Difference between revisions of "Team:UCL/Playingaround"

 
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{{CSS_UCL5}}
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{{CSS_UCL6}}
 +
 
 
<html>
 
<html>
 
<head>
 
<head>
 +
 +
<script language="JavaScript" type="text/javascript">
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$(document).ready(function(){
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var imgArr = new Array( // relative paths of images
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'https://static.igem.org/mediawiki/2015/c/c3/UCL_block2_1_texture.jpg'
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);
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var preloadArr = new Array();
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var i;
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var currImg = 1;
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var intID = setInterval(changeImg, 2000);
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/* image rotator */
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function changeImg(){
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$('#introo2').animate({opacity: 1}, 1000, function(){
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$(this).css('background','url(' + preloadArr[currImg++%preloadArr.length].src +') no-repeat 1px 40px/100%');
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}).animate({opacity: 1}, 1000);
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}
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});
 +
</script>
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<style>
 
<style>
  
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/*#logophoto {width: 500px; height: 433px; height: 100%; opacity: 1; z-index: 99999;}*/
 
#logophoto {
 
  max-width: 500px;
 
  opacity: 1;
 
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  z-index: 99999;
 
}
 
#logophoto:hover {opacity: 0.7; transition-property: opacity;
 
  transition-duration: 3s;transition-timing-function: ease;}
 
  
#hidden-menu {
+
#topline { width: 100%; height: auto; position: relative; padding: 0; top: 0px; display: block; 
z-index:999;
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-webkit-mask-image: -webkit-gradient(linear, 0 0, 0 100, from(rgba(0,0,0,0.5)), to(rgba(0,0,0,1)));
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animation: topanimation 1s ease-in 1;
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-webkit-animation: topanimation 1s ease-in 1;
 
}
 
}
  
  
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@-webkit-keyframes topanimation {
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    0%  {padding-top: 100px;}
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+
#introo1 {width: 100%; height: 100%; position: relative;
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background: #FBFDFC; background-image: url('https://static.igem.org/mediawiki/2015/e/e1/UCL_block1_texture3.png');   background-repeat: no-repeat; background-position: 0% 0%; background-size: 100%;
 
margin: 0;
 
margin: 0;
padding: 0; vertical-align: middle;
+
padding: 0;
 
font-family: Raleway;
 
font-family: Raleway;
 
letter-spacing: 1.1px; font-size: 13px; top: 0px;
 
letter-spacing: 1.1px; font-size: 13px; top: 0px;
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}
 
}
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#introo1arrow {width: 7%; height: 7%; float: right; display: inline; position: absolute; bottom: 20%; right: 10%; z-index: 10000; opacity: 0.8;}
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background-size: 100%;
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    -moz-transition: opacity 1s;
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z-index: 9996;
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display: block;
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#introo1:hover:after {
 +
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#introo2 {width: 100%; height: 110%; position: relative; top: -100px; margin-top: 100px;
 +
background-image: url('https://static.igem.org/mediawiki/2015/c/c3/UCL_block2_1_texture.jpg');
 +
-webkit-mask-image: -webkit-gradient(linear, 0 40, 0 80, from(rgba(0,0,0,0)), to(rgba(0,0,0,1)));
 +
 +
 +
  background-repeat: no-repeat; background-position: 1px 40px; background-size: 100% ; background-color: no-color;
 +
margin: 0;
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padding: 0;
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font-family: Raleway;
 +
letter-spacing: 1.1px; font-size: 13px;
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 +
transition-property: background-image, color, border-color;
 +
  transition-duration: 0.2s;
 +
  transition-timing-function: ease-in;
 +
z-index: 9997;
 +
}
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 +
#introo2text {position: absolute; bottom: 20%; right: 10%; width: 65%; font-size: 23px; letter-spacing: 2.5px; line-height: 2.1; float: right; display: inline; z-index: 9999;}
 +
 +
#introo2arrow {width: 7%; height: 17%; float: left; display: inline; position: absolute; bottom: 10%; left: 7%; z-index: 9999; opacity: 0.8;}
 +
 +
 +
#introo2:after {
 +
    content: "";
 +
    position: absolute;
 +
    right: 0px;
 +
    left: 0px;
 +
bottom: 0px;
 +
height: 100px !important;
 +
background-image: url('https://static.igem.org/mediawiki/2015/1/15/UCL_block3_texture3.jpg');
 +
-webkit-mask-image: -webkit-gradient(linear, 0 0, 0 80, from(rgba(0,0,0,0)), to(rgba(0,0,0,1)));
 +
display: block;
 +
background-size: 100%;
 +
background-position: 1px 55%;
 +
background-repeat: no-repeat;
 +
    -webkit-transition: opacity 1s;
 +
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 +
    opacity: 0.3;
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z-index: 9998;
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}
 +
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#introo2:hover:after {
 +
    opacity: 1; z-index: 9998;
 +
}
 +
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 +
#introo3 {width: 100%; height: 110%; position: relative; top: -200px;
 +
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background-image: url('https://static.igem.org/mediawiki/2015/1/15/UCL_block3_texture3.jpg');
 +
-webkit-mask-image: -webkit-gradient(linear, 0 0, 0 80, from(rgba(0,0,0,0)), to(rgba(0,0,0,1)));
 +
 +
 +
background-repeat: no-repeat; background-position: left 0px bottom 0px; background-size: 100%;
 +
margin: 0;
 +
padding: 0;
 +
font-family: Raleway;
 +
letter-spacing: 1.1px; font-size: 13px; z-index: 9999; margin-bottom: 118px;
 +
 +
 +
}
 +
 +
#introo3text {position: absolute; top: 14%; right: 10%; width: 80%; font-size: 19px; letter-spacing: 2.2px; line-height: 1.5; float: right; display: inline; z-index: 10001;}
 +
 +
 +
#intro3dnawrap {position: absolute; bottom: 37%; width: 100%;}
 +
#introo3dna {background-image: url('https://static.igem.org/mediawiki/2015/a/ab/UCL_Gearicon.png'); background-size: 100%; background-repeat: no-repeat; background-position: center center; margin: 0 auto; width: 8%; position: relative; left: -21%; opacity: 0.7;
 +
 +
-webkit-animation-name: spinnerRotate;
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    -webkit-animation-duration: 10s;
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    -webkit-animation-timing-function: linear;
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    -moz-animation-name: spinnerRotate;
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    -moz-animation-duration: 10s;
 +
    -moz-animation-iteration-count: infinite;
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    -moz-animation-timing-function: linear;
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    -ms-animation-duration: 10s;
 +
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    -ms-animation-timing-function: linear;
 +
z-index: 10001;
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}
 +
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 +
#todescription {position: absolute; bottom: 10%; width: 100%;}
 +
#centerbutton {position: relative; margin: 0 auto; width: 17%; left: 10px; transition-property: opacity;
 +
  transition-duration: 2s;transition-timing-function: ease;}
 +
#centerbutton:hover {opacity: 0.5; transition-property: opacity;
 +
  transition-duration: 2s;transition-timing-function: ease; }
 +
 +
@media (max-width:1024px){
 +
#introo1 {}
 +
#introo2 { height: 100%;}
 +
#introo3 {height: 100%; background-position: left 0px bottom -35px;}
 +
#introo1text, #introo1arrow {font-size: 18px; line-height: 1.5;}
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#introo2text {font-size: 20px; line-height: 1.5; bottom: 15%;}
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#introo3text {font-size: 17px; line-height: 1.3; top: 22%;}
 +
#todescription {bottom: 3%;}
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#intro3dnawrap {bottom: 29%;}
 +
}
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 +
@media (max-width:768px){
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#introo1 {background-position: 0 100px;}
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#introo1text {font-size: 18px; line-height: 1.5; bottom: 10%;}
 +
#introo2text {font-size: 20px; line-height: 1.5; bottom: 10%;}
 +
#introo1arrow, #introo2arrow {width: 10%; height: 10%;}
 +
#todescription {bottom: 1%;}
 +
#intro3dnawrap {bottom: 21%;}
 +
 +
 +
 +
}
 +
 +
@media (max-width:480px){
 +
#introo1 {background-position: 0 100px;}
 +
#introo1text {font-size: 15px; line-height: 1.3;}
 +
#introo2text {font-size: 17px; line-height: 1.5; bottom: 20%;}
 +
#introo1arrow, #introo2arrow {width: 13%; height: 13%;}
 +
#introo2arrow {bottom: 20%;}
 +
#todescription {bottom: 5%;}
 +
#intro3dnawrap {bottom: 20%;}
 +
#introo1:after {background-image: none;}
 +
#centerbutton {width: 35%; bottom: -20px;}
 +
#introo3 {height: 110%; background-position: left 0px bottom 30px; background-color: #F2ECE4;}
 +
#introo3text {font-size: 14px; line-height: 1.4; top: 22%;}
 +
 +
 +
 +
}
 +
 +
 +
@media (max-width:360px){
 +
#introo1 {background-position: 0 50px; height: 110%;}
 +
#introo1:after {background-image: none;}
 +
#introo1text {font-size: 13px; line-height: 1.1; bottom: 16%;}
 +
#introo2text {font-size: 15px; line-height: 1.3; bottom: 17%;}
 +
#introo1arrow, #introo2arrow {width: 15%; height: 15%;}
 +
#introo3text {font-size: 13px; line-height: 1.3; top: 22%;}
 +
#centerbutton {width: 50%; bottom: -20px;}
 +
#introo3 {height: 110%; background-position: left 0px bottom 30px; background-color: #F2ECE4;}
 +
#intro3dnawrap {bottom: 20%;}
 +
 +
}
 +
 +
 +
@-webkit-keyframes spinnerRotate
 +
{
 +
    from{-webkit-transform:rotate(0deg);}
 +
    to{-webkit-transform:rotate(360deg);}
 +
}
 +
@-moz-keyframes spinnerRotate
 +
{
 +
    from{-moz-transform:rotate(0deg);}
 +
    to{-moz-transform:rotate(360deg);}
 +
}
 +
@-ms-keyframes spinnerRotate
 +
{
 +
    from{-ms-transform:rotate(0deg);}
 +
    to{-ms-transform:rotate(360deg);}
 +
}
 +
 +
 +
 +
#footer {background: #fff; background-size: 100%;  width: 100%; height: 120px; position: fixed; bottom: 0; left: 0; margin: 0 auto;  z-index: -1; }
 +
 +
 +
.intro-buttons2 {text-align: center; position: relative; margin: 0 auto; width: 100%; bottom: -30px; z-index: 9000; }
 +
 +
 +
 +
a.buttonblack2 {
 +
 +
text-transform: uppercase;
 +
  font-size: 30px;
 +
  font-weight: normal;
 +
  line-height: 1.428571429;
 +
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 +
  white-space: nowrap;
 +
  vertical-align: middle;
 +
  border-radius: 10px;
 +
transition-property: background-color, color, border-color;
 +
  transition-duration: 1s;
 +
  transition-timing-function: ease;
 +
  border: solid 5px #19a07c;
 +
    padding: 10px 15px 35px 15px;
 +
  text-decoration: none;
 +
background: none;
 +
font-family: Raleway;
 +
letter-spacing: 4px;
 +
font-weight: bold;
 +
color: #19a07c;
 +
background-image: url('https://static.igem.org/mediawiki/2015/f/fa/UCL_Learnmorearrows.png');
 +
background-size: 15%;
 +
background-position: center bottom 4px;
 +
background-repeat: no-repeat;
 +
animation: logophoto 4s ease-in 1;
 +
-webkit-animation: logophoto 4s ease-in 1;
 +
 +
}
 +
 +
 +
.buttonblack2:hover {  border: solid 5px #065641; color: #19a07c; background: none; }
 +
 +
 +
#header2 {background-image: url('https://static.igem.org/mediawiki/2015/e/e7/UCL_MG_6312_2.png');
 +
text-align: center;
 +
height: 66%;
 +
width:100%;
 +
position: relative;
 +
display: block !important;
 +
margin: 0;
 +
padding: 0;
 +
top: 0;
 +
bottom: 0;
 +
  background-repeat: no-repeat;
 +
 +
  background-size: 100%;
 +
background-position: center center;
 +
background-attachment: fixed;
 +
margin-top: 100px;
 +
-webkit-box-sizing: border-box;
 +
-moz-box-sizing: border-box;
 +
box-sizing: border-box;
 +
 +
vertical-align: middle; }
 +
 +
 +
 +
#logo2 {
 +
padding: 0; position: absolute; height: 100%; left: 0; margin: 0; width: 100%; text-align: left;
 +
}
 +
 +
#logo3 {position: absolute; bottom: 20px; right: 20px;}
 +
 +
 +
 +
 +
#logophoto2 {
 +
margin: 0; padding: 0;
 +
  max-width: 500px;
 +
  width: 100%;
 +
  z-index: 99999;
 +
animation: logophoto 2s ease-in 1;
 +
-webkit-animation: logophoto 2s ease-in 1;
 +
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 +
 +
@-webkit-keyframes logophoto
 +
{ 0% {opacity: 0;}
 +
100% {opacity: 1;}
 +
}
 +
 +
  
 
</style>
 
</style>
 
</head>
 
</head>
 
<body>
 
<body>
<div id="header">
+
<div id="header2">
 
<script>
 
<script>
 
   (function(i,s,o,g,r,a,m){i['GoogleAnalyticsObject']=r;i[r]=i[r]||function(){
 
   (function(i,s,o,g,r,a,m){i['GoogleAnalyticsObject']=r;i[r]=i[r]||function(){
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</script>
 
</script>
  
<div id="logo">
+
<div style="clear: both;"></div>
  
<img src="https://static.igem.org/mediawiki/2015/5/56/UCL_logooo_small.png" id="logophoto" style="" alt="Mind the Gut">  
+
<div id="logo2"><img src="https://static.igem.org/mediawiki/2015/5/56/UCL_logooo_small.png" id="logophoto2" style="" alt="Mind the Gut">  
  
       <div class="intro-buttons" id="box-links">
+
       <div class="intro-buttons2" id="box-links">
         <a data-scroll data-options='{ "easing": "linear" }' href="#introo1" class="buttonblack">Learn more</a>
+
         <a data-scroll data-options='{ "easing": "linear" }' href="#introo1" class="buttonblack2">Learn more</a>
 
   
 
   
 
<br/>
 
<br/>
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</div>
 
</div>
  
 +
<div id="logo3"><img src="https://static.igem.org/mediawiki/2015/e/ea/Ucllogo2.png" style="width: 100px;"></div>
  
  
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</div>
 
</div>
  
<div id="introo1">
 
  
<div id="introo1text">
+
<div id="topline"><img src="https://static.igem.org/mediawiki/2015/d/d0/UCL_Topbar.png.png" style="width: 100%;">
 +
</div>
  
The number of <span style="color: #FE6C68;">microorganisms</span> in human gut is higher than the number of human cells in our body. Their <span style="color: #FE6C68;">metabolic activity</span>  equals that of liver and plays crucial role in many key processes such as <span style="color: #FE6C68;">digestion</span>, <span style="color: #FE6C68;">drug metabolism</span>, or functioning of the <span style="color: #FE6C68;">immune system</span>...
 
  
</div></div>
+
<div id="introo1" class="bgswitch">
  
 +
<div style="clear: both;"></div>
  
 +
<div id="introo1text">
  
 +
The number of <span style="color: #FE6C68;">microorganisms</span> in human gut is higher than the number of human cells in our body. Their <span style="color: #FE6C68;">metabolic activity</span>  equals that of liver and plays crucial role in many key processes such as <span style="color: #FE6C68;">digestion</span>, <span style="color: #FE6C68;">drug metabolism</span>, or functioning of the <span style="color: #FE6C68;">immune system</span>...
  
 
 
<div class="just_text">
 
Studies in mice have shown that the <span style="color: #1E6073;">gut microbiome</span> is also capable of  influencing the chemistry of our brain, thus regulating our <span style="color: #1E6073;">behaviour</span> , <span style="color: #1E6073;">anxiety</span> , <span style="color: #1E6073;">mood</span> , <span style="color: #1E6073;">cognition</span>  and <span style="color: #1E6073;">pain</span> ...
 
 
</div>
 
</div>
  
 +
<div id="introo1arrow">  <a data-scroll data-options='{ "easing": "linear" }' href="#introo2"><img src="https://static.igem.org/mediawiki/2015/f/f7/UCL_Intro1arrow.jpg" style="width: 100%;"></a></div>
  
<div class="just_text">Being inspired by this emerging research area, <span style="color: #019966;">UCL <img src="http://goo.gl/Bt86ec?gdriveurl" style="width: 40px; height: 32px; display: inline;"> 2015</span> team wants to explore the modulation of the gut bacteria as a strategy for developing <span style="color: #019966;">novel treatments</span> for <span style="color: #019966;">mental health</span> disorders. Ultimately, our goal is to harness <span style="color: #019966;">synthetic biology</span> to make people <span style="color: #019966;">happy</span>! </div>
 
 
</div>
 
</div>
 
<div style="clear: both;"></div>
 
  
 
<div class="button-abstract" id="box-links">
 
            <a data-scroll data-options='{ "easing": "linear" }' href="#abstract" class="buttongreen">read abstract</a>
 
</div>
 
  
 
</div>
 
</div>
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 +
<div id="introo2">
  
 
<div style="clear: both;"></div>
 
<div style="clear: both;"></div>
  
<div id="abstract">
+
<div id="introo2text">
<div id="abstracttext">
+
           
+
        <p>        <h2> Mind the Gut: Abstract</h2></p>
+
<p>
+
Current research suggests that gut microbes secrete neuroactive compounds that act on the gut-brain axis and play an important role in healthy brain function. The UCL iGEM team has developed novel synthetic psychobiotics that mimic these neuromodulatory strategies identified in endogenous intestinal strains.
+
  
 +
Studies in mice have shown that the <span style="color: #1E6073;">gut microbiome</span> is also capable of  influencing the chemistry of our brain, thus regulating our <span style="color: #1E6073;">behaviour</span> , <span style="color: #1E6073;">anxiety</span> , <span style="color: #1E6073;">mood</span> , <span style="color: #1E6073;">cognition</span>  and <span style="color: #1E6073;">pain</span> ...
  
 +
</div>
  
 +
<div id="introo2arrow">  <a data-scroll data-options='{ "easing": "linear" }' href="#introo3"><img src="https://static.igem.org/mediawiki/2015/b/b5/Intro2arrow.jpg" style="width: 100%;"></a></div>
 +
</div>
  
 +
<div id="introo3">
  
  
</p>
+
<div id="introo3text">
<p>
+
We have designed safe therapeutic devices that target metabolic pathways for neurochemical biosynthesis. Additionally, we have assessed biocontainment and integrated a sensor detecting mood-related physiological changes in the gut environment.</p>
+
  
<p>
+
Being inspired by this emerging research area, <span style="color: #019966;">UCL iGEM 2015</span> team wants to explore the modulation of the gut bacteria as a strategy for developing <span style="color: #019966;">novel treatments</span> for <span style="color: #019966;">mental health</span> disorders. Ultimately, our goal is to  <span style="font-size: 130%;">harness <span style="color: #019966;">synthetic biology</span> to make people <span style="color: #019966;">happy</span>! </span>
In any year, mental health conditions affect one in four of us and available small molecule treatments have associated stigma and side effects. We believe that, besides aiding in the better understanding of the communication between gut microbiota and brain, our work will also lay a foundation for novel user-friendly treatments for mental health conditions.</p>
+
  
  
<div style="clear: both;"></div>
+
</div>
  
 +
<div id="intro3dnawrap">
 +
<div id="introo3dna"><img src="https://static.igem.org/mediawiki/2015/4/4a/UCL_Dnaicon.png" style="width: 100%;"></div>
 +
</div>
  
  
        </div>
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<div id="todescription"><div id="centerbutton"><a href="https://2015.igem.org/Team:UCL/Description" ><img src="https://static.igem.org/mediawiki/2015/9/93/UCL_mtg_green.png" style="width: 100%; position: relative;"></a></div> </div>
  
  
 
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Latest revision as of 00:49, 26 August 2015

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The number of microorganisms in human gut is higher than the number of human cells in our body. Their metabolic activity equals that of liver and plays crucial role in many key processes such as digestion, drug metabolism, or functioning of the immune system...
Studies in mice have shown that the gut microbiome is also capable of influencing the chemistry of our brain, thus regulating our behaviour , anxiety , mood , cognition and pain ...
Being inspired by this emerging research area, UCL iGEM 2015 team wants to explore the modulation of the gut bacteria as a strategy for developing novel treatments for mental health disorders. Ultimately, our goal is to harness synthetic biology to make people happy!