Difference between revisions of "Team:UC Davis/Practices"

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<b>Overview</b>
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<big><big><b>Overview</b></big></big>
  
 
<br><br>From the start our main objective was to investigate how we could leverage technology to promote more responsible chemical use. Our initial idea was to develop biotechnologies that enable consumers to identify toxins in their environment. The motivation was simple: if people had a device that let them “see” the hazards around them, they might be compelled to reduce the abundance of these chemicals. We decided to test our idea on the commonly used antimicrobial triclosan. However we soon discovered that realizing our good intentions would not be so straightforward.<br><br>
 
<br><br>From the start our main objective was to investigate how we could leverage technology to promote more responsible chemical use. Our initial idea was to develop biotechnologies that enable consumers to identify toxins in their environment. The motivation was simple: if people had a device that let them “see” the hazards around them, they might be compelled to reduce the abundance of these chemicals. We decided to test our idea on the commonly used antimicrobial triclosan. However we soon discovered that realizing our good intentions would not be so straightforward.<br><br>
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We realized that a measurement tool alone would not drive change in responsible chemical use. The tool could be one critical element but we would need to think carefully about where this tool might be most effective and what additional resources would be needed to complement it. <br><br>
 
We realized that a measurement tool alone would not drive change in responsible chemical use. The tool could be one critical element but we would need to think carefully about where this tool might be most effective and what additional resources would be needed to complement it. <br><br>
  
<b>Selecting the target: Triclosan</b>
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<big><big><b>Selecting the target: Triclosan</b></big></big>
  
 
<br><br>Triclosan is an antimicrobial compound that is found in a myriad of consumer products. It is touted as a value added product, however its benefits are largely outweighed by its <a href="https://static.igem.org/mediawiki/2015/8/83/UCDavis_TriclosanFactsheet.pdf">negative environmental impact and potential human health risks</a>. In recent years major companies have been phasing triclosan out of their products in response to negative media attention. We decided to develop biotechnology tools for triclosan because it is a chemical that is very much in the public eye.<br><br>
 
<br><br>Triclosan is an antimicrobial compound that is found in a myriad of consumer products. It is touted as a value added product, however its benefits are largely outweighed by its <a href="https://static.igem.org/mediawiki/2015/8/83/UCDavis_TriclosanFactsheet.pdf">negative environmental impact and potential human health risks</a>. In recent years major companies have been phasing triclosan out of their products in response to negative media attention. We decided to develop biotechnology tools for triclosan because it is a chemical that is very much in the public eye.<br><br>
  
<b>The importance of legislation: How do you encourage chemical monitoring if it is not required?</b>
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<big><big><b>The importance of legislation: How do you encourage chemical monitoring if it is not required?</b></big></big>
  
 
<br><br>We first approached Michael Fan, the manager of the UC Davis wastewater treatment plant to explore the potential use of a biosensor at his and other wastewater treatment facilities. After all, wastewater treatment plants handle most household and city runoff in urban areas where triclosan use is thought to be highest. This engineered chokepoint in the release of triclosan into the broader environment seemed like an ideal place to intervene. And Michael Fan was interested in exploring the idea. What we ultimately learned, however, shifted our focus and some of our design criteria.
 
<br><br>We first approached Michael Fan, the manager of the UC Davis wastewater treatment plant to explore the potential use of a biosensor at his and other wastewater treatment facilities. After all, wastewater treatment plants handle most household and city runoff in urban areas where triclosan use is thought to be highest. This engineered chokepoint in the release of triclosan into the broader environment seemed like an ideal place to intervene. And Michael Fan was interested in exploring the idea. What we ultimately learned, however, shifted our focus and some of our design criteria.
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<br><br>This discovery further highlighted the complexity of the core issue. Targeting just one node in this interconnected network of players would not suffice in resolving the issue; however some players appear to have more influence on the network. In the context of chemical regulation, legislative bodies seem to carry more clout; and strategically targeting this node seemed like a more fruitful course of action.<br><br>
 
<br><br>This discovery further highlighted the complexity of the core issue. Targeting just one node in this interconnected network of players would not suffice in resolving the issue; however some players appear to have more influence on the network. In the context of chemical regulation, legislative bodies seem to carry more clout; and strategically targeting this node seemed like a more fruitful course of action.<br><br>
  
<b>The importance of public awareness</b>
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<big><big><b>The importance of public awareness</b></big></big>
  
 
<br><br>To understand how we could apply pressure to the network to influence policy, we studied famous chemical regulation case studies to see what we might learn from the past. We also reached out to experts to figure out what is and still needs to be done to address the issue presently.<br><br>
 
<br><br>To understand how we could apply pressure to the network to influence policy, we studied famous chemical regulation case studies to see what we might learn from the past. We also reached out to experts to figure out what is and still needs to be done to address the issue presently.<br><br>
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<a href=" https://static.igem.org/mediawiki/2015/2/21/UCDavis_PolicyPracticesSupplemental.pdf "><i>Click here to read more about our research on the history of chemical regulation, conversations with experts, and civic engagement case studies!</i></a><br><br>
 
<a href=" https://static.igem.org/mediawiki/2015/2/21/UCDavis_PolicyPracticesSupplemental.pdf "><i>Click here to read more about our research on the history of chemical regulation, conversations with experts, and civic engagement case studies!</i></a><br><br>
  
<b>Targeting the right nodes in the network</b>
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<big><big><b>Targeting the right nodes in the network</b></big></big>
  
 
<br><br>We were particularly inspired by Greg Neimeyer’s Black Cloud initiative, which effectively inspired a new cohort of environmental stewards at L.A.'s Manual Arts High School. As a result, we decided to focus our efforts on high school students as well.<br><br>
 
<br><br>We were particularly inspired by Greg Neimeyer’s Black Cloud initiative, which effectively inspired a new cohort of environmental stewards at L.A.'s Manual Arts High School. As a result, we decided to focus our efforts on high school students as well.<br><br>
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<a href="https://2015.igem.org/Team:UC_Davis/Design#Lesson_Plan"><i>Read more about our lesson plan development here!</i></a><br><br>
 
<a href="https://2015.igem.org/Team:UC_Davis/Design#Lesson_Plan"><i>Read more about our lesson plan development here!</i></a><br><br>
  
<b>Extending our solution more broadly</b>
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<big><big><b>Extending our solution more broadly</b></big></big>
  
 
<br><br>We then took a step back to assess the possible implications of our lesson plan. We harkened back to Bruce Hammock’s warning about playing into consumer fears and Arlene Blum’s sentiment about the futile cycle of replacing one toxic chemical with another. Cognizant of these two points, we developed an, “Antimicrobial Footprint App,” that prompts users to think deeper about their consumer choices—not to eschew the use of chemicals altogether.   
 
<br><br>We then took a step back to assess the possible implications of our lesson plan. We harkened back to Bruce Hammock’s warning about playing into consumer fears and Arlene Blum’s sentiment about the futile cycle of replacing one toxic chemical with another. Cognizant of these two points, we developed an, “Antimicrobial Footprint App,” that prompts users to think deeper about their consumer choices—not to eschew the use of chemicals altogether.   
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<br><br><a href=" https://2015.igem.org/Team:UC_Davis/Design#Footprint_App"><i>Read more about our Antimicrobial Footprint App here!</i></a><br><br>
 
<br><br><a href=" https://2015.igem.org/Team:UC_Davis/Design#Footprint_App"><i>Read more about our Antimicrobial Footprint App here!</i></a><br><br>
  
<b>Summary: Understanding the complexities of our problem space helped refine our objectives and define our solutions</b>
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<big><big><b>Summary: Understanding the complexities of our problem space helped refine our objectives and define our solutions</b></big></big>
  
 
<br><br>While our initial aspirations of developing a biotechnology tool to promote more responsible chemical use was noble, it wasn’t until we began researching our problem space that we were able to identify a set of specific problems, a strategy, and individual solutions that we thought could be addressed over the summer. <br><br>
 
<br><br>While our initial aspirations of developing a biotechnology tool to promote more responsible chemical use was noble, it wasn’t until we began researching our problem space that we were able to identify a set of specific problems, a strategy, and individual solutions that we thought could be addressed over the summer. <br><br>

Revision as of 00:18, 21 December 2015

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