Difference between revisions of "Team:Harvard BioDesign/Project"
| Line 88: | Line 88: | ||
<h4> Content </h4> | <h4> Content </h4> | ||
<ul> | <ul> | ||
| − | <li><a href="# | + | <li><a href="#introduction" id="top-link" class="skel-layers-ignoreHref"><span class="icon fa-home">Introduction</span></a></li> |
| − | <li><a href="# | + | <li><a href="#foundations" id="overview-link" class="skel-layers-ignoreHref"><span class="icon fa-th">Foundations</span></a></li> |
| − | <li><a href="# | + | <li><a href="#applications" id="sitemap-link" class="skel-layers-ignoreHref"><span class="icon fa-user">Applications</span></a></li> |
</ul> | </ul> | ||
</nav> | </nav> | ||
| Line 132: | Line 132: | ||
<div id="main"> | <div id="main"> | ||
| − | |||
| − | <section id=" | + | <section id="Introduction" class="one dark cover"> |
<img src="https://static.igem.org/mediawiki/2015/8/85/Harvard_2015_Project.png" alt="Project Logo" style="width:200px;height:200px;"/> | <img src="https://static.igem.org/mediawiki/2015/8/85/Harvard_2015_Project.png" alt="Project Logo" style="width:200px;height:200px;"/> | ||
<header><h2>BactoGrip</h2></header> | <header><h2>BactoGrip</h2></header> | ||
| − | |||
| − | |||
| − | |||
| − | |||
<div class="container"> | <div class="container"> | ||
| − | + | <h2>About our project</h2> | |
| − | <h2>About our project</h2 | + | |
| − | + | ||
<p>Our team is engineering <i>E. coli</i> to bind to colon cancer cells through the use of their type I pili, which are hair-like appendages | <p>Our team is engineering <i>E. coli</i> to bind to colon cancer cells through the use of their type I pili, which are hair-like appendages | ||
| Line 163: | Line 156: | ||
<!-- Experiments --> | <!-- Experiments --> | ||
| − | <section id="experiments" class=" | + | <section id="experiments" class="two"> |
<div class="container"> | <div class="container"> | ||
| Line 176: | Line 169: | ||
<!-- Design --> | <!-- Design --> | ||
| − | <section id="design" class=" | + | <section id="design" class="three"> |
<div class="container"> | <div class="container"> | ||
Revision as of 12:34, 8 September 2015
BactoGrip
About our project
Our team is engineering E. coli to bind to colon cancer cells through the use of their type I pili, which are hair-like appendages
that have an adhesive domain. Naturally, the strains in E. coli that produce pili bind to alpha-D-mannose, which can cause urinary tract infections.
However, our team is altering a non-harmful strain to produce pili using a modified Fim gene in order to localize the bacteria as a tool. For treatment of cancer,
once the bacteria are localized on the cells, the next step is to make them