Difference between revisions of "Team:TU Delft/Description"

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<h2> Project Description </h2>
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<h2> Project Description - The 3D Micro(be) Printing Idea</h2>
  
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<p>Tell us about your project, describe what moves you and why this is something important for your team.</p>
 
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<br />
 
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<h5>What should this page contain?</h5>
 
 
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<li> A clear and concise description of your project.</li>
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<li> Different species of bacteria, algae and fungi can produce biofilms. Biofilms
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<li>A detailed explanation of why your team chose to work on this particular project.</li>
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are microorganisms living in cell clusters on surfaces, such as dental placque.
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<li>References and sources to document your research.</li>
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Within a biofilm the microorganism benefits from increased protection from
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<li>Use illustrations and other visual resources to explain your project.</li>
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antibiotics and the immune system.
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</li>
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<li>Antibiotic resistance and insufficient methods for removing biofilms are still an
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issue, for example in medical implantations. Hence, profound investigation of
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biofilm formation and its removal is essential in medical sciences and commercial
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products.</li>
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<li>
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We will engineer bacteria that can be linked to each other through nanowires
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with the goal of generating a well-defined biofilm structure using a 3D printer.
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The fast and efficient formation of a biofilm using a 3D printer promises
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improved reproducibility and experiment consistency, which may lead to
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advances in anti-biofilm products.</li>
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<li>Another novel application of this technique is the immobilization of enzymes
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on the nanowires using affinity binding, which overcomes substrate uptake
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limitations by cells and improves reusability of the enzymes.
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</li>
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<li> The mechanical stability and adhesive properties can be improved by integrating
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this technique with specific mussel proteins, which are employed by nature to
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attach the mussel to surfaces as an underwater adhesive. We envision this to be
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used in medical applications and environmental biotechnology.</li>
 
</ul>
 
</ul>
  

Revision as of 09:28, 20 May 2015

Project Description - The 3D Micro(be) Printing Idea

  • Different species of bacteria, algae and fungi can produce biofilms. Biofilms are microorganisms living in cell clusters on surfaces, such as dental placque. Within a biofilm the microorganism benefits from increased protection from antibiotics and the immune system.
  • Antibiotic resistance and insufficient methods for removing biofilms are still an issue, for example in medical implantations. Hence, profound investigation of biofilm formation and its removal is essential in medical sciences and commercial products.
  • We will engineer bacteria that can be linked to each other through nanowires with the goal of generating a well-defined biofilm structure using a 3D printer. The fast and efficient formation of a biofilm using a 3D printer promises improved reproducibility and experiment consistency, which may lead to advances in anti-biofilm products.
  • Another novel application of this technique is the immobilization of enzymes on the nanowires using affinity binding, which overcomes substrate uptake limitations by cells and improves reusability of the enzymes.
  • The mechanical stability and adhesive properties can be improved by integrating this technique with specific mussel proteins, which are employed by nature to attach the mussel to surfaces as an underwater adhesive. We envision this to be used in medical applications and environmental biotechnology.

Advice on writing your Project Description

We encourage you to put up a lot of information and content on your wiki, but we also encourage you to include summaries as much as possible. If you think of the sections in your project description as the sections in a publication, you should try to be consist, accurate and unambiguous in your achievements.

Judges like to read your wiki and know exactly what you have achieved. This is how you should think about these sections; from the point of view of the judge evaluating you at the end of the year.


References

iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you though about your project and what works inspired you.

Inspiration

See how other teams have described and presented their projects: