Difference between revisions of "Team:Harvard BioDesign"

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                 <h2 class="alt">Welcome to the <strong>Harvard BioDesign 2015</strong> wiki!</br>
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              This site template designed by <a href="http://html5up.net">HTML5 UP</a>.</h2>
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                 <p>The "official" place where flocculation happens and llamas are appreciated.</p>
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Revision as of 16:10, 15 July 2015


Prologue by HTML5 UP

Welcome to the Harvard BioDesign 2015 wiki!


The "official" place where flocculation happens and llamas are appreciated.

About Our Project

Our team is engineering E. coli to bind to colon cancer cells through the use of their type I pili, which are hair-like appendages that have an adhesive domain. Naturally, the strains in E. coli that produce pili bind to alpha-D-mannose, which can cause urinary track infections. However, our team is altering a non-harmful strain to produce pili using a modified Fim gene in order to localize the bacteria as a tool. For treatment of cancer, once the bacteria are localized on the cells, the next step is to make the capable of producing a concentrated toxin or to administer a therapeutic. Other potential applications for our E. coli include water pollution clean up through methods such as flocculation and targeting areas through GFP.

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About Me

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Contact

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