of iGEM in China. | + | <dd style="margin-bottom:15px">In our project a device for TB diagnosis was manufactured. Therefore, an economic assessment of the device was first performed. Then we interviewed clinical doctors, laboratory workers, and patients for investigating the market demand. This has guided our project toward a more practical direction. |
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