Difference between revisions of "Team:Cairo Egypt"
(62 intermediate revisions by the same user not shown) | |||
Line 1: | Line 1: | ||
<html> | <html> | ||
+ | |||
+ | <meta http-equiv="cache-control" content="max-age=0" /> | ||
+ | <meta http-equiv="cache-control" content="no-cache" /> | ||
+ | <meta http-equiv="expires" content="0" /> | ||
+ | <meta http-equiv="expires" content="Tue, 01 Jan 1980 1:00:00 GMT" /> | ||
+ | <meta http-equiv="pragma" content="no-cache" /> | ||
<script> | <script> | ||
Line 5: | Line 11: | ||
</script> | </script> | ||
+ | <link rel="stylesheet" href="https://2015.igem.org/Team:Cairo_Egypt/css/igem_toolbar_style?action=raw&ctype=text/css" type="text/css"> | ||
<link rel="stylesheet" href="https://2015.igem.org/Team:Cairo_Egypt/css/bootstrap?action=raw&ctype=text/css" type="text/css"> | <link rel="stylesheet" href="https://2015.igem.org/Team:Cairo_Egypt/css/bootstrap?action=raw&ctype=text/css" type="text/css"> | ||
<link rel="stylesheet" href="https://2015.igem.org/Team:Cairo_Egypt/css/home_style?action=raw&ctype=text/css" type="text/css"> | <link rel="stylesheet" href="https://2015.igem.org/Team:Cairo_Egypt/css/home_style?action=raw&ctype=text/css" type="text/css"> | ||
Line 19: | Line 26: | ||
<a id="menu-close" href="#" class="btn btn-light btn-lg pull-right toggle"><i class="fa fa-times"></i></a> | <a id="menu-close" href="#" class="btn btn-light btn-lg pull-right toggle"><i class="fa fa-times"></i></a> | ||
<li class="sidebar-brand"> | <li class="sidebar-brand"> | ||
− | <a href="#top" onclick = $("#menu-close").click(); > | + | <a href="#top" onclick = $("#menu-close").click(); >Project ABC</a> |
</li> | </li> | ||
<li> | <li> | ||
Line 28: | Line 35: | ||
</li> | </li> | ||
<li> | <li> | ||
− | <a href="#services" onclick = $("#menu-close").click(); > | + | <a href="#services" onclick = $("#menu-close").click(); >What we have</a> |
− | + | ||
− | + | ||
− | + | ||
</li> | </li> | ||
<li> | <li> | ||
Line 54: | Line 58: | ||
<div class="row"> | <div class="row"> | ||
<div class="col-lg-12 text-center"> | <div class="col-lg-12 text-center"> | ||
− | <h2> | + | <h2>Brief Description</h2> |
<p class="lead">Breast cancer is the most common malignancy in women and constitutes 18% of all female cancers (Jemal et al., 2002) Although there has been a slight decrease in mortality in breast cancer patients (Schiffman et al., 2002), it is not uncommon for even early-stage breast cancer to metastasize. Therefore, novel therapeutic strategies are constantly being pursued (Bange et al., 2001). It has been reported that some bacterial species preferentially replicate and accumulate within tumors. At critical cell densities, the binding of a regulator protein to the signal leads to the switch on of genes controlled by QS and therefore a coordinated population response Moreover, they possess certain advantageous features such as motility, capacity to simultaneously carry and express multiple therapeutic proteins. Its elimination by antibiotics makes it a promising new strategy in cancer treatment. Azurin is a copper-containing redox protein with low molecular Weight which can efficiently induce cell apoptosis by raising the intracellular levels of p53 and Bax. It has been found that Azurin receptors are hyper expressed on the surfaces of cancer cells relative to their expression on the surfaces of normal cells. We do intend to modify genetic material of bacteria species that localize and induce expression of Azurin in presence of tumor only.</p> | <p class="lead">Breast cancer is the most common malignancy in women and constitutes 18% of all female cancers (Jemal et al., 2002) Although there has been a slight decrease in mortality in breast cancer patients (Schiffman et al., 2002), it is not uncommon for even early-stage breast cancer to metastasize. Therefore, novel therapeutic strategies are constantly being pursued (Bange et al., 2001). It has been reported that some bacterial species preferentially replicate and accumulate within tumors. At critical cell densities, the binding of a regulator protein to the signal leads to the switch on of genes controlled by QS and therefore a coordinated population response Moreover, they possess certain advantageous features such as motility, capacity to simultaneously carry and express multiple therapeutic proteins. Its elimination by antibiotics makes it a promising new strategy in cancer treatment. Azurin is a copper-containing redox protein with low molecular Weight which can efficiently induce cell apoptosis by raising the intracellular levels of p53 and Bax. It has been found that Azurin receptors are hyper expressed on the surfaces of cancer cells relative to their expression on the surfaces of normal cells. We do intend to modify genetic material of bacteria species that localize and induce expression of Azurin in presence of tumor only.</p> | ||
− | |||
− | |||
</div> | </div> | ||
</div> | </div> | ||
Line 71: | Line 73: | ||
<div class="row text-center"> | <div class="row text-center"> | ||
<div class="col-lg-10 col-lg-offset-1"> | <div class="col-lg-10 col-lg-offset-1"> | ||
− | <h2> | + | <h2>What we have</h2> |
<hr class="small"> | <hr class="small"> | ||
<div class="row"> | <div class="row"> | ||
Line 78: | Line 80: | ||
<span class="fa-stack fa-4x"> | <span class="fa-stack fa-4x"> | ||
<i class="fa fa-circle fa-stack-2x"></i> | <i class="fa fa-circle fa-stack-2x"></i> | ||
− | <i class="fa fa- | + | <i class="fa fa-group fa-stack-1x text-primary"></i> |
</span> | </span> | ||
<h4> | <h4> | ||
− | <strong> | + | <strong>Team</strong> |
</h4> | </h4> | ||
− | <p> | + | <p>Learn more about the team and the instructors.</p> |
− | <a | + | <a class="btn btn-light" href="https://2015.igem.org/Team:Cairo_Egypt/Team">Learn More</a> |
</div> | </div> | ||
</div> | </div> | ||
Line 91: | Line 93: | ||
<span class="fa-stack fa-4x"> | <span class="fa-stack fa-4x"> | ||
<i class="fa fa-circle fa-stack-2x"></i> | <i class="fa fa-circle fa-stack-2x"></i> | ||
− | <i class="fa fa- | + | <i class="fa fa-file-text-o fa-stack-1x text-primary"></i> |
</span> | </span> | ||
<h4> | <h4> | ||
− | <strong> | + | <strong>Description</strong> |
</h4> | </h4> | ||
− | <p> | + | <p>Learn more about project and results.</p> |
− | <a href=" | + | <a href="https://2015.igem.org/Team:Cairo_Egypt/Description" class="btn btn-light">Learn More</a> |
</div> | </div> | ||
</div> | </div> | ||
Line 107: | Line 109: | ||
</span> | </span> | ||
<h4> | <h4> | ||
− | <strong> | + | <strong>Experiments</strong> |
</h4> | </h4> | ||
− | <p> | + | <p>Learn more about project and experiments and protocols.</p> |
− | <a href=" | + | <a href="https://2015.igem.org/Team:Cairo_Egypt/Experiments" class="btn btn-light">Learn More</a> |
</div> | </div> | ||
</div> | </div> | ||
Line 117: | Line 119: | ||
<span class="fa-stack fa-4x"> | <span class="fa-stack fa-4x"> | ||
<i class="fa fa-circle fa-stack-2x"></i> | <i class="fa fa-circle fa-stack-2x"></i> | ||
− | <i class="fa fa- | + | <i class="fa fa-bar-chart fa-stack-1x text-primary"></i> |
</span> | </span> | ||
<h4> | <h4> | ||
− | <strong> | + | <strong>Results</strong> |
</h4> | </h4> | ||
− | <p> | + | <p>Learn more about project and results.</p> |
− | <a href=" | + | <a href="https://2015.igem.org/Team:Cairo_Egypt/Results" class="btn btn-light">Learn More</a> |
</div> | </div> | ||
</div> | </div> | ||
− | + | <div class="col-md-3 col-sm-6"> | |
− | + | <div class="service-item"> | |
− | + | <span class="fa-stack fa-4x"> | |
− | + | <i class="fa fa-circle fa-stack-2x"></i> | |
− | + | <i class="fa fa-gears fa-stack-1x text-primary"></i> | |
− | + | </span> | |
− | + | <h4> | |
− | + | <strong>Parts</strong> | |
− | + | </h4> | |
− | + | <p>Know more about parts here used in the project.</p> | |
− | + | <a href="https://2015.igem.org/Team:Cairo_Egypt/Parts" class="btn btn-light">Learn More</a> | |
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | + | ||
− | <a href=" | + | |
− | + | ||
− | + | ||
</div> | </div> | ||
</div> | </div> | ||
− | <div class="col-md-6"> | + | <div class="col-md-3 col-sm-6"> |
− | <div class=" | + | <div class="service-item"> |
− | < | + | <span class="fa-stack fa-4x"> |
− | + | <i class="fa fa-circle fa-stack-2x"></i> | |
− | </a> | + | <i class="fa fa-futbol-o fa-stack-1x text-primary"></i> |
+ | </span> | ||
+ | <h4> | ||
+ | <strong>Practices</strong> | ||
+ | </h4> | ||
+ | <p>Learn more about human practice here.</p> | ||
+ | <a href="https://2015.igem.org/Team:Cairo_Egypt/Practices" class="btn btn-light">Learn More</a> | ||
</div> | </div> | ||
</div> | </div> | ||
− | <div class="col-md-6"> | + | <div class="col-md-3 col-sm-6"> |
− | <div class=" | + | <div class="service-item"> |
− | < | + | <span class="fa-stack fa-4x"> |
− | + | <i class="fa fa-circle fa-stack-2x"></i> | |
− | </a> | + | <i class="fa fa-book fa-stack-1x text-primary"></i> |
+ | </span> | ||
+ | <h4> | ||
+ | <strong>Notebook</strong> | ||
+ | </h4> | ||
+ | <p>Know more about agenda and what was done.</p> | ||
+ | <a href="https://2015.igem.org/Team:Cairo_Egypt/Notebook" class="btn btn-light">Learn More</a> | ||
</div> | </div> | ||
</div> | </div> | ||
− | <div class="col-md-6"> | + | <div class="col-md-3 col-sm-6"> |
− | <div class=" | + | <div class="service-item"> |
− | < | + | <span class="fa-stack fa-4x"> |
− | + | <i class="fa fa-circle fa-stack-2x"></i> | |
− | </a> | + | <i class="fa fa-smile-o fa-stack-1x text-primary"></i> |
+ | </span> | ||
+ | <h4> | ||
+ | <strong>Attributions</strong> | ||
+ | </h4> | ||
+ | <p>Know who did what in this project from the beginning</p> | ||
+ | <a href="https://2015.igem.org/Team:Cairo_Egypt/Attributions" class="btn btn-light">Learn More</a> | ||
</div> | </div> | ||
</div> | </div> | ||
+ | <div class="col-md-3 col-sm-6"> | ||
+ | <div class="service-item"> | ||
+ | <span class="fa-stack fa-4x"> | ||
+ | <i class="fa fa-circle fa-stack-2x"></i> | ||
+ | <i class="fa fa- fa-comments-o fa-stack-1x text-primary"></i> | ||
+ | </span> | ||
+ | <h4> | ||
+ | <strong>Collaborations</strong> | ||
+ | </h4> | ||
+ | <p>We contacted some teams, see them here</p> | ||
+ | <a href="https://2015.igem.org/Team:Cairo_Egypt/Collaborations" class="btn btn-light">Learn More</a> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="col-md-12 col-sm-12"> | ||
+ | <div id="carousel-example-generic" class="carousel slide" data-ride="carousel"> | ||
+ | <!-- Indicators --> | ||
+ | <ol class="carousel-indicators"> | ||
+ | <li data-target="#carousel-example-generic" data-slide-to="0" class="active"></li> | ||
+ | <li data-target="#carousel-example-generic" data-slide-to="1"></li> | ||
+ | <li data-target="#carousel-example-generic" data-slide-to="2"></li> | ||
+ | |||
+ | </ol> | ||
+ | |||
+ | <!-- Wrapper for slides --> | ||
+ | <div class="carousel-inner" role="listbox"> | ||
+ | <div class="item active"> | ||
+ | <img src="https://static.igem.org/mediawiki/2015/d/d7/Team-Cairo_Egypt_hme1.jpg" alt="..."> | ||
+ | </div> | ||
+ | |||
+ | <div class="item"> | ||
+ | <img src="https://static.igem.org/mediawiki/2015/4/41/Team-Cairo_Egypt_hme5.jpg" alt="..."> | ||
+ | </div> | ||
+ | <div class="item"> | ||
+ | <img src="https://static.igem.org/mediawiki/2015/e/e4/Team-Cairo_Egypt_hme6.jpg" alt="..."> | ||
+ | </div> | ||
+ | </div> | ||
+ | </div> | ||
+ | </div> | ||
</div> | </div> | ||
<!-- /.row (nested) --> | <!-- /.row (nested) --> | ||
− | |||
</div> | </div> | ||
<!-- /.col-lg-10 --> | <!-- /.col-lg-10 --> | ||
Line 189: | Line 227: | ||
<!-- /.container --> | <!-- /.container --> | ||
</section> | </section> | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
<!-- Map --> | <!-- Map --> | ||
Line 214: | Line 239: | ||
<div class="row"> | <div class="row"> | ||
<div class="col-lg-10 col-lg-offset-1 text-center"> | <div class="col-lg-10 col-lg-offset-1 text-center"> | ||
− | <h4><strong> | + | <h4><strong>IGEM | Egypt</strong> |
</h4> | </h4> | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
<br> | <br> | ||
<ul class="list-inline"> | <ul class="list-inline"> | ||
<li> | <li> | ||
− | <a href=" | + | <a href="https://www.facebook.com/iGEMEgypt"><i class="fa fa-facebook fa-fw fa-3x"></i></a> |
</li> | </li> | ||
<li> | <li> | ||
− | <a href=" | + | <a href="https://www.youtube.com/channel/UC5Wr8uJESsDN37EQ9QY1sAA"><i class="fa fa-youtube fa-fw fa-3x"></i></a> |
</li> | </li> | ||
<li> | <li> | ||
− | <a href=" | + | <a href="mailto:igem.egyptian.lab@gmail.com"><i class="fa fa-envelope fa-fw fa-3x"></i></a> |
+ | </li> | ||
+ | <li> | ||
+ | <a href="https://www.facebook.com/groups/714799951953916/"><i class="fa fa-globe fa-fw fa-3x"></i></a> | ||
+ | </li> | ||
+ | <li> | ||
+ | <a href="https://trello.com/b/n2gsYld5/admin"><i class="fa fa-trello fa-fw fa-3x"></i></a> | ||
</li> | </li> | ||
</ul> | </ul> | ||
<hr class="small"> | <hr class="small"> | ||
− | <p class="text-muted">Copyright © | + | <p class="text-muted">Copyright © IGEM | Egypt 2015</p> |
</div> | </div> | ||
</div> | </div> | ||
</div> | </div> | ||
</footer> | </footer> | ||
+ | |||
<!-- Bootstrap Core JavaScript --> | <!-- Bootstrap Core JavaScript --> | ||
Line 275: | Line 301: | ||
}); | }); | ||
</script> | </script> | ||
− | |||
− | |||
− | |||
</html> | </html> |
Latest revision as of 03:52, 19 September 2015
Breast cancer is the most common malignancy in women and constitutes 18% of all female cancers (Jemal et al., 2002) Although there has been a slight decrease in mortality in breast cancer patients (Schiffman et al., 2002), it is not uncommon for even early-stage breast cancer to metastasize. Therefore, novel therapeutic strategies are constantly being pursued (Bange et al., 2001). It has been reported that some bacterial species preferentially replicate and accumulate within tumors. At critical cell densities, the binding of a regulator protein to the signal leads to the switch on of genes controlled by QS and therefore a coordinated population response Moreover, they possess certain advantageous features such as motility, capacity to simultaneously carry and express multiple therapeutic proteins. Its elimination by antibiotics makes it a promising new strategy in cancer treatment. Azurin is a copper-containing redox protein with low molecular Weight which can efficiently induce cell apoptosis by raising the intracellular levels of p53 and Bax. It has been found that Azurin receptors are hyper expressed on the surfaces of cancer cells relative to their expression on the surfaces of normal cells. We do intend to modify genetic material of bacteria species that localize and induce expression of Azurin in presence of tumor only.Brief Description
What we have