Difference between revisions of "Team:Northeastern Boston"

 
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    <div id='bar_title' class='title'><a href="https://2015.igem.org/Team:Northeastern_Boston">
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      Northeastern</a>
 
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    <h1 id="home-header">NORTHEASTERN</h1>
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  <p>"Dr. George D. Yancopoulos, chief scientific officer of Regeneron, said the crisis had pointed up shortcomings in biodefense. 'Nobody is really prepared,' he said. 'Nobody in the world has rapid response capabilities.'"</p>
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  <p style="color: #585858; margin-top:10px">- New York Times, January 2015</p>
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  <h2 class='slide-content__title'>Standardizing Protein from Algae</h2>
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  <h3 class='triad__title'>Project</h3>
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  Humans need a quicker method for producing antibodies. Learn about our project.
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  <h3 class='triad__title'>Human Practices</h3>
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  Meetups, talks, collaboration, and some investigation of what synbio really means.
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  Three promoters, one fluorescent protein. We compared expression.
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The primary benefit of microalgae for antibodies is their quick and cheap scale-up. We envision kgs worth of antibody being produced by microalgae in raceway ponds for rapid and inexpensive availability.
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    <p>Northeastern is working to standardize protein production in microalgae. Chalmydomonas reinhardtii, the workhorse of algae research, is an attractive chassis for several reasons. Its primary carbon source is CO2, it rapidly divides, and it’s a capable of complex post-translational modifications.</p>
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<p>Microalgae are relatively inexpensive to scale, yet have all the production capabilities of other Eukaryotic organisms (di-sulfide bonds, and glycosylation). This capability could be exploited to treat human disease. For example, there was a shortage of an “antibody-cocktail” during the Ebola outbreak. Despite the existence of a promising therapy, existing production methods were too rigid to produce the volume needed to save lives. Northeastern’s iGEM team will investigate the potential of microalgae for therapeutic antibodies and other therapeutics proteins with an emphasis on neglected disease, particularly diseases with known-but-too-expensive treatments.</p>
 
 
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Latest revision as of 03:57, 19 September 2015

NORTHEASTERN

"Dr. George D. Yancopoulos, chief scientific officer of Regeneron, said the crisis had pointed up shortcomings in biodefense. 'Nobody is really prepared,' he said. 'Nobody in the world has rapid response capabilities.'"

- New York Times, January 2015

Standardizing Protein from Algae

Project

Humans need a quicker method for producing antibodies. Learn about our project.

Human Practices

Meetups, talks, collaboration, and some investigation of what synbio really means.

Interlab

Three promoters, one fluorescent protein. We compared expression.

The primary benefit of microalgae for antibodies is their quick and cheap scale-up. We envision kgs worth of antibody being produced by microalgae in raceway ponds for rapid and inexpensive availability.