Difference between revisions of "Team:San Andres"

 
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          <a href="https://2015.igem.org/Team:San_Andres" style="color:#000000">Home </a>  
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          <a href="https://2015.igem.org/Team:San_Andres/Team" style="color:#000000"> Team </a>  
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          <a href="https://2015.igem.org/Team:San_Andres/Description" style="color:#000000"> Project </a>
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          <a href="https://2015.igem.org/Team:San_Andres/Notebook" style="color:#000000"> Statistics</a>
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          <a href="https://2015.igem.org/Team:San_Andres/Experiments" style="color:#000000"> Enzymes</a>
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          <a href="https://2015.igem.org/Team:San_Andres/Notebook" style="color:#000000"> Metodology</a>
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          <a href="https://2015.igem.org/Team:San_Andres/Results" style=" color:#000000"> Results </a>
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          <a href="https://2015.igem.org/Team:San_Andres/Collaborations" style="color:#000000"> Future Projections </a>
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</style><!--navigation menu -->
 +
<br>
 +
<table style="width: 968px; height: 34px;"
 +
class="gwd-table-nb4m editable gwd-table-15ao">
 +
  <tbody>
 +
    <tr heigth="15px">
 +
    </tr>
 +
    <tr heigth="75px">
 +
      <td style="border: 3px solid rgb(29, 16, 3);"
 +
onmouseout="this.bgColor='#ffee1b'"
 +
onmouseover="this.bgColor='#6bb402'" align="center"
 +
bgcolor="#ffee1b" height="30">
 +
      <a href="https://2015.igem.org/Team:San_Andres"
 +
style="color: rgb(0, 0, 0);">Home </a> </td>
 +
      <td style="border: 3px solid black;"
 +
onmouseout="this.bgColor='#ffee1b'"
 +
onmouseover="this.bgColor='#6bb402'" align="center"
 +
bgcolor="#ffee1b" height="30">
 +
      <a href="https://2015.igem.org/Team:San_Andres/Team"
 +
style="color: rgb(0, 0, 0);"> Team</a>
 +
      </td>
 +
      <td style="border: 3px solid rgb(29, 16, 3);"
 +
onmouseout="this.bgColor='#ffee1b'"
 +
onmouseover="this.bgColor='#6bb402'" align="center"
 +
bgcolor="#ffee1b" height="30">
 +
      <a href="https://2015.igem.org/Team:San_Andres/Description"
 +
style="color: rgb(0, 0, 0);"> Project</a>
 +
      </td>
 +
      <td style="border: 3px solid rgb(29, 16, 3);"
 +
onmouseout="this.bgColor='#ffee1b'"
 +
onmouseover="this.bgColor='#6bb402'" align="center"
 +
bgcolor="#ffee1b" height="30">
 +
      <a href="https://2015.igem.org/Team:San_Andres/Parts"
 +
style="color: rgb(0, 0, 0);"> Parts</a>
 +
      </td>
 +
      <td style="border: 3px solid rgb(29, 16, 3);"
 +
onmouseout="this.bgColor='#ffee1b'"
 +
onmouseover="this.bgColor='#6bb402'" align="center"
 +
bgcolor="#ffee1b" height="30">
 +
      <a href="https://2015.igem.org/Team:San_Andres/Modeling"
 +
style="color: rgb(0, 0, 0);"> Modeling</a>
 +
      </td>
 +
      <td style="border: 3px solid rgb(29, 16, 3);"
 +
onmouseout="this.bgColor='#ffee1b'"
 +
onmouseover="this.bgColor='#6bb402'" align="center"
 +
bgcolor="#ffee1b" height="30"><a
 +
href="https://2015.igem.org/Team:San_Andres/Results"
 +
style="color: rgb(0, 0, 0);"> Results</a>
 +
      </td>
 +
    </tr>
 +
  </tbody>
 +
</table>
 +
<table style="width: 968px; height: 34px;"
 +
class="gwd-table-nb4m editable gwd-table-10nh">
 +
  <tbody>
 +
    <tr heigth="15px">
 +
    </tr>
 +
    <tr heigth="75px">
 +
      <td style="border: 3px solid rgb(29, 16, 3);"
 +
onmouseout="this.bgColor='#ffee1b'"
 +
onmouseover="this.bgColor='#6bb402'" align="center"
 +
bgcolor="#ffee1b" height="30">
 +
      <a href="https://2015.igem.org/Team:San_Andres/Notebook"
 +
style="color: rgb(0, 0, 0);">Notebook</a>
 +
      </td>
 +
      <td style="border: 3px solid rgb(29, 16, 3);"
 +
onmouseout="this.bgColor='#ffee1b'"
 +
onmouseover="this.bgColor='#6bb402'" align="center"
 +
bgcolor="#ffee1b" height="30">
 +
      <a href="https://2015.igem.org/Team:San_Andres/Practices"
 +
style="color: rgb(0, 0, 0);"> Human Practices</a>
 +
      </td>
 +
      <td style="border: 3px solid rgb(29, 16, 3);"
 +
onmouseout="this.bgColor='#ffee1b'"
 +
onmouseover="this.bgColor='#6bb402'" align="center"
 +
bgcolor="#ffee1b" height="30">
 +
      <a href="https://2015.igem.org/Team:San_Andres/Design"
 +
style="color: rgb(0, 0, 0);"> Future Projections</a>
 +
      </td>
 +
      <td style="border: 3px solid rgb(29, 16, 3);"
 +
onmouseout="this.bgColor='#ffee1b'"
 +
onmouseover="this.bgColor='#6bb402'" align="center"
 +
bgcolor="#ffee1b" height="30">
 +
      <a href="https://2015.igem.org/Team:San_Andres/Attributions"
 +
style="color: rgb(0, 0, 0);"> Attributions</a>
 +
      </td>
 +
      <td style="border: 3px solid rgb(29, 16, 3);"
 +
onmouseout="this.bgColor='#ffee1b'"
 +
onmouseover="this.bgColor='#6bb402'" align="center"
 +
bgcolor="#ffee1b" height="30">
 +
      <a href="https://2015.igem.org/Team:San_Andres/Collaborations"
 +
style="color: rgb(0, 0, 0);"> Collaborations</a>
 +
      </td>
 +
    </tr>
 +
  </tbody>
 +
</table>
 +
<div class="gwd-div-2ed9"></div>
 +
<div class="gwd-div-7xzo gwd-a-1thu">
 +
<h1 style="font-family: Algerian; font-weight: normal;"><big>Abstract</big></h1>
 +
<div style="text-align: justify;"><big
 +
style="font-family: Cambria;">The celiac
 +
disease affects 1 in 265 people worldwide and 15%
 +
of population in Chile. This in an irreversible autoimmune disease in
 +
which due to the presence of genes HLA DQ2 or HLA DQ8 in those
 +
affected, the consumption of foods containing gluten (all fods derived
 +
from wheat, barley, rye, etc.) cause an inflammation in small intestine
 +
causing multiple effects in the organism (diarrhea, constipation, porr
 +
absorption, among others) significantly affecting their quatily of life.</big><span
 +
style="font-family: Cambria;">
 +
</span><br style="font-family: Cambria;">
 +
<br style="font-family: Cambria;">
 +
<big style="font-family: Cambria;">Whereas the majority of
 +
the world food contains gluten, we
 +
propose a
 +
treatment for those who can't eat gluten, and can do so without
 +
problems. In detail, our project involves a system able to degrade
 +
gluten via the enzyme KumaMax and report the operation simultaneously
 +
with a red fluorescent protein. The foregoing, works in a genetically
 +
modified E. coli bacteria. With this project, in long run, we hope to
 +
improve the quality of life of all those reported with celiac disease.
 +
People who suffer from gluten intolerance have an adverse reaction to
 +
gluten proteins found in wheat, barley, and rye products.</big><span
 +
style="font-family: Cambria;">
 +
</span><br>
 +
</div>
 +
<big><br>
 +
</big>
 +
<div style="text-align: center;"><img
 +
style="width: 893px; height: 373px;" alt="File:Ex 2.jpg"
 +
src="https://static.igem.org/mediawiki/2015/thumb/9/93/Ex_2.jpg/800px-Ex_2.jpg"><br>
 +
<br>
 +
<h1
 +
style="font-family: Algerian; font-weight: normal; text-align: left;"><big><big>Medal</big></big></h1>
 +
<div style="text-align: center;"><big
 +
style="font-family: Cambria;"><big><big>We won a
 +
bronze medal for Chile!!!</big></big><br>
 +
<br>
 +
</big>
 +
<div style="text-align: center;"><img
 +
style="width: 414px; height: 481px;" alt="File:Bronze.png"
 +
src="https://static.igem.org/mediawiki/2015/thumb/f/f2/Bronze.png/515px-Bronze.png"
 +
srcset="/wiki/images/thumb/f/f2/Bronze.png/772px-Bronze.png 1.5x, /wiki/images/thumb/f/f2/Bronze.png/1029px-Bronze.png 2x">&nbsp;<img
 +
style="width: 513px; height: 330px;"
 +
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Latest revision as of 23:31, 4 October 2015

<endnote><head> <title><endnote><head> <meta> <title> wiki wiki exp wiki wiki wiki 2   File:Gluten-s-Job.jpeg

Home Team Project Parts Modeling Results
Notebook Human Practices Future Projections Attributions Collaborations

Abstract

The celiac disease affects 1 in 265 people worldwide and 15% of population in Chile. This in an irreversible autoimmune disease in which due to the presence of genes HLA DQ2 or HLA DQ8 in those affected, the consumption of foods containing gluten (all fods derived from wheat, barley, rye, etc.) cause an inflammation in small intestine causing multiple effects in the organism (diarrhea, constipation, porr absorption, among others) significantly affecting their quatily of life.

Whereas the majority of the world food contains gluten, we propose a treatment for those who can't eat gluten, and can do so without problems. In detail, our project involves a system able to degrade gluten via the enzyme KumaMax and report the operation simultaneously with a red fluorescent protein. The foregoing, works in a genetically modified E. coli bacteria. With this project, in long run, we hope to improve the quality of life of all those reported with celiac disease. People who suffer from gluten intolerance have an adverse reaction to gluten proteins found in wheat, barley, and rye products.

File:Ex 2.jpg

Medal

We won a bronze medal for Chile!!!
File:Bronze.png File:Chile-153367 640.png