Difference between revisions of "Team:HSNU-TAIPEI/Project/Benzo a pyrene"
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<h2><font color="#008b8b"> ✡ Circuit Design</font></h2> | <h2><font color="#008b8b"> ✡ Circuit Design</font></h2> | ||
| − | <img src="https://static.igem.org/mediawiki/2015/ | + | <img src="https://static.igem.org/mediawiki/2015/e/ed/2015hsnu-benzo-a-pyrene_2.png" height="250" width="400"> |
<p><font face="Comic Sans MS"> MerR可以和汞結合然後改變DNA的結構好讓RNA聚合酶方便轉入。</font></p> | <p><font face="Comic Sans MS"> MerR可以和汞結合然後改變DNA的結構好讓RNA聚合酶方便轉入。</font></p> | ||
<p><font face="Comic Sans MS"> PmerT可以被MerR控制。PmerT步行進行轉錄是因為MerR會改變PmerT的</font></p> | <p><font face="Comic Sans MS"> PmerT可以被MerR控制。PmerT步行進行轉錄是因為MerR會改變PmerT的</font></p> | ||
Revision as of 13:27, 29 August 2015
Benzo[a]pyrene
✡ Introduction
(1)Why do we detect benzo[a]pyrene?
Because when food,such as fried food ,which is heated above 300 degrees
celcius,food will release benzo[a]pyrene recycled oil usually contain
benzo[a]pyrene[1].
(2)Harm?
Pathway:from skin,breathing in,eating Carcinogenic,environmental
pollution, Skin irritation,eye irritation[1].
(3)Taiwanese regulation
[2]
(4)National regulation
Europe:The same to Taiwanese regulation[2]
American:The MCL has been set at 0.2 ppb[3]
✡ Circuit Design
MerR可以和汞結合然後改變DNA的結構好讓RNA聚合酶方便轉入。
PmerT可以被MerR控制。PmerT步行進行轉錄是因為MerR會改變PmerT的
形狀。總而言之，只要汞與MerR結合，後續反應就可進行。(註3)(註4)
✡ Result
✡ Reference
(註1)Metabolism of mercury, administered as methylmercuric chloride or mercuric chloride, by lactating ruminants.
(註2)台北醫學大學公共衛生學系碩士班碩士論文Graduate Institute.
(註3)Brown, N. L., J. V. Stoyanov, et al. (2003). "The MerR family of transcriptional regulators." FEMS Microbiol Rev 27(2-3): 145-163.
(註4)Park, S. J., J. Wireman, et al. (1992). "Genetic analysis of the Tn21 mer operator-promoter." J Bacteriol 174(7): 2160-2171.