Difference between revisions of "Team:Toulouse"

 
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<center><img src="https://static.igem.org/mediawiki/2015/2/2e/TLSE_ApiColi.png" style="width:30%;"></center>
 
<center><img src="https://static.igem.org/mediawiki/2015/2/2e/TLSE_ApiColi.png" style="width:30%;"></center>
 
    
 
    
<p class="center" style="font-size:15px;"><i>"Beware varroa: Apicoli is guarding the beehive!!"
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<p class="center" style="font-size:15px;"><i>"Beware varroa: Apicoli is guarding the beehive!"
 
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<i>Apis mellifera</i>, the most efficient and widespread honey producing species, is heavily affected by the mite <i>Varroa destructor</i>. This pathogen is actually one of the most important cause of death for domestic bees. Indeed, according to beekeepers, up to 50% of the swarms can be lost every year because of this parasite, causing tremendous economic damages.<br><br>
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<i>Apis mellifera</i>, the most efficient and widespread honey producing species, is heavily affected by the mite <i>Varroa destructor</i>.  
 +
This pathogen is actually one of the most important cause of death for domestic bees. Indeed, according to beekeepers, up to 50% of  
 +
the swarms can be lost every year because of this parasite, causing tremendous economic damages.<br><br>
  
  
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Our team is committed to preserving honeybees by limiting infection of beehives by these mites. The aim of our project is to create a bacterium able to bait and eliminate the parasite using the Synthetic Biology tools and philosophy. The engineered bacterium, named ApiColi, will be safely placed in a trap and will express alternatively an attractant molecule and a poison for the <i>Varroa destructor</i>, in agreement with the honeybee life cycle. Our trap will be sealed to avoid any contact of the microorganism with the bees and the environment. We hope that our concept will help to reduce the decrease in bee populations and its disastrous consequences.<br><br><br><br>
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Our team is committed to preserving honeybees by limiting infection of beehives by these mites.  
 +
The aim of our project is to create a bacterium able to bait and eliminate the parasite using the  
 +
Synthetic Biology tools and philosophy. The engineered bacterium, named ApiColi, will be safely placed in a trap and will express alternatively an attractant molecule and a poison for the <i>Varroa destructor</i>, in agreement with the honeybee life cycle. Our trap will be sealed to avoid any contact of the microorganism with the bees and the environment. We hope that our concept will help to reduce the decrease in bee populations and its disastrous consequences.<br><br><br><br>
 
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</p>
 
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   <h3><strong>Achievements</strong></h3>
 
   <h3><strong>Achievements</strong></h3>
 
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<ul><ul><ul>
 
<ul><ul><ul>
 
  <ul align="justify" style="font-size:15px;">
 
  <ul align="justify" style="font-size:15px;">
<li>Register for iGEM </li>
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<li>Register to iGEM </li>
<li>Complete judjing form</li>
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<li>Complete <a target="blank" href="https://igem.org/2015_Judging_Form?id=1587"> judging form</a></li>
<li>Wiki & Registry</li>
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<li>Wiki & Registry (from <a target="blank" href="https://2015.igem.org/Team:Toulouse/Parts">BBa_K1587000 to BBa_K1587009</a>)</li>
<li>Participating in Giant Jamboree </li>
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<li>Participate to Giant Jamboree </li>
<li>Attributions</li>
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<li><a target="blank" href="https://2015.igem.org/Team:Toulouse/Attributions"> Attributions:</a> our project could be
<li>Add new BioBrick to the Registry: BBa_K1587004 corresponds to butyrate pathway </li>
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possible thanks to several persons who helped us in different ways and we are very grateful</li>
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<li>Add new BioBrick to the Registry: <a target="blank" href="http://parts.igem.org/Part:BBa_K1587004"> BBa_K1587004</a> corresponds to <a target="blank" href="https://2015.igem.org/Team:Toulouse/Description/Attract#part3"> butyrate pathway</a> </li>
 
</ul>
 
</ul>
 
</ul></ul></ul>
 
</ul></ul></ul>
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<ul><ul><ul>
 
<ul><ul><ul>
 
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<li>New BioBrick validated experimentally: BBa_K1587007 corresponds to formate pathway </li>
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<li>New BioBrick validated experimentally: <a target="blank" href="http://parts.igem.org/Part:BBa_K1587007"> BBa_K1587007</a> corresponds to <a target="blank" href="https://2015.igem.org/Team:Toulouse/Description/Eradicate#part2">formate pathway</a> </li>
<li>BioBrick BBa_K1587007 submitted to the Registry</li>
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<li>BioBrick <a target="blank" href="http://parts.igem.org/Part:BBa_K1587007"> BBa_K1587007</a> submitted to the Registry</li>
<li>Practices: Ethics, Safety, IP rights, Education </li>
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<li>Strong commitment to <a target="blank" href="https://2015.igem.org/Team:Toulouse/Practices">Practices:</a> Ethics, Safety, IP rights, Education </li>
 
 
 
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</ul>
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  <ul align="justify" style="font-size:15px;">
 
  <ul align="justify" style="font-size:15px;">
 
   
 
   
<li>Human practices: </li>
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<li>Innovative human practices: </li>
<ul type="circle">
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<ul>
<li>Active participating in ExpoScience, the french one and the international in Brussels</li>
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<strong>-</strong> Active participating in <a target="blank" href="https://2015.igem.org/Team:Toulouse/Practices#Exp2">ExpoScience international</a> in Brussels and future <a target="blank" href="https://2015.igem.org/Team:Toulouse/Practices#Exc">exciting perspectives</a><br>
<li>Strong ethical reflexion</li>
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<strong>-</strong> Our project is based on a <b>deep</b><a target="blank" href="https://2015.igem.org/Team:Toulouse/Practices#Ethical"> Ethical reflection</a><br>
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<strong>-</strong> <a target="blank" href="https://2015.igem.org/Team:Toulouse/Practices#Press">Discussions with beekeepers</a> to fit the best with real issue<br>
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<strong>-</strong> <a target="blank" href="https://2015.igem.org/Team:Toulouse/Practices#Com">Communication in Junior high school</a><br>
 
</ul>
 
</ul>
<li>Collaborations: </li>
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<li><a target="blank" href="https://2015.igem.org/Team:Toulouse/Collaborations#collab">Collaborations:</a> </li>
<ul type="circle">
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<ul>
<li>Modelling with KU Leuven team: they helepd us with a diffusion modelling and we model metabolites production for them</li>
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<strong>-</strong> Modelling with KU Leuven team: they helped us with a <a target="blank" href="https://2015.igem.org/Team:Toulouse/Modeling#part5">diffusion modeling</a> and we model <a target="blank" href="https://2015.igem.org/Team:KU_Leuven/Modeling/Toulouse"> metabolites production</a> for them<br>
<li>Survey with HS Ankara team: they work on varroas too, so we exchanged data from our respective country on varroas infestation </li>
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<strong>-</strong> <a target="blank" href="https://2015.igem.org/Team:Toulouse/Collaborations#ankara">Survey with METU HS Ankara team:</a> they worked on varroas too, so we exchanged data from our respective country on varroas infestation <br>
 
</ul>
 
</ul>
 
 

Latest revision as of 02:18, 19 September 2015

iGEM Toulouse 2015

"Beware varroa: Apicoli is guarding the beehive!"

Easter egg



Apis mellifera, the most efficient and widespread honey producing species, is heavily affected by the mite Varroa destructor. This pathogen is actually one of the most important cause of death for domestic bees. Indeed, according to beekeepers, up to 50% of the swarms can be lost every year because of this parasite, causing tremendous economic damages.

35%

Percentage of hives disapearing every year in the US*

  • *INRA
  • 70%

    Honey production loss in France since 1995*

  • *UNAF
  • 30,000

    Number of hives lost every year in France since 1995*

  • *UNAF

  • Our team is committed to preserving honeybees by limiting infection of beehives by these mites. The aim of our project is to create a bacterium able to bait and eliminate the parasite using the Synthetic Biology tools and philosophy. The engineered bacterium, named ApiColi, will be safely placed in a trap and will express alternatively an attractant molecule and a poison for the Varroa destructor, in agreement with the honeybee life cycle. Our trap will be sealed to avoid any contact of the microorganism with the bees and the environment. We hope that our concept will help to reduce the decrease in bee populations and its disastrous consequences.



    Achievements

      Bronze medal



      Silver medal



      Gold medal