Difference between revisions of "Team:San Andres"

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          <a href="https://2015.igem.org/Team:San_Andres" style="color: rgb(0, 0, 0);">Home </a>  
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          <a href="https://2015.igem.org/Team:San_Andres/Team" style="color: rgb(0, 0, 0);"> Team </a>  
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          <a href="https://2015.igem.org/Team:San_Andres/Description" style="color: rgb(0, 0, 0);"> Project </a>
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          <a href="https://2015.igem.org/Team:San_Andres/Notebook" style="color: rgb(0, 0, 0);"> Statistics</a>
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          <a href="https://2015.igem.org/Team:San_Andres/Parts" style="color: rgb(0, 0, 0);"> Parts</a>
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          <a href="https://2015.igem.org/Team:San_Andres/Modeling" style="color: rgb(0, 0, 0);"> Metodology</a>
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          <a href="https://2015.igem.org/Team:San_Andres/Results" style="color: rgb(0, 0, 0);"> Results </a>
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          <a href="https://igem.org/Team_List?year=2015">
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      <a href="https://2015.igem.org/Team:San_Andres"
            <img src="https://static.igem.org/mediawiki/igem.org/6/60/Igemlogo_300px.png" width="55">
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      <a href="https://2015.igem.org/Team:San_Andres/Team"
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      <a href="https://2015.igem.org/Team:San_Andres/Description"
 +
style="color: rgb(0, 0, 0);"> Project </a>
 +
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 +
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 +
      <a href="https://2015.igem.org/Team:San_Andres/Notebook"
 +
style="color: rgb(0, 0, 0);"> Statistics</a>
 +
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 +
      <td style="border: 2px solid black;"
 +
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 +
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 +
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      <a href="https://2015.igem.org/Team:San_Andres/Experiments"
 +
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 +
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 +
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 +
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 +
      <a href="https://2015.igem.org/Team:San_Andres/Parts"
 +
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 +
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 +
      <td style="border: 2px solid black;"
 +
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 +
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      <a href="https://2015.igem.org/Team:San_Andres/Modeling"
 +
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      <a href="https://2015.igem.org/Team:San_Andres/Results"
 +
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bgcolor="#ffa600" height="45">
 +
      <a href="https://2015.igem.org/Team:San_Andres/Collaborations"
 +
style="color: rgb(0, 0, 0);"> Future Projections </a>
 +
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      <a href="https://igem.org/Team_List?year=2015"><img
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<h1>Home</h1>
+
<h1><big>Home</big>
<div style="text-align: left;"><big>Our project of
+
</h1>
entrepreneurship and innovation which is called Gluten's
+
<p class="MsoNormal"><big><big><span
Job belongs to the international competition IGEM (international
+
style="font-family: &quot;Tahoma&quot;,&quot;sans-serif&quot;;" lang="EN-US">The
genetically engineered machine) competition of synthetic biology, where
+
celiac disease affects 1 in 265 people worldwide
students from around the world give their
+
and 15% of population in Chile. This is an irreversible autoimmune
project in Boston, Massachusetts, USA. Our objective is to generate an
+
disease in
effective alternative for the treatment of celiac disease through the
+
which due to the presence of genes HLA DQ2 or HLA-DQ8 in those
modification of the genetic material with Biobricks.&nbsp;<span
+
affected, the
id="result_box" class="short_text" lang="en"><span
+
consumption of foods containing gluten (all foods derived from wheat,
  class="hps">We belong to the San Andres School.</span><span></span></span></big></div>
+
barley,
 +
rye, etc.) cause an inflammation in the small intestine causing
 +
multiple
 +
effects in the organism (diarrhea, constipation, poor absorption, among
 +
others)
 +
significantly affecting their quality of life. <o:p></o:p></span></big></big></p>
 +
<p class="MsoNormal"><span
 +
  style="font-family: &quot;Tahoma&quot;,&quot;sans-serif&quot;;" lang="EN-US"><big><big>Whereas
 +
the majority of the world food contains
 +
gluten, we propose a treatment for those who can’t eat gluten, and can
 +
do so
 +
without problems. In detail, our project involves a system able to
 +
degrade
 +
gluten via the enzyme KumaMax and report the operation simultaneously
 +
with a
 +
red fluorescent protein. The foregoing, works in a genetically modified
 +
E. coli
 +
bacteria. With this project, in the long run, we hope to improve the
 +
quality of
 +
life of all those reported with celiac disease.</big></big><o:p></o:p></span></p>
 +
<p class="MsoNormal"><span
 +
style="font-size: 12pt; line-height: 115%; font-family: &quot;Tahoma&quot;,&quot;sans-serif&quot;;"
 +
lang="EN-US"><big></big><o:p></o:p></span></p>
 
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Revision as of 02:12, 15 July 2015

wiki wiki 2

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The celiac disease affects 1 in 265 people worldwide and 15% of population in Chile. This is an irreversible autoimmune disease in which due to the presence of genes HLA DQ2 or HLA-DQ8 in those affected, the consumption of foods containing gluten (all foods derived from wheat, barley, rye, etc.) cause an inflammation in the small intestine causing multiple effects in the organism (diarrhea, constipation, poor absorption, among others) significantly affecting their quality of life.

Whereas the majority of the world food contains gluten, we propose a treatment for those who can’t eat gluten, and can do so without problems. In detail, our project involves a system able to degrade gluten via the enzyme KumaMax and report the operation simultaneously with a red fluorescent protein. The foregoing, works in a genetically modified E. coli bacteria. With this project, in the long run, we hope to improve the quality of life of all those reported with celiac disease.


    
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