Difference between revisions of "Team:Toulouse"

 
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<center><img src="https://static.igem.org/mediawiki/2015/2/2e/TLSE_ApiColi.png" style="width:30%;"></center>
 
<center><img src="https://static.igem.org/mediawiki/2015/2/2e/TLSE_ApiColi.png" style="width:30%;"></center>
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<p class="center" style="font-size:15px;"><i>"If the bee disappeared off the surface of the globe then man would only have four years of life left. <br>
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<p class="center" style="font-size:15px;"><i>"Beware varroa: Apicoli is guarding the beehive!"
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  No more bees, no more pollination, no more plants, no more animals, no more man."
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       <p class="fl_right"><a class="btn" href="#"> UNAF, 1994.</a></p>-->
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       <p class="fl_right"><a class="btn" href="#" style="color: rgba(0,0,0,0)"> Easter egg </a></p>
 
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         <p align="justify" style="font-size:15px;">
 
         <p align="justify" style="font-size:15px;">
  
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<i>Apis mellifera</i>, the most efficient and widespread honey producing species, is heavily affected by the mite <i>Varroa destructor</i>. This pathogen is actually one of the most important cause of death for domestic bees. Indeed, according to beekeepers, up to 50 % of the swarms can be lost every year, because of this parasite, causing tremendous economic damages to beekeepers.<br><br>
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<i>Apis mellifera</i>, the most efficient and widespread honey producing species, is heavily affected by the mite <i>Varroa destructor</i>.  
 +
This pathogen is actually one of the most important cause of death for domestic bees. Indeed, according to beekeepers, up to 50% of  
 +
the swarms can be lost every year because of this parasite, causing tremendous economic damages.<br><br>
  
  
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       <li><a href="
 
       <li><a href="
 
https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/257834-38b5f-resource-dossier-abeilles.html#page=4
 
https://inra-dam-front-resources-cdn.brainsonic.com/ressources/afile/257834-38b5f-resource-dossier-abeilles.html#page=4
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">INRA</a></li>
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">*INRA</a></li>
 
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<li><a href="
 
<li><a href="
 
http://www.unaf-apiculture.info/presse/Dossier%20de%20presse/DOSSIER_DE_PRESSE_UNAF.pdf#page=7
 
http://www.unaf-apiculture.info/presse/Dossier%20de%20presse/DOSSIER_DE_PRESSE_UNAF.pdf#page=7
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">UNAF</a></li>
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">*UNAF</a></li>
 
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       </div>
 
   
 
   
 
       <div class="one_third">
 
       <div class="one_third">
 
          
 
          
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         <p align="center" style="font-size:50px;">30,000</p> <p align="center" style="font-size:20px;"(Number total of hives > 1,000,000)<br></p>
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         <p align="center" style="font-size:50px;">30,000<br></p>
 
<p align="center" style="font-size:15px;">
 
<p align="center" style="font-size:15px;">
 
Number of hives lost every year in France since 1995*</p>
 
Number of hives lost every year in France since 1995*</p>
 
<li><a href="
 
<li><a href="
 
http://www.unaf-apiculture.info/presse/Dossier%20de%20presse/DOSSIER_DE_PRESSE_UNAF.pdf#page=9
 
http://www.unaf-apiculture.info/presse/Dossier%20de%20presse/DOSSIER_DE_PRESSE_UNAF.pdf#page=9
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">UNAF</a></li>
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">*UNAF</a></li>
 
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<div class="group center">
 
<div class="group center">
 
<p align="justify" style="font-size:15px;">
 
<p align="justify" style="font-size:15px;">
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Our team is committed to preserving honeybees by fighting these mites. The aim of our project is to work out a bacterium capable of baiting and eliminating the parasite using the tools offered by synthetic biology. Our bacteria, named ApiColi, will be safely placed in a trap and will express alternatively an attractant and a poison for the <i>Varroa destructor</i>, in agreement with the honeybee life cycle. Our trap will be sealed to avoid any contact of the microorganism with the bees and the environment. We hope that our concept will help reduce the decrease in bee populations and its disastrous consequences.<br><br><br><br>
+
Our team is committed to preserving honeybees by limiting infection of beehives by these mites.  
 +
The aim of our project is to create a bacterium able to bait and eliminate the parasite using the  
 +
Synthetic Biology tools and philosophy. The engineered bacterium, named ApiColi, will be safely placed in a trap and will express alternatively an attractant molecule and a poison for the <i>Varroa destructor</i>, in agreement with the honeybee life cycle. Our trap will be sealed to avoid any contact of the microorganism with the bees and the environment. We hope that our concept will help to reduce the decrease in bee populations and its disastrous consequences.<br><br><br><br>
 
</p>
 
</p>
 
</div>
 
</div>
  
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<center>
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<div class="title" id="achievements">
 +
  <h3><strong>Achievements</strong></h3>
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  </div>
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</center>
 +
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<table>
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<tbody>
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<tr>
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<td style="width:50px">
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<center>
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<img src="https://static.igem.org/mediawiki/2015/4/41/TLSE_Home_Medals_Bronze.PNG" style="width:100%;" />
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</center>
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</td>
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 +
<td colspan="3">
 +
 
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  <ul><h3><strong>Bronze medal</strong></h3></ul>
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 +
</td>
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</tr>
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</tbody>
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</table>
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 +
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<ul><ul><ul>
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<ul align="justify" style="font-size:15px;">
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<li>Register to iGEM </li>
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<li>Complete <a target="blank" href="https://igem.org/2015_Judging_Form?id=1587"> judging form</a></li>
 +
<li>Wiki & Registry (from <a target="blank" href="https://2015.igem.org/Team:Toulouse/Parts">BBa_K1587000 to BBa_K1587009</a>)</li>
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<li>Participate to Giant Jamboree </li>
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<li><a target="blank" href="https://2015.igem.org/Team:Toulouse/Attributions"> Attributions:</a> our project could be
 +
possible thanks to several persons who helped us in different ways and we are very grateful</li>
 +
<li>Add new BioBrick to the Registry: <a target="blank" href="http://parts.igem.org/Part:BBa_K1587004"> BBa_K1587004</a> corresponds to <a target="blank" href="https://2015.igem.org/Team:Toulouse/Description/Attract#part3"> butyrate pathway</a> </li>
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</ul>
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</ul></ul></ul>
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<br><br>
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<table>
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<tbody>
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<tr>
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<td style="width:50px">
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<center>
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<img src="https://static.igem.org/mediawiki/2015/2/2c/TLSE_Home_Medals_Silver.PNG" style="width:100%;" />
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</center>
 +
</td>
 +
 +
<td colspan="3">
 +
 
 +
  <ul><h3><strong>Silver medal</strong></h3></ul>
 +
 
 +
</td>
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</tr>
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</tbody>
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</table>
 +
 +
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<ul><ul><ul>
 +
<ul align="justify" style="font-size:15px;">
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<li>New BioBrick validated experimentally: <a target="blank" href="http://parts.igem.org/Part:BBa_K1587007"> BBa_K1587007</a> corresponds to <a target="blank" href="https://2015.igem.org/Team:Toulouse/Description/Eradicate#part2">formate pathway</a> </li>
 +
<li>BioBrick <a target="blank" href="http://parts.igem.org/Part:BBa_K1587007"> BBa_K1587007</a> submitted to the Registry</li>
 +
<li>Strong commitment to <a target="blank" href="https://2015.igem.org/Team:Toulouse/Practices">Practices:</a> Ethics, Safety, IP rights, Education </li>
 +
 +
</ul>
 +
</ul></ul></ul>
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<br><br>
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<table>
 +
<tbody>
 +
<tr>
 +
<td style="width:50px">
 +
<center>
 +
<img src="https://static.igem.org/mediawiki/2015/b/b0/TLSE_Home_Medals_Gold.PNG" style="width:100%;" />
 +
</center>
 +
</td>
 +
 +
<td colspan="3">
 +
 
 +
  <ul><h3><strong>Gold medal</strong></h3></ul>
 +
 
 +
</td>
 +
</tr>
 +
</tbody>
 +
</table>
 +
 +
 +
<ul><ul><ul>
 +
<ul align="justify" style="font-size:15px;">
 +
 +
<li>Innovative human practices: </li>
 +
<ul>
 +
<strong>-</strong> Active participating in <a target="blank" href="https://2015.igem.org/Team:Toulouse/Practices#Exp2">ExpoScience international</a> in Brussels and future <a target="blank" href="https://2015.igem.org/Team:Toulouse/Practices#Exc">exciting perspectives</a><br>
 +
<strong>-</strong> Our project is based on a <b>deep</b><a target="blank" href="https://2015.igem.org/Team:Toulouse/Practices#Ethical"> Ethical reflection</a><br>
 +
<strong>-</strong> <a target="blank" href="https://2015.igem.org/Team:Toulouse/Practices#Press">Discussions with beekeepers</a> to fit the best with real issue<br>
 +
<strong>-</strong> <a target="blank" href="https://2015.igem.org/Team:Toulouse/Practices#Com">Communication in Junior high school</a><br>
 +
</ul>
 +
<li><a target="blank" href="https://2015.igem.org/Team:Toulouse/Collaborations#collab">Collaborations:</a> </li>
 +
<ul>
 +
<strong>-</strong> Modelling with KU Leuven team: they helped us with a <a target="blank" href="https://2015.igem.org/Team:Toulouse/Modeling#part5">diffusion modeling</a> and we model <a target="blank" href="https://2015.igem.org/Team:KU_Leuven/Modeling/Toulouse"> metabolites production</a> for them<br>
 +
<strong>-</strong> <a target="blank" href="https://2015.igem.org/Team:Toulouse/Collaborations#ankara">Survey with METU HS Ankara team:</a> they worked on varroas too, so we exchanged data from our respective country on varroas infestation <br>
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</ul>
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 +
</ul>
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</ul></ul></ul>
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<br><br>
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Latest revision as of 02:18, 19 September 2015

iGEM Toulouse 2015

"Beware varroa: Apicoli is guarding the beehive!"

Easter egg



Apis mellifera, the most efficient and widespread honey producing species, is heavily affected by the mite Varroa destructor. This pathogen is actually one of the most important cause of death for domestic bees. Indeed, according to beekeepers, up to 50% of the swarms can be lost every year because of this parasite, causing tremendous economic damages.

35%

Percentage of hives disapearing every year in the US*

  • *INRA

    • 70%

    Honey production loss in France since 1995*

  • *UNAF

    • 30,000

    Number of hives lost every year in France since 1995*

  • *UNAF

    • Our team is committed to preserving honeybees by limiting infection of beehives by these mites. The aim of our project is to create a bacterium able to bait and eliminate the parasite using the Synthetic Biology tools and philosophy. The engineered bacterium, named ApiColi, will be safely placed in a trap and will express alternatively an attractant molecule and a poison for the Varroa destructor, in agreement with the honeybee life cycle. Our trap will be sealed to avoid any contact of the microorganism with the bees and the environment. We hope that our concept will help to reduce the decrease in bee populations and its disastrous consequences.



    Achievements

      Bronze medal


      Silver medal


      Gold medal