Difference between revisions of "Team:San Andres/Software"

 
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          <a href="https://2015.igem.org/Team:San_Andres" style="color: rgb(0, 0, 0);">Home </a>
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          <a href="https://2015.igem.org/Team:San_Andres/Team" style="color: rgb(0, 0, 0);"> Team</a>
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          <a href="https://2015.igem.org/Team:San_Andres/Description" style="color: rgb(0, 0, 0);"> Project</a>
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        </td>
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          <a href="https://2015.igem.org/Team:San_Andres/Parts" style="color: rgb(0, 0, 0);"> Parts</a>
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        </td>
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          <a href="https://2015.igem.org/Team:San_Andres/Modeling" style="color: rgb(0, 0, 0);"> Modeling</a>
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        </td>
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        <td style="border: 3px solid #1d1003;" align="center" bgcolor="#ffee1b" height="30" onmouseout="this.bgColor='#ffee1b'" onmouseover="this.bgColor='#6bb402'"><a href="https://2015.igem.org/Team:San_Andres/Results" style="color: rgb(0, 0, 0);"> Results</a>
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 +
          <a href="https://2015.igem.org/Team:San_Andres/Notebook" style="color: rgb(0, 0, 0);">Notebook</a>
 +
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 +
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 +
          <a href="https://2015.igem.org/Team:San_Andres/Practices" style="color: rgb(0, 0, 0);"> Human Practices</a>
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 +
          <a href="https://2015.igem.org/Team:San_Andres/Design" style="color: rgb(0, 0, 0);"> Future Projections</a>
 +
        </td>
 +
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 +
          <a href="https://2015.igem.org/Team:San_Andres/Attributions" style="color: rgb(0, 0, 0);"> Attributions</a>
 +
        </td>
 +
        <td style="border: 3px solid #1d1003;" align="center" bgcolor="#ffee1b" height="30" onmouseout="this.bgColor='#ffee1b'" onmouseover="this.bgColor='#6bb402'">
 +
          <a href="https://2015.igem.org/Team:San_Andres/Collaborations" style="color: rgb(0, 0, 0);"> Collaborations</a>
 +
        </td>
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      </tr>
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    </tbody>
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     <h1>Collaborations</h1>
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     <h1>Abstract</h1>
−
     <big>So the project could be carried out we have the
+
     <div style="text-align: justify;"><big>The celiac
−
collaboration of two teams IGEM (<a href="https://2015.igem.org/Team:Colegio_EmelinaU">EmelinaU</a>
+
disease affects 1 in 265 people worldwide and 15%
−
and&nbsp;<a href="https://2015.igem.org/Team:Liceo_Eugenio_Hostos">Hostos</a>),
+
of population in Chile. This in an irreversible autoimmune disease in
−
since we work together in the same laboratory and share some parts of
+
which due to the presence of genes HLA DQ2 or HLA DQ8 in those
−
our Biobricks. We also have the contribution of teams <a href="https://2011.igem.org/Team:Washington">Washintong 2011</a>
+
affected, the consumption of foods containing gluten (all fods derived
−
and&nbsp;<a href="https://2012.igem.org/Team:Colorado_State/Project">Colorado
+
from wheat, barley, rye, etc.) cause an inflammation in small intestine
−
2012</a> , since their research served as references in our. <br>
+
causing multiple effects in the organism (diarrhea, constipation, porr
−
<br>
+
absorption, among others) significantly affecting their quatily of life.</big>
 +
      <br>
 +
      <br>
 +
      <big>Whereas the majority of the world food contains gluten, we
 +
propose a
 +
treatment for those who can't eat gluten, and can do so without
 +
problems. In detail, our project involves a system able to degrade
 +
gluten via the enzyme KumaMax and report the operation simultaneously
 +
with a red fluorescent protein. The foregoing, works in a genetically
 +
modified E. coli bacteria. With this project, in long run, we hope to
 +
improve the quality of life of all those reported with celiac disease.
 +
People who suffer from gluten intolerance have an adverse reaction to
 +
gluten proteins found in wheat, barley, and rye products.</big>
 +
      <br>
 +
    </div>
 +
    <big><br>
 
</big>
 
</big>
 
     <div style="text-align: center;">
 
     <div style="text-align: center;">
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       <img alt="https://static.igem.org/mediawiki/2015/e/e5/Grupo_800.jpg" src="https://static.igem.org/mediawiki/2015/e/e5/Grupo_800.jpg">
+
       <img style="width: 893px; height: 373px;" alt="File:Ex 2.jpg" src="https://static.igem.org/mediawiki/2015/thumb/9/93/Ex_2.jpg/800px-Ex_2.jpg">
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    <p class="MsoListParagraph" style="text-indent: -18pt;">
 
       <br>
 
       <br>
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      <br>
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    </p>
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      <h1 style="text-align: left;">References</h1>
+
    <p class="MsoListParagraph" style="text-indent: -18pt;"></p>
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      <div style="text-align: left;"><big>1.&nbsp;</big><big>Structural
+
−
Basis for Gluten Intolerance in Celiac Sprue (2002)<br>
+
−
2. Seminar Coeliac Disease (2003)<br>
+
−
3.&nbsp;Mortality in celiac disease (2010)<br>
+
−
4.&nbsp;Crystallographic and Biochemical Investigations of
+
−
Kumamolisin-As, a Serine-Carboxyl Peptidase with Collagenase Activity
+
−
(2004)<br>
+
−
5.&nbsp;Epilepsy, cerebral calcifications and clinical or
+
−
subclinical coeliac disease. Course and follow up with gluten-free diet
+
−
(1998)<br>
+
−
6.&nbsp;Coeliac disease on the rise in Europe (2010)<br>
+
−
7.&nbsp;Should coeliac sufferers be allowed their oats? (2007)<br>
+
−
8.&nbsp;Prevalence of Celiac Disease among Children in Finland
+
−
(2001)<br>
+
−
9.&nbsp;Protein engineering of improved prolyl endopeptidases for
+
−
celiac sprue therapy (2008)<br>
+
−
10. Undiagnosed coeliac disease and risk of autoimmune disorders in
+
−
subjects with Type I diabetes mellitus (2001)<br>
+
−
11.&nbsp;Analytical Methods for Detection of Gluten in Food—Method
+
−
Developments in Support of Food Labeling Legislation (2011)<br>
+
−
<span style="font-weight: bold;"></span></big>
+
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  <br>
 
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   <a href="https://2015.igem.org/Main_Page" class="gwd-a-3xpx gwd-a-36ww">
 
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      <ul>
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        <li><a href="https://2015.igem.org/Team:San_Andres">Home</a>
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−
        </li>
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        <li><a href="https://2015.igem.org/Team:San_Andres/Team">Team</a>
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        </li>
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        <li><a href="https://2015.igem.org/Team:San_Andres/Description">Project</a>
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          <ul>
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            <li><a href="https://2015.igem.org/Team:San_Andres/Parts">Parts</a>
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            </li>
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            <li><a href="https://2015.igem.org/Team:San_Andres/Modeling">Modeling</a>
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            </li>
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            <li><a href="https://2015.igem.org/Team:San_Andres/Results">Results</a>
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          </ul>
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        </li>
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        <li><a href="https://2015.igem.org/Team:San_Andres/Notebook">Notebook</a>
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          <ul>
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            <li><a href="https://2015.igem.org/Team:San_Andres/Practices">Human Practices</a>
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            </li>
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            <li><a href="https://2015.igem.org/Team:San_Andres/Design">Future Projections</a>
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            </li>
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          </ul>
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−
        </li>
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        <li><a href="https://2015.igem.org/Team:San_Andres/Collaborations">Collaborations</a>
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Latest revision as of 01:22, 15 September 2015

<endnote><head> <title><endnote><head> <meta> <title> wiki wiki exp wiki wiki wiki 2   File:Gluten-s-Job.jpeg

Home Team Project Parts Modeling Results
Notebook Human Practices Future Projections Attributions Collaborations

Abstract

The celiac disease affects 1 in 265 people worldwide and 15% of population in Chile. This in an irreversible autoimmune disease in which due to the presence of genes HLA DQ2 or HLA DQ8 in those affected, the consumption of foods containing gluten (all fods derived from wheat, barley, rye, etc.) cause an inflammation in small intestine causing multiple effects in the organism (diarrhea, constipation, porr absorption, among others) significantly affecting their quatily of life.

Whereas the majority of the world food contains gluten, we propose a treatment for those who can't eat gluten, and can do so without problems. In detail, our project involves a system able to degrade gluten via the enzyme KumaMax and report the operation simultaneously with a red fluorescent protein. The foregoing, works in a genetically modified E. coli bacteria. With this project, in long run, we hope to improve the quality of life of all those reported with celiac disease. People who suffer from gluten intolerance have an adverse reaction to gluten proteins found in wheat, barley, and rye products.

File:Ex 2.jpg