Difference between revisions of "Team:ANU-Canberra/project"

 
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<h3>Background</h3>
 
<h3>Background</h3>
 
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<p>This year being The International Year of Light and Light-based Technologies, we were inspired to investigate potential uses of light in synthetic biology. One such application is optogenetics. Optogenetics is defined by the control of cellular dynamics using light. It allows for the ability to control the translocation of proteins, transcriptional activation and other potential uses.</p>
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<p>In the International Year of Light, we were inspired to investigate potential uses of light in synthetic biology (optogenetics). We describe a strategy for the use of the photosensitive protein CRY2 to increase yield in the biosynthesis of toxic metabolites.</p>
 
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<h3>Aims</h3>
 
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<p>We are taking part in the Foundational Advance track, exploring the principles and application of light-induction as an alternative to traditional chemical induction.</p>
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<p>We are taking part in the Foundational Advance track, exploring the principles and application of light-induction as an alternative to traditional chemical induction - through experimental work, literature reviews and outreach programs.</p>
 
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<h3>Biosafety</h3>
 
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<p>Safe use of genetically engineered machines involves physical containment, safe practices as well as biocontainment methods to prevent escape, survival and proliferation of engineered microorganisms in natural environments.</p>
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<p>We review an innovate strategy for biocontainment, using genetically recoded organisms that require synthetic amino acids to grow and survive.</p>
 
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<h3>Photobioreactor</h3>
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<p>Addressing the industrial aspect of our, we investigated options for potential bioreactors for bulk synthesis of our target material - NAD. </p>
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Latest revision as of 13:46, 18 September 2015

Our Project

Background

In the International Year of Light, we were inspired to investigate potential uses of light in synthetic biology (optogenetics). We describe a strategy for the use of the photosensitive protein CRY2 to increase yield in the biosynthesis of toxic metabolites.

Aims

We are taking part in the Foundational Advance track, exploring the principles and application of light-induction as an alternative to traditional chemical induction - through experimental work, literature reviews and outreach programs.

Biosafety

We review an innovate strategy for biocontainment, using genetically recoded organisms that require synthetic amino acids to grow and survive.

Photobioreactor

Addressing the industrial aspect of our, we investigated options for potential bioreactors for bulk synthesis of our target material - NAD.